Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 3865731..3866424 Replicon chromosome
Accession NZ_AP024354
Organism Pseudomonas alcaligenes strain KAM426

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag JUH08_RS18600 Protein ID WP_203788600.1
Coordinates 3866047..3866424 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag JUH08_RS18595 Protein ID WP_203788597.1
Coordinates 3865731..3866066 (-) Length 112 a.a.

Genomic Context

JUH08_RS18555JUH08_RS18605JUH08_RS18610JUH08_RS18560JUH08_RS18565JUH08_RS18570JUH08_RS18575JUH08_RS18580JUH08_RS18585JUH08_RS18590JUH08_RS18595JUH08_RS18600JUH08_RS18615JUH08_RS18620JUH08_RS18625JUH08_RS18630
Location: 3860737..3861435 (699 bp)
Type: Others
Protein ID: WP_203788589.1
Location: 3866616..3867218 (603 bp)
Type: Others
Protein ID: WP_010465829.1
Location: 3867202..3869889 (2688 bp)
Type: Others
Protein ID: Protein_3650
Location: 3861509..3862240 (732 bp)
Type: Others
Protein ID: WP_203788591.1
Location: 3862431..3862979 (549 bp)
Type: Others
Protein ID: WP_203788593.1
Location: 3863248..3864162 (915 bp)
Type: Others
Protein ID: WP_001736514.1
Location: 3864201..3864536 (336 bp)
Type: Others
Protein ID: WP_203788595.1
Location: 3864654..3865034 (381 bp)
Type: Others
Protein ID: WP_001054412.1
Location: 3865031..3865357 (327 bp)
Type: Others
Protein ID: WP_000091614.1
Location: 3865381..3865716 (336 bp)
Type: Others
Protein ID: WP_000741275.1
Location: 3865731..3866066 (336 bp)
Type: Antitoxin
Protein ID: WP_203788597.1
Location: 3866047..3866424 (378 bp)
Type: Toxin
Protein ID: WP_203788600.1
Location: 3869939..3870202 (264 bp)
Type: Others
Protein ID: WP_171953601.1
Location: 3870205..3870480 (276 bp)
Type: Others
Protein ID: WP_116803468.1
Location: 3870480..3870752 (273 bp)
Type: Others
Protein ID: WP_061194820.1
Location: 3870736..3871320 (585 bp)
Type: Others
Protein ID: WP_061194821.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JUH08_RS185553860737..3861435+699WP_203788589.1DNA-binding protein-
JUH08_RS185603861509..3862240-732WP_203788591.1TonB C-terminal domain-containing protein-
JUH08_RS185653862431..3862979-549WP_203788593.1hypothetical protein-
JUH08_RS185703863248..3864162-915WP_001736514.1HD domain-containing protein-
JUH08_RS185753864201..3864536-336WP_203788595.1DUF3391 domain-containing protein-
JUH08_RS185803864654..3865034-381WP_001054412.1hypothetical protein-
JUH08_RS185853865031..3865357-327WP_000091614.1hypothetical protein-
JUH08_RS185903865381..3865716-336WP_000741275.1hypothetical protein-
JUH08_RS185953865731..3866066-336WP_203788597.1helix-turn-helix domain-containing proteinAntitoxin
JUH08_RS186003866047..3866424-378WP_203788600.1type II toxin-antitoxin system RelE/ParE family toxinToxin
JUH08_RS186053866616..3867218+603WP_010465829.1recombinase family protein-
JUH08_RS186103867202..3869889+2688Protein_3650Tn3 family transposase-
JUH08_RS186153869939..3870202-264WP_171953601.1hypothetical protein-
JUH08_RS186203870205..3870480-276WP_116803468.1type II toxin-antitoxin system RelE/ParE family toxin-
JUH08_RS186253870480..3870752-273WP_061194820.1ribbon-helix-helix domain-containing protein-
JUH08_RS186303870736..3871320-585WP_061194821.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic islandsul1 / blaIMP-1-3786007..4015023229016


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-109)

Antitoxin

Cro/C1-type helix-turn-helix domain

(40-93)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13792.92 Da        Isoelectric Point: 9.7862

>T38433 WP_203788600.1 NZ_AP024354:c3866424-3866047 [Pseudomonas alcaligenes]
MTNKEKPLEWIASSHKDLMALPSDVRRRFGYALSLAQIGDQDDAAKVLKGFGGAGVLEVVEDDAGGTYRAVYTVKFAEAM
FVLHCFQKKSKSGIATPKADMDIIRARLKVAEVLAQELRNAKRNH

Download         Length: 378 bp

>T38433 NZ_AP024354:c3866424-3866047 [Pseudomonas alcaligenes]
ATGACAAACAAAGAAAAACCGCTCGAATGGATCGCGAGCAGCCACAAGGATTTGATGGCGTTGCCGTCCGACGTGCGTCG
CCGTTTCGGTTACGCGCTCTCGTTGGCGCAGATAGGCGATCAGGATGACGCAGCAAAGGTGCTCAAGGGGTTCGGTGGTG
CCGGCGTGCTGGAGGTCGTCGAAGACGATGCCGGCGGCACCTATCGAGCGGTATACACGGTCAAGTTTGCGGAAGCGATG
TTCGTCCTGCACTGCTTCCAGAAGAAGAGCAAGAGCGGAATCGCCACGCCAAAGGCCGACATGGACATCATCCGCGCTCG
GCTGAAGGTGGCCGAGGTATTGGCACAGGAGCTACGAAATGCAAAAAGGAATCATTGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12102.25 Da        Isoelectric Point: 10.3997

>AT38433 WP_203788597.1 NZ_AP024354:c3866066-3865731 [Pseudomonas alcaligenes]
MQKGIIEGVEVQRSSGNVFADLGLPDAEKLKIKTGLVVEIRRAMRALGLTQQAAAKRMGIPQPKVSGMMRGDFTNLSERK
LMDCLNRLGYDIEIKVRPAAEPIGHLTLATA

Download         Length: 336 bp

>AT38433 NZ_AP024354:c3866066-3865731 [Pseudomonas alcaligenes]
ATGCAAAAAGGAATCATTGAAGGCGTCGAGGTTCAGCGCAGCTCGGGCAACGTCTTTGCCGACCTTGGACTGCCTGACGC
TGAAAAGCTCAAGATCAAGACCGGCCTGGTGGTCGAGATCAGGAGGGCCATGCGCGCCCTTGGGCTGACTCAACAAGCGG
CGGCCAAACGCATGGGCATCCCGCAACCGAAGGTGTCGGGCATGATGCGCGGCGACTTCACCAATCTATCCGAACGCAAG
CTGATGGATTGTCTGAATCGCCTCGGCTACGACATCGAAATCAAGGTACGGCCAGCAGCCGAGCCGATCGGGCATCTAAC
GCTCGCAACCGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References