Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 774386..775053 | Replicon | chromosome |
| Accession | NZ_AP024452 | ||
| Organism | Luteitalea sp. TBR-22 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | TBR22_RS03120 | Protein ID | WP_239491493.1 |
| Coordinates | 774631..775053 (+) | Length | 141 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | TBR22_RS03115 | Protein ID | WP_239491492.1 |
| Coordinates | 774386..774631 (+) | Length | 82 a.a. |
Genomic Context
Location: 771686..774253 (2568 bp)
Type: Others
Protein ID: WP_239491491.1
Type: Others
Protein ID: WP_239491491.1
Location: 774386..774631 (246 bp)
Type: Antitoxin
Protein ID: WP_239491492.1
Type: Antitoxin
Protein ID: WP_239491492.1
Location: 774631..775053 (423 bp)
Type: Toxin
Protein ID: WP_239491493.1
Type: Toxin
Protein ID: WP_239491493.1
Location: 775143..775565 (423 bp)
Type: Others
Protein ID: WP_239491494.1
Type: Others
Protein ID: WP_239491494.1
Location: 769542..770300 (759 bp)
Type: Others
Protein ID: WP_239491490.1
Type: Others
Protein ID: WP_239491490.1
Location: 775611..777542 (1932 bp)
Type: Others
Protein ID: WP_239491495.1
Type: Others
Protein ID: WP_239491495.1
Location: 777744..778493 (750 bp)
Type: Others
Protein ID: WP_239491496.1
Type: Others
Protein ID: WP_239491496.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| TBR22_RS03105 (TBR22_06290) | 769542..770300 | - | 759 | WP_239491490.1 | hypothetical protein | - |
| TBR22_RS03110 (TBR22_06300) | 771686..774253 | + | 2568 | WP_239491491.1 | DEAD/DEAH box helicase | - |
| TBR22_RS03115 (TBR22_06310) | 774386..774631 | + | 246 | WP_239491492.1 | antitoxin | Antitoxin |
| TBR22_RS03120 (TBR22_06320) | 774631..775053 | + | 423 | WP_239491493.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| TBR22_RS03125 (TBR22_06330) | 775143..775565 | + | 423 | WP_239491494.1 | DUF4174 domain-containing protein | - |
| TBR22_RS03130 (TBR22_06340) | 775611..777542 | - | 1932 | WP_239491495.1 | asparagine synthase (glutamine-hydrolyzing) | - |
| TBR22_RS03135 (TBR22_06350) | 777744..778493 | - | 750 | WP_239491496.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 141 a.a. Molecular weight: 15706.90 Da Isoelectric Point: 10.7511
>T38448 WP_239491493.1 NZ_AP024452:774631-775053 [Luteitalea sp. TBR-22]
MRYLLDANAVIALLNDTTSPIARRVRRHAPREFGVSAIVIHELYYGAYKSQRVEQNVARVDALRFSVLEFDDEDARQAGQ
IRAHLASKGTPIGPFDVLIAGQARARGLTLVTHNTSEFQRVPGLIVEDWKAVTRQRRGRA
MRYLLDANAVIALLNDTTSPIARRVRRHAPREFGVSAIVIHELYYGAYKSQRVEQNVARVDALRFSVLEFDDEDARQAGQ
IRAHLASKGTPIGPFDVLIAGQARARGLTLVTHNTSEFQRVPGLIVEDWKAVTRQRRGRA
Download Length: 423 bp
>T38448 NZ_AP024452:774631-775053 [Luteitalea sp. TBR-22]
ATGCGGTATCTCCTCGACGCGAACGCCGTCATCGCGTTGTTGAACGACACGACCTCGCCGATCGCCAGGCGTGTCCGTCG
CCATGCGCCTCGCGAGTTCGGGGTGTCGGCGATTGTCATCCACGAGTTGTACTACGGGGCGTACAAGAGTCAGCGGGTGG
AGCAGAACGTCGCCCGCGTGGACGCGCTCCGGTTCTCGGTGTTGGAGTTCGACGACGAGGACGCCCGTCAGGCGGGCCAG
ATCAGGGCCCACCTCGCGTCGAAAGGAACGCCGATCGGCCCCTTCGACGTGTTGATCGCTGGCCAGGCCAGGGCACGCGG
GCTGACGCTCGTCACCCACAACACGAGCGAGTTCCAGCGAGTGCCCGGGTTGATCGTAGAGGACTGGAAGGCTGTCACTC
GACAGCGCCGTGGCCGGGCATGA
ATGCGGTATCTCCTCGACGCGAACGCCGTCATCGCGTTGTTGAACGACACGACCTCGCCGATCGCCAGGCGTGTCCGTCG
CCATGCGCCTCGCGAGTTCGGGGTGTCGGCGATTGTCATCCACGAGTTGTACTACGGGGCGTACAAGAGTCAGCGGGTGG
AGCAGAACGTCGCCCGCGTGGACGCGCTCCGGTTCTCGGTGTTGGAGTTCGACGACGAGGACGCCCGTCAGGCGGGCCAG
ATCAGGGCCCACCTCGCGTCGAAAGGAACGCCGATCGGCCCCTTCGACGTGTTGATCGCTGGCCAGGCCAGGGCACGCGG
GCTGACGCTCGTCACCCACAACACGAGCGAGTTCCAGCGAGTGCCCGGGTTGATCGTAGAGGACTGGAAGGCTGTCACTC
GACAGCGCCGTGGCCGGGCATGA
Antitoxin
Download Length: 82 a.a. Molecular weight: 9233.39 Da Isoelectric Point: 6.3483
>AT38448 WP_239491492.1 NZ_AP024452:774386-774631 [Luteitalea sp. TBR-22]
VDTAKVFWSGRSQAVRLPRAFRVDAGEVRIRRRGRAIVLEPVPESWEWLDALVGNVDDDFASAVREEPDAPERRGLSQVF
R
VDTAKVFWSGRSQAVRLPRAFRVDAGEVRIRRRGRAIVLEPVPESWEWLDALVGNVDDDFASAVREEPDAPERRGLSQVF
R
Download Length: 246 bp
>AT38448 NZ_AP024452:774386-774631 [Luteitalea sp. TBR-22]
GTGGACACCGCCAAGGTCTTCTGGTCCGGTCGCTCGCAGGCGGTGCGGTTGCCGCGTGCCTTTCGCGTCGATGCCGGTGA
GGTTCGTATCCGGCGCCGCGGGCGCGCGATCGTGCTGGAACCGGTTCCCGAGTCATGGGAGTGGCTCGATGCGCTCGTCG
GCAACGTCGACGATGACTTTGCGTCAGCGGTGCGGGAGGAGCCGGATGCGCCGGAGCGTCGCGGGTTGAGCCAGGTGTTC
CGCTGA
GTGGACACCGCCAAGGTCTTCTGGTCCGGTCGCTCGCAGGCGGTGCGGTTGCCGCGTGCCTTTCGCGTCGATGCCGGTGA
GGTTCGTATCCGGCGCCGCGGGCGCGCGATCGTGCTGGAACCGGTTCCCGAGTCATGGGAGTGGCTCGATGCGCTCGTCG
GCAACGTCGACGATGACTTTGCGTCAGCGGTGCGGGAGGAGCCGGATGCGCCGGAGCGTCGCGGGTTGAGCCAGGTGTTC
CGCTGA