Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 951616..952211 Replicon chromosome
Accession NZ_AP024464
Organism Pseudomonas amygdali pv. tabaci strain 6605

Toxin (Protein)


Gene name relE Uniprot ID A0A0Q0BQQ0
Locus tag Pta6605_RS04285 Protein ID WP_005782087.1
Coordinates 951909..952211 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0P9S822
Locus tag Pta6605_RS04280 Protein ID WP_005746689.1
Coordinates 951616..951906 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Pta6605_RS04265 (Pta6605_08550) 949178..950551 - 1374 WP_005746685.1 PepSY domain-containing protein -
Pta6605_RS04270 (Pta6605_08560) 950636..950995 - 360 WP_054076854.1 DUF2946 domain-containing protein -
Pta6605_RS04275 (Pta6605_08570) 951084..951545 - 462 WP_002555389.1 copper chaperone PCu(A)C -
Pta6605_RS04280 (Pta6605_08580) 951616..951906 - 291 WP_005746689.1 putative addiction module antidote protein Antitoxin
Pta6605_RS04285 951909..952211 - 303 WP_005782087.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Pta6605_RS04290 (Pta6605_08590) 952361..953101 - 741 WP_016982356.1 cobalt-precorrin-6A reductase -
Pta6605_RS04295 (Pta6605_08600) 953098..954210 - 1113 WP_004655757.1 cobalt-precorrin-5B (C(1))-methyltransferase -
Pta6605_RS04300 (Pta6605_08610) 954210..955412 - 1203 WP_016982357.1 bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cobalt-precorrin-6B (C(15))-methyltransferase -
Pta6605_RS04305 (Pta6605_08620) 955538..956878 + 1341 WP_016982358.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-86)

Antitoxin

Uncharacterized protein HI1420

(4-95)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11507.24 Da        Isoelectric Point: 10.6008

>T38459 WP_005782087.1 NZ_AP024464:c952211-951909 [Pseudomonas amygdali pv. tabaci]
MNRFEQTPAFAEWLRSLKDSIGRARILARIRAAELGNFGDCDALGQGVRELRIHHGPGYRVYFTRRTGVVYLLLIAGDKS
SQKRDIKFARQLARELCERE

Download         Length: 303 bp

>T38459 NZ_AP024464:c952211-951909 [Pseudomonas amygdali pv. tabaci]
ATGAATCGCTTTGAACAGACGCCCGCTTTTGCGGAGTGGTTAAGGTCGTTGAAGGACTCCATTGGCAGAGCTCGAATTCT
GGCTCGAATAAGAGCAGCAGAGCTCGGTAACTTCGGGGACTGCGATGCTTTAGGTCAAGGCGTCAGAGAGCTACGAATAC
ACCATGGACCAGGTTATCGGGTGTATTTTACCCGACGCACGGGTGTGGTTTACCTGCTCTTGATCGCTGGTGACAAATCG
TCTCAAAAGCGCGACATAAAATTTGCCAGACAGCTGGCGAGAGAGCTCTGTGAGAGGGAGTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10500.87 Da        Isoelectric Point: 4.5720

>AT38459 WP_005746689.1 NZ_AP024464:c951906-951616 [Pseudomonas amygdali pv. tabaci]
MNNETTPFDTVDYLKTPEDMANYLDACLEEDSGDGLLVRAALNDIARAYGMTQIARDTGLGRESLYKALGANGNPEFTTI
MKVVRAMGIKLHASTR

Download         Length: 291 bp

>AT38459 NZ_AP024464:c951906-951616 [Pseudomonas amygdali pv. tabaci]
ATGAACAACGAGACGACACCGTTCGATACCGTCGACTATTTGAAGACACCTGAAGATATGGCCAATTATCTGGATGCGTG
TCTTGAAGAGGATTCAGGAGACGGGCTGCTCGTAAGGGCCGCGCTGAACGACATAGCAAGGGCTTATGGCATGACACAAA
TCGCACGTGATACAGGTCTTGGTCGTGAGAGCCTCTACAAAGCGCTGGGTGCAAACGGTAATCCAGAGTTCACGACCATC
ATGAAAGTCGTGAGGGCGATGGGGATCAAACTACACGCAAGTACGCGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0Q0BQQ0

Antitoxin

Source ID Structure
AlphaFold DB A0A0P9S822

References