Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/GNAT-DUF1778
Location 2279554..2280341 Replicon chromosome
Accession NZ_AP024452
Organism Luteitalea sp. TBR-22

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag TBR22_RS09320 Protein ID WP_239492703.1
Coordinates 2279832..2280341 (+) Length 170 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag TBR22_RS09315 Protein ID WP_239492702.1
Coordinates 2279554..2279835 (+) Length 94 a.a.

Genomic Context

TBR22_RS09305TBR22_RS09310TBR22_RS09315TBR22_RS09320TBR22_RS09325TBR22_RS09330TBR22_RS09335TBR22_RS09340TBR22_RS09300TBR22_RS09345TBR22_RS09350TBR22_RS09355
Location: 2277008..2278204 (1197 bp)
Type: Others
Protein ID: WP_239492700.1
Location: 2278201..2279157 (957 bp)
Type: Others
Protein ID: WP_239492701.1
Location: 2279554..2279835 (282 bp)
Type: Antitoxin
Protein ID: WP_239492702.1
Location: 2279832..2280341 (510 bp)
Type: Toxin
Protein ID: WP_239492703.1
Location: 2280850..2281200 (351 bp)
Type: Others
Protein ID: WP_239492704.1
Location: 2281190..2281528 (339 bp)
Type: Others
Protein ID: WP_239492705.1
Location: 2281676..2282764 (1089 bp)
Type: Others
Protein ID: WP_239492706.1
Location: 2282761..2283687 (927 bp)
Type: Others
Protein ID: WP_239492707.1
Location: 2276264..2276722 (459 bp)
Type: Others
Protein ID: WP_239492699.1
Location: 2283718..2283981 (264 bp)
Type: Others
Protein ID: WP_239492708.1
Location: 2284565..2284888 (324 bp)
Type: Others
Protein ID: WP_239492709.1
Location: 2284885..2285244 (360 bp)
Type: Others
Protein ID: WP_239492710.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
TBR22_RS09300 (TBR22_18630)2276264..2276722-459WP_239492699.1hypothetical protein-
TBR22_RS09305 (TBR22_18640)2277008..2278204+1197WP_239492700.1hypothetical protein-
TBR22_RS09310 (TBR22_18650)2278201..2279157+957WP_239492701.1VWA domain-containing protein-
TBR22_RS09315 (TBR22_18660)2279554..2279835+282WP_239492702.1DUF1778 domain-containing proteinAntitoxin
TBR22_RS09320 (TBR22_18670)2279832..2280341+510WP_239492703.1GNAT family N-acetyltransferaseToxin
TBR22_RS09325 (TBR22_18680)2280850..2281200+351WP_239492704.1nucleotidyltransferase family protein-
TBR22_RS09330 (TBR22_18690)2281190..2281528+339WP_239492705.1DUF86 domain-containing protein-
TBR22_RS09335 (TBR22_A18870)2281676..2282764+1089WP_239492706.1tetratricopeptide repeat protein-
TBR22_RS09340 (TBR22_A18880)2282761..2283687+927WP_239492707.1VWA domain-containing protein-
TBR22_RS09345 (TBR22_A18890)2283718..2283981-264WP_239492708.1GIY-YIG nuclease family protein-
TBR22_RS09350 (TBR22_18700)2284565..2284888-324WP_239492709.1helix-turn-helix transcriptional regulator-
TBR22_RS09355 (TBR22_18710)2284885..2285244-360WP_239492710.1type II toxin-antitoxin system RelE/ParE family toxin-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(46-148)

Antitoxin

Vibrio phage ICP1, Orf50

(12-86)


Sequences

Toxin        


Download         Length: 170 a.a.        Molecular weight: 18108.88 Da        Isoelectric Point: 9.5927

>T38450 WP_239492703.1 NZ_AP024452:2279832-2280341 [Luteitalea sp. TBR-22]
MNRDADVGAPEHLDAHHDIAAFDSGTPDLDLWLKRRALTNEALGASRTYVVCASGRVVGFYALATGAVAHEAVTGRVRRN
MPDPIPVMVLARLAVDRAYQGRGLGRALLRDALLRTLQAAEIVGIRAVLVHALSPSAKQFYLQAGFTEAPVSPMTLLVTL
TDVAGRVRS

Download         Length: 510 bp

>T38450 NZ_AP024452:2279832-2280341 [Luteitalea sp. TBR-22]
ATGAATCGGGACGCCGACGTGGGCGCTCCAGAGCACCTGGACGCACATCACGACATCGCGGCGTTCGATTCCGGCACGCC
CGATCTGGACCTCTGGTTGAAACGGCGCGCGTTGACCAACGAAGCGCTCGGCGCGTCCCGTACCTACGTCGTCTGCGCAT
CCGGTCGCGTGGTCGGCTTCTATGCCCTGGCCACCGGCGCCGTGGCCCACGAGGCCGTGACCGGGCGCGTGCGGCGGAAC
ATGCCGGATCCGATCCCCGTGATGGTGCTCGCGCGGCTGGCGGTGGACCGGGCCTACCAGGGCCGCGGGCTGGGGCGGGC
GTTGTTGCGCGACGCGCTGCTGCGCACCCTGCAGGCGGCCGAGATTGTGGGCATCCGCGCCGTGCTTGTCCACGCCCTCT
CGCCGTCGGCCAAGCAGTTCTACCTGCAGGCGGGTTTCACGGAGGCCCCGGTGAGTCCGATGACGCTGCTGGTGACGCTG
ACTGACGTGGCAGGTCGCGTACGTTCTTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10359.84 Da        Isoelectric Point: 10.0050

>AT38450 WP_239492702.1 NZ_AP024452:2279554-2279835 [Luteitalea sp. TBR-22]
MANAASCPRTSISLRIPDDQRALIDRAAEASGKDRTAFMLDAATREATTVLLDQRYFRLDADAWATFTALLDARPTPNPR
LKKLLATKAPWER

Download         Length: 282 bp

>AT38450 NZ_AP024452:2279554-2279835 [Luteitalea sp. TBR-22]
ATGGCGAACGCCGCATCCTGCCCGCGCACGAGCATCAGCCTCCGCATTCCCGACGACCAGCGCGCTCTGATCGACCGCGC
CGCTGAGGCGTCCGGCAAGGACCGCACCGCGTTCATGCTCGACGCCGCGACCCGCGAGGCGACGACCGTGCTGCTCGATC
AACGCTATTTCCGGCTGGACGCGGATGCGTGGGCCACGTTCACGGCCCTGCTGGATGCGCGGCCGACGCCGAACCCGCGG
CTCAAGAAACTGCTGGCTACCAAAGCCCCTTGGGAGCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References