Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 250100..250623 Replicon chromosome
Accession NZ_AP024463
Organism Arachnia rubra strain SK-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SK1NUM_RS01025 Protein ID WP_212324214.1
Coordinates 250366..250623 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SK1NUM_RS01020 Protein ID WP_212324212.1
Coordinates 250100..250369 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SK1NUM_RS00990 (SK1NUM_01950) 245172..246134 + 963 WP_212324196.1 bile acid:sodium symporter family protein -
SK1NUM_RS00995 (SK1NUM_01960) 246185..246793 - 609 WP_223927699.1 DJ-1/PfpI family protein -
SK1NUM_RS01000 (SK1NUM_01970) 246978..247946 + 969 WP_212324204.1 hypothetical protein -
SK1NUM_RS01005 (SK1NUM_01980) 247924..248742 + 819 WP_212324206.1 hypothetical protein -
SK1NUM_RS01010 (SK1NUM_01990) 248739..249359 - 621 WP_212324208.1 ribonuclease D -
SK1NUM_RS01015 (SK1NUM_02000) 249523..249879 - 357 WP_212324210.1 hypothetical protein -
SK1NUM_RS01020 (SK1NUM_02010) 250100..250369 + 270 WP_212324212.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
SK1NUM_RS01025 (SK1NUM_02020) 250366..250623 + 258 WP_212324214.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SK1NUM_RS15110 (SK1NUM_02030) 251288..251590 - 303 WP_244980175.1 transposase -
SK1NUM_RS01035 (SK1NUM_02040) 251578..252399 - 822 WP_244980176.1 ISAs1 family transposase -
SK1NUM_RS01040 252550..253317 + 768 WP_223927909.1 IS3 family transposase -
SK1NUM_RS01050 (SK1NUM_02050) 253530..254285 - 756 WP_212323263.1 transposase family protein -
SK1NUM_RS01055 (SK1NUM_02060) 254419..255289 + 871 Protein_207 IS1634 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 236678..259537 22859
- flank IS/Tn - - 255506..255736 230


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(6-72)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9777.25 Da        Isoelectric Point: 10.6715

>T38454 WP_212324214.1 NZ_AP024463:250366-250623 [Arachnia rubra]
MTTPREIAWRPAARRALGRLPEKVATAAIEFVYGPLADNPYRVGKPLRFELEGLHSARRGNYRVIYRSAERIEIIAVEHR
ADAYR

Download         Length: 258 bp

>T38454 NZ_AP024463:250366-250623 [Arachnia rubra]
ATGACCACCCCGCGCGAGATCGCATGGCGTCCGGCGGCTAGACGAGCCCTCGGGAGGCTGCCGGAGAAAGTGGCGACGGC
TGCCATCGAATTCGTCTATGGCCCACTCGCCGATAATCCATATCGGGTTGGCAAGCCGCTTCGTTTTGAGCTGGAGGGGC
TTCACAGTGCGCGCCGCGGCAACTACCGAGTCATCTATCGCAGTGCCGAACGCATCGAGATTATCGCCGTCGAGCACCGG
GCCGACGCCTACCGATAG

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9750.24 Da        Isoelectric Point: 4.6768

>AT38454 WP_212324212.1 NZ_AP024463:250100-250369 [Arachnia rubra]
MSMEQAMPLREVKNRLSEVVDRVAGQHDRVVITRHGRPAAVVLSPDDLASLEETLDVMGCPRLLADIRESLAAEGEVMSK
EEILAALGR

Download         Length: 270 bp

>AT38454 NZ_AP024463:250100-250369 [Arachnia rubra]
ATGAGTATGGAGCAGGCCATGCCTCTCAGGGAGGTCAAGAATCGTCTTTCTGAGGTGGTGGACCGGGTGGCGGGGCAGCA
TGACCGGGTGGTGATCACCCGGCATGGACGACCTGCGGCGGTGGTGCTCAGTCCCGATGATCTGGCCTCTCTTGAGGAGA
CCCTTGACGTCATGGGGTGTCCCAGGCTGCTGGCGGATATCCGGGAGAGCCTGGCTGCCGAGGGCGAGGTCATGTCGAAG
GAGGAAATCCTGGCGGCTCTCGGTCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References