Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-Phd |
| Location | 3964104..3964801 | Replicon | chromosome |
| Accession | NZ_AP024469 | ||
| Organism | Geobacter sp. SVR | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | GSVR_RS18580 | Protein ID | WP_173195302.1 |
| Coordinates | 3964104..3964523 (-) | Length | 140 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | GSVR_RS18585 | Protein ID | WP_173195303.1 |
| Coordinates | 3964520..3964801 (-) | Length | 94 a.a. |
Genomic Context
Location: 3960630..3962534 (1905 bp)
Type: Others
Protein ID: WP_173195300.1
Type: Others
Protein ID: WP_173195300.1
Location: 3959983..3960342 (360 bp)
Type: Others
Protein ID: WP_173195299.1
Type: Others
Protein ID: WP_173195299.1
Location: 3962655..3963572 (918 bp)
Type: Others
Protein ID: WP_173195890.1
Type: Others
Protein ID: WP_173195890.1
Location: 3963727..3964062 (336 bp)
Type: Others
Protein ID: WP_173195301.1
Type: Others
Protein ID: WP_173195301.1
Location: 3964104..3964523 (420 bp)
Type: Toxin
Protein ID: WP_173195302.1
Type: Toxin
Protein ID: WP_173195302.1
Location: 3964520..3964801 (282 bp)
Type: Antitoxin
Protein ID: WP_173195303.1
Type: Antitoxin
Protein ID: WP_173195303.1
Location: 3964899..3965207 (309 bp)
Type: Others
Protein ID: WP_173195304.1
Type: Others
Protein ID: WP_173195304.1
Location: 3965188..3965460 (273 bp)
Type: Others
Protein ID: WP_173195892.1
Type: Others
Protein ID: WP_173195892.1
Location: 3965553..3966785 (1233 bp)
Type: Others
Protein ID: WP_173195305.1
Type: Others
Protein ID: WP_173195305.1
Location: 3966832..3968409 (1578 bp)
Type: Others
Protein ID: WP_173195306.1
Type: Others
Protein ID: WP_173195306.1
Location: 3968499..3969269 (771 bp)
Type: Others
Protein ID: WP_173195894.1
Type: Others
Protein ID: WP_173195894.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GSVR_RS18560 | 3959983..3960342 | - | 360 | WP_173195299.1 | hypothetical protein | - |
| GSVR_RS18565 | 3960630..3962534 | + | 1905 | WP_173195300.1 | transglycosylase domain-containing protein | - |
| GSVR_RS18570 | 3962655..3963572 | - | 918 | WP_173195890.1 | tRNA-dihydrouridine synthase family protein | - |
| GSVR_RS18575 | 3963727..3964062 | - | 336 | WP_173195301.1 | toxin | - |
| GSVR_RS18580 | 3964104..3964523 | - | 420 | WP_173195302.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| GSVR_RS18585 | 3964520..3964801 | - | 282 | WP_173195303.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| GSVR_RS18590 | 3964899..3965207 | - | 309 | WP_173195304.1 | BrnA antitoxin family protein | - |
| GSVR_RS18595 | 3965188..3965460 | - | 273 | WP_173195892.1 | BrnT family toxin | - |
| GSVR_RS18600 | 3965553..3966785 | - | 1233 | WP_173195305.1 | LL-diaminopimelate aminotransferase | - |
| GSVR_RS18605 | 3966832..3968409 | - | 1578 | WP_173195306.1 | GGDEF domain-containing protein | - |
| GSVR_RS18610 | 3968499..3969269 | - | 771 | WP_173195894.1 | MetQ/NlpA family ABC transporter substrate-binding protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | htpB / adeG | 3676406..3996929 | 320523 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 140 a.a. Molecular weight: 15554.91 Da Isoelectric Point: 4.8065
>T38466 WP_173195302.1 NZ_AP024469:c3964523-3964104 [Geobacter sp. SVR]
VKYLLDTCLISELVKKEPNPSVVRWLDEQDEQKLFLSVLNVGELQKGISKLPNGAKKDELQAWVTLDLVERFTGRILDLD
LATALCWGRQQGEAERNGEKLPVMDALIAATAAAHGLVVVTRNVSDMERCGARVWNPWE
VKYLLDTCLISELVKKEPNPSVVRWLDEQDEQKLFLSVLNVGELQKGISKLPNGAKKDELQAWVTLDLVERFTGRILDLD
LATALCWGRQQGEAERNGEKLPVMDALIAATAAAHGLVVVTRNVSDMERCGARVWNPWE
Download Length: 420 bp
>T38466 NZ_AP024469:c3964523-3964104 [Geobacter sp. SVR]
GTGAAATATCTGCTCGATACCTGTCTGATTTCAGAACTGGTAAAAAAAGAGCCAAACCCGTCGGTAGTCAGGTGGCTGGA
CGAGCAGGACGAACAAAAGCTCTTTCTGAGTGTGCTGAACGTGGGGGAGTTGCAGAAGGGTATCAGCAAACTTCCGAACG
GTGCCAAGAAGGATGAGCTGCAGGCATGGGTCACGCTCGACTTGGTGGAGCGTTTTACCGGGCGGATCCTGGACCTCGAC
CTGGCGACAGCGCTATGCTGGGGACGACAGCAGGGGGAAGCGGAACGAAACGGCGAAAAGCTGCCGGTCATGGACGCACT
GATTGCTGCCACGGCTGCAGCCCATGGCCTGGTGGTGGTGACGCGCAATGTCAGTGATATGGAACGTTGCGGTGCACGCG
TGTGGAATCCGTGGGAGTAA
GTGAAATATCTGCTCGATACCTGTCTGATTTCAGAACTGGTAAAAAAAGAGCCAAACCCGTCGGTAGTCAGGTGGCTGGA
CGAGCAGGACGAACAAAAGCTCTTTCTGAGTGTGCTGAACGTGGGGGAGTTGCAGAAGGGTATCAGCAAACTTCCGAACG
GTGCCAAGAAGGATGAGCTGCAGGCATGGGTCACGCTCGACTTGGTGGAGCGTTTTACCGGGCGGATCCTGGACCTCGAC
CTGGCGACAGCGCTATGCTGGGGACGACAGCAGGGGGAAGCGGAACGAAACGGCGAAAAGCTGCCGGTCATGGACGCACT
GATTGCTGCCACGGCTGCAGCCCATGGCCTGGTGGTGGTGACGCGCAATGTCAGTGATATGGAACGTTGCGGTGCACGCG
TGTGGAATCCGTGGGAGTAA
Antitoxin
Download Length: 94 a.a. Molecular weight: 10739.99 Da Isoelectric Point: 7.4041
>AT38466 WP_173195303.1 NZ_AP024469:c3964801-3964520 [Geobacter sp. SVR]
MKTNKKDRSSHDREWQLQEAKNRLSQVVDQALHDGPQTITLRGKPAAVLLSFDEYRNLTRPHTGLSQFFRQSPLHDVELD
VSRSADLSREVEL
MKTNKKDRSSHDREWQLQEAKNRLSQVVDQALHDGPQTITLRGKPAAVLLSFDEYRNLTRPHTGLSQFFRQSPLHDVELD
VSRSADLSREVEL
Download Length: 282 bp
>AT38466 NZ_AP024469:c3964801-3964520 [Geobacter sp. SVR]
ATGAAAACAAATAAAAAGGACCGTTCGTCGCATGACCGGGAATGGCAGCTCCAGGAAGCTAAAAATCGTCTGAGCCAGGT
GGTCGATCAGGCGCTACATGATGGTCCGCAGACAATTACCTTGCGGGGCAAACCGGCAGCCGTTCTGCTTTCTTTTGATG
AGTACCGCAACCTGACCAGGCCGCACACGGGCCTGTCGCAATTCTTCCGCCAATCCCCTTTGCACGATGTAGAGCTGGAT
GTCAGCCGCAGCGCCGACCTCTCCAGGGAGGTTGAGCTGTGA
ATGAAAACAAATAAAAAGGACCGTTCGTCGCATGACCGGGAATGGCAGCTCCAGGAAGCTAAAAATCGTCTGAGCCAGGT
GGTCGATCAGGCGCTACATGATGGTCCGCAGACAATTACCTTGCGGGGCAAACCGGCAGCCGTTCTGCTTTCTTTTGATG
AGTACCGCAACCTGACCAGGCCGCACACGGGCCTGTCGCAATTCTTCCGCCAATCCCCTTTGCACGATGTAGAGCTGGAT
GTCAGCCGCAGCGCCGACCTCTCCAGGGAGGTTGAGCTGTGA