38463

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 6058315..6058834 Replicon chromosome
Accession NZ_AP024464
Organism Pseudomonas amygdali pv. tabaci strain 6605

Toxin (Protein)


Gene name relE Uniprot ID Q48Q48
Locus tag Pta6605_RS26920 Protein ID WP_002551445.1
Coordinates 6058315..6058605 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0P9WSS8
Locus tag Pta6605_RS26925 Protein ID WP_016982665.1
Coordinates 6058595..6058834 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Pta6605_RS26905 (Pta6605_54110) 6055041..6055835 + 795 WP_016981236.1 hypothetical protein -
Pta6605_RS26910 (Pta6605_54140) 6056451..6057065 - 615 WP_016981235.1 histidine phosphatase family protein -
Pta6605_RS26915 (Pta6605_54150) 6057345..6058082 + 738 WP_005746662.1 hypothetical protein -
Pta6605_RS26920 (Pta6605_54160) 6058315..6058605 - 291 WP_002551445.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Pta6605_RS26925 (Pta6605_54170) 6058595..6058834 - 240 WP_016982665.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
Pta6605_RS26930 (Pta6605_54180) 6058998..6059471 - 474 WP_016982664.1 GNAT family N-acetyltransferase -
Pta6605_RS26935 (Pta6605_54190) 6059573..6060121 - 549 WP_016982663.1 GNAT family N-acetyltransferase -
Pta6605_RS26940 (Pta6605_54200) 6060281..6060775 + 495 WP_004667254.1 hypothetical protein -
Pta6605_RS26945 (Pta6605_54210) 6060809..6062083 - 1275 WP_016982662.1 OprD family porin -
Pta6605_RS26950 (Pta6605_54220) 6062298..6062531 - 234 WP_002551440.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-70)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11316.19 Da        Isoelectric Point: 10.2579

>T38463 WP_002551445.1 NZ_AP024464:c6058605-6058315 [Pseudomonas amygdali pv. tabaci]
MTYNLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
REREEVYRKATDRLGR

Download         Length: 291 bp

>T38463 NZ_AP024464:c6058605-6058315 [Pseudomonas amygdali pv. tabaci]
ATGACCTATAACCTCGAATTCGATGCGCGGGCTCTAAAGGAATGGCACAAATTAGGAGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCTCCGCGTGTTGAAGCCAATCGTCTGCATGCATTGCCTGACTGCTACAAAATCA
AACTGCGCAGTAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCGGTAGACAAG
CGTGAACGGGAAGAGGTTTATCGCAAGGCGACGGACCGGCTGGGTAGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8985.37 Da        Isoelectric Point: 4.6017

>AT38463 WP_016982665.1 NZ_AP024464:c6058834-6058595 [Pseudomonas amygdali pv. tabaci]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLATPQRVKVSLDDL

Download         Length: 240 bp

>AT38463 NZ_AP024464:c6058834-6058595 [Pseudomonas amygdali pv. tabaci]
ATGGCGTCTATCAACGTTCGTATCGACGACGATCTCAAAGCGCGTGCTTACCTCGAGCTGGAAAAGCTTGGCGTCACCCC
CTCGGAGTTGCTGCGCCAAACCCTGCAGTACGTAGCTGAGCGTGGTCAGCTACCCTTCAAGACGGTTCTGATGACAGAGG
AAGACGAAGCGCTGTTGGCAACTGTGCGTGAGCGCCTTGCAACTCCGCAGCGGGTCAAGGTTTCACTGGATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G4DBS4

Antitoxin

Source ID Structure
AlphaFold DB A0A0P9WSS8

References