Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 774386..775053 Replicon chromosome
Accession NZ_AP024452
Organism Luteitalea sp. TBR-22

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag TBR22_RS03120 Protein ID WP_239491493.1
Coordinates 774631..775053 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag TBR22_RS03115 Protein ID WP_239491492.1
Coordinates 774386..774631 (+) Length 82 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TBR22_RS03105 (TBR22_06290) 769542..770300 - 759 WP_239491490.1 hypothetical protein -
TBR22_RS03110 (TBR22_06300) 771686..774253 + 2568 WP_239491491.1 DEAD/DEAH box helicase -
TBR22_RS03115 (TBR22_06310) 774386..774631 + 246 WP_239491492.1 antitoxin Antitoxin
TBR22_RS03120 (TBR22_06320) 774631..775053 + 423 WP_239491493.1 type II toxin-antitoxin system VapC family toxin Toxin
TBR22_RS03125 (TBR22_06330) 775143..775565 + 423 WP_239491494.1 DUF4174 domain-containing protein -
TBR22_RS03130 (TBR22_06340) 775611..777542 - 1932 WP_239491495.1 asparagine synthase (glutamine-hydrolyzing) -
TBR22_RS03135 (TBR22_06350) 777744..778493 - 750 WP_239491496.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-122)

Antitoxin

(7-44)


Sequences


Toxin        


Download         Length: 141 a.a.        Molecular weight: 15706.90 Da        Isoelectric Point: 10.7511

>T38448 WP_239491493.1 NZ_AP024452:774631-775053 [Luteitalea sp. TBR-22]
MRYLLDANAVIALLNDTTSPIARRVRRHAPREFGVSAIVIHELYYGAYKSQRVEQNVARVDALRFSVLEFDDEDARQAGQ
IRAHLASKGTPIGPFDVLIAGQARARGLTLVTHNTSEFQRVPGLIVEDWKAVTRQRRGRA

Download         Length: 423 bp

>T38448 NZ_AP024452:774631-775053 [Luteitalea sp. TBR-22]
ATGCGGTATCTCCTCGACGCGAACGCCGTCATCGCGTTGTTGAACGACACGACCTCGCCGATCGCCAGGCGTGTCCGTCG
CCATGCGCCTCGCGAGTTCGGGGTGTCGGCGATTGTCATCCACGAGTTGTACTACGGGGCGTACAAGAGTCAGCGGGTGG
AGCAGAACGTCGCCCGCGTGGACGCGCTCCGGTTCTCGGTGTTGGAGTTCGACGACGAGGACGCCCGTCAGGCGGGCCAG
ATCAGGGCCCACCTCGCGTCGAAAGGAACGCCGATCGGCCCCTTCGACGTGTTGATCGCTGGCCAGGCCAGGGCACGCGG
GCTGACGCTCGTCACCCACAACACGAGCGAGTTCCAGCGAGTGCCCGGGTTGATCGTAGAGGACTGGAAGGCTGTCACTC
GACAGCGCCGTGGCCGGGCATGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9233.39 Da        Isoelectric Point: 6.3483

>AT38448 WP_239491492.1 NZ_AP024452:774386-774631 [Luteitalea sp. TBR-22]
VDTAKVFWSGRSQAVRLPRAFRVDAGEVRIRRRGRAIVLEPVPESWEWLDALVGNVDDDFASAVREEPDAPERRGLSQVF
R

Download         Length: 246 bp

>AT38448 NZ_AP024452:774386-774631 [Luteitalea sp. TBR-22]
GTGGACACCGCCAAGGTCTTCTGGTCCGGTCGCTCGCAGGCGGTGCGGTTGCCGCGTGCCTTTCGCGTCGATGCCGGTGA
GGTTCGTATCCGGCGCCGCGGGCGCGCGATCGTGCTGGAACCGGTTCCCGAGTCATGGGAGTGGCTCGATGCGCTCGTCG
GCAACGTCGACGATGACTTTGCGTCAGCGGTGCGGGAGGAGCCGGATGCGCCGGAGCGTCGCGGGTTGAGCCAGGTGTTC
CGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References