Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 75840..76516 Replicon chromosome
Accession NZ_AP024452
Organism Luteitalea sp. TBR-22

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag TBR22_RS00315 Protein ID WP_239490952.1
Coordinates 75840..76271 (-) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag TBR22_RS00320 Protein ID WP_239490953.1
Coordinates 76271..76516 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TBR22_RS00305 (TBR22_00590) 70909..74145 + 3237 WP_239490950.1 amidohydrolase family protein -
TBR22_RS00310 (TBR22_00600) 74222..75733 - 1512 WP_239490951.1 sulfatase -
TBR22_RS00315 (TBR22_00610) 75840..76271 - 432 WP_239490952.1 PIN domain-containing protein Toxin
TBR22_RS00320 76271..76516 - 246 WP_239490953.1 CopG family transcriptional regulator Antitoxin
TBR22_RS00325 (TBR22_00630) 76735..78753 - 2019 WP_239490954.1 hypothetical protein -
TBR22_RS00330 (TBR22_00640) 78832..79347 - 516 WP_239490955.1 response regulator transcription factor -
TBR22_RS00335 (TBR22_00650) 79509..81455 - 1947 WP_239490956.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(2-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 15435.60 Da        Isoelectric Point: 6.8816

>T38447 WP_239490952.1 NZ_AP024452:c76271-75840 [Luteitalea sp. TBR-22]
MRGLLDVNVLIALLDAAHVHHHLASRWLADHIGHGWASCPLTQLGCIRVMAQSAYPNMQPAAQVAERLQAAAATPHHEFW
SADTDLLAADTVRWSELLTSRHATDAYLLALAAARGGRFVTFDQHVPLRAVPSADAGHLTVIG

Download         Length: 432 bp

>T38447 NZ_AP024452:c76271-75840 [Luteitalea sp. TBR-22]
ATGCGGGGGTTACTCGACGTCAACGTCCTGATCGCGCTGCTCGACGCGGCACACGTCCACCACCACCTGGCGAGCCGGTG
GCTGGCCGATCACATCGGGCACGGCTGGGCCTCCTGCCCGCTCACGCAGCTCGGCTGCATCCGGGTGATGGCGCAGTCGG
CATATCCGAACATGCAGCCGGCCGCACAGGTCGCCGAGCGCCTGCAGGCCGCGGCCGCAACGCCCCACCACGAGTTCTGG
AGCGCCGACACCGACCTGCTCGCGGCCGACACCGTCCGCTGGTCGGAGCTGTTGACCTCGCGCCACGCCACCGACGCCTA
CCTGCTCGCACTCGCAGCCGCGCGGGGCGGGCGCTTCGTGACCTTCGACCAGCACGTACCGCTGCGCGCCGTACCGTCGG
CAGACGCAGGGCACCTGACGGTGATCGGCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8860.21 Da        Isoelectric Point: 4.7730

>AT38447 WP_239490953.1 NZ_AP024452:c76516-76271 [Luteitalea sp. TBR-22]
MRTTLDIEDDVLAAVKALARKEGLTAGEMLSLLARRALTSPPAELGDIRDRPVVFGFRPFPPGKTLVTNEVIDDLRDRDG
V

Download         Length: 246 bp

>AT38447 NZ_AP024452:c76516-76271 [Luteitalea sp. TBR-22]
ATGCGAACCACTCTCGACATCGAAGACGACGTGTTGGCGGCGGTGAAGGCGCTTGCGAGGAAAGAGGGCCTGACCGCCGG
CGAGATGCTGTCGTTGCTCGCGCGACGGGCCCTCACCAGCCCGCCGGCCGAACTCGGCGACATCCGCGACAGGCCCGTCG
TCTTCGGATTCCGCCCCTTTCCGCCGGGCAAGACGCTCGTCACCAACGAGGTCATCGACGACCTGCGCGACCGCGACGGG
GTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References