Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 2957060..2957688 Replicon chromosome
Accession NZ_AP024463
Organism Arachnia rubra strain SK-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SK1NUM_RS13420 Protein ID WP_223927621.1
Coordinates 2957290..2957688 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SK1NUM_RS13415 Protein ID WP_212323090.1
Coordinates 2957060..2957293 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SK1NUM_RS13390 (SK1NUM_26810) 2952729..2953667 - 939 WP_223927620.1 ABC transporter ATP-binding protein -
SK1NUM_RS13395 (SK1NUM_26820) 2953902..2954900 - 999 WP_212323078.1 serine hydrolase domain-containing protein -
SK1NUM_RS13400 2955042..2955482 - 441 WP_212323081.1 hypothetical protein -
SK1NUM_RS13405 (SK1NUM_26850) 2955564..2956580 - 1017 WP_212323084.1 hypothetical protein -
SK1NUM_RS13410 (SK1NUM_26860) 2956577..2956927 - 351 WP_212323087.1 GntR family transcriptional regulator -
SK1NUM_RS13415 (SK1NUM_26870) 2957060..2957293 + 234 WP_212323090.1 hypothetical protein Antitoxin
SK1NUM_RS13420 (SK1NUM_26880) 2957290..2957688 + 399 WP_223927621.1 PIN domain-containing protein Toxin
SK1NUM_RS13425 (SK1NUM_26890) 2957751..2958521 + 771 WP_212323093.1 peroxide stress protein YaaA -
SK1NUM_RS13430 (SK1NUM_26900) 2958910..2959455 + 546 WP_212323096.1 NAD(P)H-dependent oxidoreductase -
SK1NUM_RS13440 (SK1NUM_26910) 2961076..2961252 - 177 WP_212323102.1 plantaricin C family lantibiotic -
SK1NUM_RS13445 (SK1NUM_26920) 2961646..2962554 + 909 WP_212323105.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-119)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14374.51 Da        Isoelectric Point: 5.1094

>T38458 WP_223927621.1 NZ_AP024463:2957290-2957688 [Arachnia rubra]
MIRYLLDANVLIALTAAEHEHHEAAGEWLAETTQFATCPTTESALLRFLLGLGEPATMALERIRLIRALPAAEFWPSDLS
YADIDATGLIGHRQATDLYLVSLAAAHGGLLATFDKALHASRPDLTFLIPRP

Download         Length: 399 bp

>T38458 NZ_AP024463:2957290-2957688 [Arachnia rubra]
ATGATCCGCTATCTCCTGGACGCCAACGTCTTGATAGCCCTCACCGCAGCCGAACACGAACACCATGAGGCCGCAGGTGA
GTGGCTCGCAGAAACCACCCAGTTCGCGACCTGCCCCACCACAGAAAGTGCTCTACTGCGTTTCCTCCTTGGTTTGGGCG
AACCAGCCACCATGGCTCTGGAACGCATCCGGCTCATCAGGGCACTCCCTGCTGCCGAGTTCTGGCCCAGCGACCTGTCA
TACGCCGATATCGACGCCACTGGCCTGATCGGTCACCGCCAAGCCACAGATCTCTATCTCGTCTCCCTGGCTGCCGCGCA
CGGCGGACTCCTCGCCACCTTCGACAAGGCCCTTCATGCCTCCCGACCAGACCTGACCTTTCTGATCCCTCGCCCATAG

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8404.51 Da        Isoelectric Point: 4.5184

>AT38458 WP_212323090.1 NZ_AP024463:2957060-2957293 [Arachnia rubra]
MRTTVDLPPAVRERAQEIAQLQGRSLSAVVAELATRGLAQLDDHPAIIETDPRTGFPVLRIGRSITNEQVADLIEES

Download         Length: 234 bp

>AT38458 NZ_AP024463:2957060-2957293 [Arachnia rubra]
ATGCGCACCACGGTCGATCTACCCCCTGCAGTCCGAGAAAGAGCACAGGAGATAGCTCAACTACAGGGCCGCTCACTATC
AGCCGTCGTAGCAGAGCTGGCGACCCGGGGGCTTGCCCAGCTCGATGACCACCCAGCCATCATCGAAACCGATCCCCGCA
CCGGCTTCCCCGTTCTACGCATTGGCAGATCCATCACAAACGAACAGGTTGCAGACCTCATCGAGGAGTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References