Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 373061..373740 Replicon chromosome
Accession NZ_AP024463
Organism Arachnia rubra strain SK-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SK1NUM_RS01600 Protein ID WP_212324454.1
Coordinates 373309..373740 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SK1NUM_RS01595 Protein ID WP_212324452.1
Coordinates 373061..373309 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SK1NUM_RS01580 (SK1NUM_03160) 368610..370700 - 2091 WP_212324446.1 hypothetical protein -
SK1NUM_RS01585 (SK1NUM_03170) 370787..371176 - 390 WP_212324448.1 nuclear transport factor 2 family protein -
SK1NUM_RS01590 (SK1NUM_03180) 371353..372519 - 1167 WP_212324450.1 hypothetical protein -
SK1NUM_RS01595 (SK1NUM_03200) 373061..373309 + 249 WP_212324452.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
SK1NUM_RS01600 (SK1NUM_03210) 373309..373740 + 432 WP_212324454.1 type II toxin-antitoxin system VapC family toxin Toxin
SK1NUM_RS01605 (SK1NUM_03220) 373850..375130 - 1281 WP_212324456.1 alpha/beta hydrolase -
SK1NUM_RS01610 (SK1NUM_03230) 375358..376212 + 855 WP_223927726.1 hypothetical protein -
SK1NUM_RS01615 (SK1NUM_03240) 376184..376546 + 363 WP_223927728.1 glycosyltransferase -
SK1NUM_RS01620 (SK1NUM_03250) 376543..377742 + 1200 WP_212324460.1 glycosyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-127)

Antitoxin

SpoVT-AbrB domain

(8-53)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 15708.97 Da        Isoelectric Point: 4.9670

>T38455 WP_212324454.1 NZ_AP024463:373309-373740 [Arachnia rubra]
MRYLLDTNIVGQLMRAHPVALERLARHGTDRVFISAITEAEICFGLAKRPAAARLHRAVEVLREQVEVLDFTARTALVYG
SLRADLESSGMPMSPLDTLIAATALEHRQDDADIVLVTSDHAFSRIPGLVVEDWTVEACGEGQ

Download         Length: 432 bp

>T38455 NZ_AP024463:373309-373740 [Arachnia rubra]
ATGCGGTACCTCCTTGACACCAACATTGTTGGCCAGCTCATGCGTGCGCATCCGGTCGCGCTTGAGCGGCTGGCACGTCA
CGGGACTGATCGTGTTTTCATATCCGCTATCACCGAAGCTGAGATCTGCTTCGGCCTGGCGAAGAGGCCGGCTGCGGCCC
GGCTGCATCGTGCGGTGGAGGTGCTGCGGGAGCAAGTCGAGGTGCTGGACTTCACCGCGCGCACCGCTCTGGTCTACGGA
TCACTGCGAGCAGATCTGGAATCATCTGGTATGCCCATGTCGCCTTTGGACACATTGATTGCCGCAACGGCCCTGGAGCA
CAGGCAGGATGACGCGGACATTGTTCTCGTGACAAGCGACCATGCCTTCTCTCGTATCCCGGGACTCGTAGTCGAAGACT
GGACCGTCGAGGCATGCGGCGAAGGGCAGTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9075.94 Da        Isoelectric Point: 4.1705

>AT38455 WP_212324452.1 NZ_AP024463:373061-373309 [Arachnia rubra]
VSQVTTVFKNGGSQAVRIPAAYRFDTDRVYIRRDDNGDVVLSTRPGAWDAFIEAVTGLDVPDDFLAPETRQAEERNLFDG
EG

Download         Length: 249 bp

>AT38455 NZ_AP024463:373061-373309 [Arachnia rubra]
GTGAGCCAGGTTACGACAGTTTTCAAGAACGGCGGATCGCAGGCGGTGCGGATACCCGCCGCGTATCGGTTCGACACCGA
CAGGGTCTACATCAGGCGTGACGACAATGGGGACGTGGTGCTTTCCACTAGGCCTGGTGCGTGGGATGCCTTCATCGAGG
CTGTCACCGGACTGGATGTGCCCGATGACTTCCTTGCGCCAGAGACTCGCCAGGCCGAGGAGCGAAACCTGTTCGACGGG
GAGGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References