Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 839182..839840 Replicon chromosome
Accession NZ_AP024355
Organism Desulfuromonas versatilis strain NIT-T3

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag DESUT3_RS03660 Protein ID WP_225911611.1
Coordinates 839182..839508 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag DESUT3_RS03665 Protein ID WP_221251115.1
Coordinates 839505..839840 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DESUT3_RS03650 (DESUT3_07180) 837347..838291 + 945 WP_225911610.1 EamA family transporter RarD -
DESUT3_RS03655 (DESUT3_07190) 838378..839025 + 648 WP_221251114.1 hypothetical protein -
DESUT3_RS03660 (DESUT3_07200) 839182..839508 + 327 WP_225911611.1 type II toxin-antitoxin system HicA family toxin Toxin
DESUT3_RS03665 (DESUT3_07210) 839505..839840 + 336 WP_221251115.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
DESUT3_RS03670 (DESUT3_07220) 840145..840435 - 291 WP_221251116.1 GYD domain-containing protein -
DESUT3_RS03675 (DESUT3_07230) 840484..840981 - 498 WP_221251117.1 ferritin family protein -
DESUT3_RS03680 (DESUT3_07240) 841144..841620 + 477 WP_221251118.1 DUF4112 domain-containing protein -
DESUT3_RS21095 841662..841919 + 258 WP_264082186.1 GSU3128 family (seleno)protein -
DESUT3_RS03690 (DESUT3_07250) 842716..843639 - 924 WP_221251120.1 DMT family transporter -
DESUT3_RS03695 (DESUT3_07260) 843621..844580 - 960 WP_221251121.1 DMT family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(47-102)

Antitoxin

Uncharacterised protein family HicB

(55-105)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12378.10 Da        Isoelectric Point: 9.8587

>T38436 WP_225911611.1 NZ_AP024355:839182-839508 [Desulfuromonas versatilis]
VFGAQPFFSNPPLDDSTTIRYHSFIKRKHQKTLELIFARPVSANIKWRDIEALLVELGAEITEREGSRIGVRLFGDRRVF
HRPHPSPDTDKGAVAAIRDWLKENEVTP

Download         Length: 327 bp

>T38436 NZ_AP024355:839182-839508 [Desulfuromonas versatilis]
GTGTTCGGCGCGCAACCGTTCTTCTCGAACCCCCCCCTTGACGACAGTACCACTATCCGGTACCATTCTTTCATTAAACG
CAAGCACCAGAAAACCCTTGAGCTTATTTTCGCCCGGCCGGTCAGCGCCAACATCAAGTGGCGCGACATCGAGGCGCTGC
TGGTTGAACTCGGCGCCGAAATAACCGAGCGCGAAGGTTCGCGCATAGGGGTCAGGCTGTTCGGCGACCGCCGGGTGTTT
CATCGCCCGCATCCATCGCCCGACACCGACAAAGGCGCCGTTGCCGCCATCCGCGACTGGCTCAAAGAAAACGAGGTGAC
ACCATGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12207.94 Da        Isoelectric Point: 5.1882

>AT38436 WP_221251115.1 NZ_AP024355:839505-839840 [Desulfuromonas versatilis]
MMNMMEIDGYRAVIAYDPEIEMFRGEFVGLNGGADFYAKDADGLKKEGAASLKVFLDMCAEDGVNPRKEYSGKFNVRVPG
KLHADIARAAAAHGKSLNQWVVEVLDKAVHE

Download         Length: 336 bp

>AT38436 NZ_AP024355:839505-839840 [Desulfuromonas versatilis]
ATGATGAACATGATGGAAATCGACGGTTACCGCGCCGTCATCGCCTACGACCCGGAAATCGAAATGTTTCGCGGCGAATT
CGTCGGCCTGAACGGCGGCGCCGATTTTTACGCCAAAGACGCCGACGGCCTTAAAAAAGAAGGAGCCGCCTCTCTCAAGG
TCTTTCTCGACATGTGCGCCGAAGACGGGGTCAACCCCAGAAAAGAATACTCCGGCAAATTCAACGTCCGCGTCCCCGGC
AAGCTGCACGCCGACATCGCCCGGGCCGCCGCCGCCCACGGGAAAAGCCTCAATCAGTGGGTGGTTGAAGTCCTGGATAA
AGCCGTGCACGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References