Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 3993457..3994004 Replicon chromosome
Accession NZ_AP024354
Organism Pseudomonas alcaligenes strain KAM426

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JUH08_RS19275 Protein ID WP_061194819.1
Coordinates 3993729..3994004 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JUH08_RS19270 Protein ID WP_061194820.1
Coordinates 3993457..3993729 (+) Length 91 a.a.

Genomic Context

JUH08_RS19250JUH08_RS19255JUH08_RS19260JUH08_RS19265JUH08_RS19270JUH08_RS19275JUH08_RS19280JUH08_RS19285JUH08_RS19290JUH08_RS19295JUH08_RS19300JUH08_RS19240JUH08_RS19245
Location: 3991368..3992138 (771 bp)
Type: Others
Protein ID: WP_061198833.1
Location: 3992158..3992427 (270 bp)
Type: Others
Protein ID: WP_061194823.1
Location: 3992443..3992892 (450 bp)
Type: Others
Protein ID: WP_061199210.1
Location: 3992889..3993473 (585 bp)
Type: Others
Protein ID: WP_061194821.1
Location: 3993457..3993729 (273 bp)
Type: Antitoxin
Protein ID: WP_061194820.1
Location: 3993729..3994004 (276 bp)
Type: Toxin
Protein ID: WP_061194819.1
Location: 3994006..3994833 (828 bp)
Type: Others
Protein ID: WP_061194818.1
Location: 3994847..3995089 (243 bp)
Type: Others
Protein ID: WP_203787088.1
Location: 3995144..3995389 (246 bp)
Type: Others
Protein ID: WP_061194816.1
Location: 3995564..3996766 (1203 bp)
Type: Others
Protein ID: WP_203788698.1
Location: 3996751..3998292 (1542 bp)
Type: Others
Protein ID: WP_203788700.1
Location: 3990227..3990745 (519 bp)
Type: Others
Protein ID: WP_203792471.1
Location: 3990858..3991082 (225 bp)
Type: Others
Protein ID: Protein_3777
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JUH08_RS192403990227..3990745-519WP_203792471.1peptide-methionine (S)-S-oxide reductase MsrA-
JUH08_RS192453990858..3991082-225Protein_3777helix-turn-helix domain-containing protein-
JUH08_RS192503991368..3992138+771WP_061198833.1DUF2807 domain-containing protein-
JUH08_RS192553992158..3992427+270WP_061194823.1hypothetical protein-
JUH08_RS192603992443..3992892+450WP_061199210.1hypothetical protein-
JUH08_RS192653992889..3993473+585WP_061194821.1hypothetical protein-
JUH08_RS192703993457..3993729+273WP_061194820.1ribbon-helix-helix domain-containing proteinAntitoxin
JUH08_RS192753993729..3994004+276WP_061194819.1type II toxin-antitoxin system RelE/ParE family toxinToxin
JUH08_RS192803994006..3994833+828WP_061194818.1hypothetical protein-
JUH08_RS192853994847..3995089+243WP_203787088.1hypothetical protein-
JUH08_RS192903995144..3995389+246WP_061194816.1hypothetical protein-
JUH08_RS192953995564..3996766+1203WP_203788698.1hypothetical protein-
JUH08_RS193003996751..3998292+1542WP_203788700.1Hsp70 family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic islandsul1 / blaIMP-1-3786007..4015023229016


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10673.22 Da        Isoelectric Point: 7.2020

>T38435 WP_061194819.1 NZ_AP024354:3993729-3994004 [Pseudomonas alcaligenes]
MELKWTSKALSDLARLYEFLAAVNQPAAARTVQQLTAAPTTLLTNPRIGERLEEFDPRDVRRILVGHYEMRYEIADSTIY
LLRLWHTREDR

Download         Length: 276 bp

>T38435 NZ_AP024354:3993729-3994004 [Pseudomonas alcaligenes]
ATGGAGTTGAAGTGGACGAGCAAGGCCCTATCCGATCTGGCCCGCCTCTATGAGTTCCTTGCAGCGGTGAACCAGCCCGC
TGCGGCGCGCACAGTGCAGCAGCTCACCGCAGCGCCGACGACGCTGCTGACCAACCCGCGCATCGGCGAGCGGCTGGAAG
AGTTCGATCCGCGCGACGTGCGACGGATTCTGGTCGGGCACTACGAGATGCGCTACGAAATAGCAGACTCCACCATCTAC
CTGCTGCGCCTGTGGCATACACGCGAGGATCGCTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10054.25 Da        Isoelectric Point: 4.8616

>AT38435 WP_061194820.1 NZ_AP024354:3993457-3993729 [Pseudomonas alcaligenes]
MAATAKTRSVTAHVPVELAERVDEIAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSL
STDTPLPVPH

Download         Length: 273 bp

>AT38435 NZ_AP024354:3993457-3993729 [Pseudomonas alcaligenes]
ATGGCCGCAACAGCTAAAACCCGATCCGTCACCGCCCACGTCCCTGTAGAGCTGGCCGAACGTGTTGATGAGATTGCCGA
GCGCCTGGAGCGCTCCAAGAACTGGATCGTCAAGCAAGCCCTGTCCGCCTGGATCGACCAGGAAGAAGAGCGCAGCCGCC
TGACCCGCGAGGCTCTGGCCGATGTGGATGCCGGCCGCGTGATCGACCATCAGGCCGTCCAGGCCTGGGCCGACAGCCTG
AGCACAGACACCCCGCTGCCGGTACCGCACTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References