Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1666908..1667536 Replicon chromosome
Accession NZ_AP024469
Organism Geobacter sp. SVR

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GSVR_RS07710 Protein ID WP_173197397.1
Coordinates 1666908..1667309 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GSVR_RS07715 Protein ID WP_173197399.1
Coordinates 1667309..1667536 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GSVR_RS07690 1662099..1662995 - 897 WP_173197389.1 rod shape-determining protein -
GSVR_RS07695 1663257..1664042 - 786 WP_173197391.1 TIGR03915 family putative DNA repair protein -
GSVR_RS07700 1664042..1665337 - 1296 WP_173197393.1 putative DNA modification/repair radical SAM protein -
GSVR_RS07705 1665557..1666924 + 1368 WP_173197395.1 DUF2029 domain-containing protein -
GSVR_RS07710 1666908..1667309 - 402 WP_173197397.1 type II toxin-antitoxin system VapC family toxin Toxin
GSVR_RS07715 1667309..1667536 - 228 WP_173197399.1 antitoxin Antitoxin
GSVR_RS07720 1667650..1669137 - 1488 WP_173197401.1 glycosyltransferase -
GSVR_RS07725 1669174..1669677 - 504 WP_173197403.1 hypothetical protein -
GSVR_RS07730 1669780..1670658 - 879 WP_173197405.1 sulfurtransferase -
GSVR_RS07735 1670689..1671639 - 951 WP_173197407.1 arsenosugar biosynthesis radical SAM protein ArsS -
GSVR_RS07740 1671654..1671986 - 333 WP_173197409.1 arsenosugar biosynthesis-associated peroxidase-like protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14537.91 Da        Isoelectric Point: 4.8893

>T38465 WP_173197397.1 NZ_AP024469:c1667309-1666908 [Geobacter sp. SVR]
MKLLLDTNICIYIIKQQPAAVLERFLGYQVGEIALSSITVAELRYGVAKSAHREKNAQALDEFIIPLEVVSFDEEAARVY
GEIRAALEKAGTPVGAMDMLIAAHALSLGIPLVTNNTREFGRIPALTLLNWAD

Download         Length: 402 bp

>T38465 NZ_AP024469:c1667309-1666908 [Geobacter sp. SVR]
ATGAAGCTGCTGCTCGACACCAATATCTGCATCTACATTATCAAGCAGCAGCCGGCTGCCGTGCTCGAACGGTTTCTGGG
GTATCAGGTCGGAGAGATCGCACTGTCCTCCATTACGGTTGCGGAGTTGCGCTACGGTGTCGCCAAAAGTGCCCACCGTG
AGAAGAACGCTCAGGCCCTGGACGAGTTCATCATTCCGCTGGAAGTCGTGTCGTTCGATGAGGAAGCAGCCCGCGTCTAT
GGCGAGATCCGGGCTGCGCTGGAAAAAGCGGGCACGCCGGTCGGCGCCATGGATATGCTGATTGCTGCCCACGCGCTGTC
CCTGGGTATTCCCCTGGTTACCAACAACACCCGCGAATTTGGGCGCATCCCTGCCCTTACCCTTCTCAACTGGGCGGACT
GA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8776.95 Da        Isoelectric Point: 10.0134

>AT38465 WP_173197399.1 NZ_AP024469:c1667536-1667309 [Geobacter sp. SVR]
MKTAKIFQNGQSQAVRLPREFRFDDSEVFIKKSGNVVQLIPRSGSWNSLFDSLKKFSGDFMAERIQPEFDKRDEF

Download         Length: 228 bp

>AT38465 NZ_AP024469:c1667536-1667309 [Geobacter sp. SVR]
ATGAAGACGGCGAAAATATTTCAGAACGGCCAGAGTCAGGCTGTCAGGCTTCCCAGGGAGTTCCGCTTCGACGACAGCGA
AGTGTTCATCAAAAAAAGCGGCAATGTGGTGCAGTTGATCCCCCGTAGCGGCTCCTGGAACTCCCTGTTCGACAGTCTGA
AAAAATTTTCCGGCGACTTCATGGCCGAACGCATACAACCGGAGTTCGACAAACGGGACGAGTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References