Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 1464415..1465632 | Replicon | chromosome |
Accession | NZ_AP024354 | ||
Organism | Pseudomonas alcaligenes strain KAM426 |
Toxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | JUH08_RS07085 | Protein ID | WP_203791758.1 |
Coordinates | 1464880..1465632 (+) | Length | 251 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | JUH08_RS07080 | Protein ID | WP_203791757.1 |
Coordinates | 1464415..1464786 (+) | Length | 124 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JUH08_RS07060 | 1459840..1460919 | - | 1080 | WP_203791753.1 | ACR3 family arsenite efflux transporter | - |
JUH08_RS07065 | 1461025..1461807 | + | 783 | WP_203791754.1 | metalloregulator ArsR/SmtB family transcription factor | - |
JUH08_RS07070 | 1461864..1462868 | + | 1005 | WP_203791755.1 | ArsJ-associated glyceraldehyde-3-phosphate dehydrogenase | - |
JUH08_RS07075 | 1462878..1464101 | + | 1224 | WP_203791756.1 | organoarsenical effux MFS transporter ArsJ | - |
JUH08_RS07080 | 1464415..1464786 | + | 372 | WP_203791757.1 | DUF2384 domain-containing protein | Antitoxin |
JUH08_RS07085 | 1464880..1465632 | + | 753 | WP_203791758.1 | RES family NAD+ phosphorylase | Toxin |
JUH08_RS07090 | 1465633..1466097 | - | 465 | WP_203791759.1 | copper chaperone PCu(A)C | - |
JUH08_RS07095 | 1466596..1467009 | + | 414 | WP_021701970.1 | sel1 repeat family protein | - |
JUH08_RS07100 | 1467190..1468551 | + | 1362 | WP_203792355.1 | DNA recombination protein RmuC | - |
JUH08_RS07105 | 1468553..1469809 | - | 1257 | WP_203791760.1 | MgtC/SapB family protein | - |
JUH08_RS07110 | 1469878..1470576 | - | 699 | WP_203791761.1 | pirin-like bicupin family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 251 a.a. Molecular weight: 28321.28 Da Isoelectric Point: 7.0302
>T38430 WP_203791758.1 NZ_AP024354:1464880-1465632 [Pseudomonas alcaligenes]
MDIWQACAGVEQIIPLRGRLVRLVENQGQVATLQLVDTLEEQALLEQLLESSKPPLPPGDEPLHYLLRTPFRYPPLRWGS
RFGRRHEPSLFYAACRLETAMAETAFYRFVLWYGMVEPPPSGRILSEHSSFEARYQVQRGVRLQLPPFDGHRALLTHRSD
YRATHSLGSAMREAGVEAFEYPSARCPQGGNNVALYAPTAFSEKRPRNLQPWLCETTAGYVAFKNAQAPDTPRLYALDLY
LEDGVLPQPP
MDIWQACAGVEQIIPLRGRLVRLVENQGQVATLQLVDTLEEQALLEQLLESSKPPLPPGDEPLHYLLRTPFRYPPLRWGS
RFGRRHEPSLFYAACRLETAMAETAFYRFVLWYGMVEPPPSGRILSEHSSFEARYQVQRGVRLQLPPFDGHRALLTHRSD
YRATHSLGSAMREAGVEAFEYPSARCPQGGNNVALYAPTAFSEKRPRNLQPWLCETTAGYVAFKNAQAPDTPRLYALDLY
LEDGVLPQPP
Download Length: 753 bp
>T38430 NZ_AP024354:1464880-1465632 [Pseudomonas alcaligenes]
ATGGATATCTGGCAGGCCTGTGCCGGCGTAGAGCAGATCATTCCCCTGCGCGGCCGCCTGGTGCGCCTGGTCGAGAACCA
GGGCCAGGTGGCGACTCTGCAGCTGGTGGATACGCTGGAGGAGCAGGCGCTGCTCGAACAGTTGCTGGAGAGCAGCAAGC
CGCCGCTGCCGCCCGGTGACGAGCCGCTGCACTACCTGTTGCGCACGCCGTTTCGCTACCCGCCGCTGCGCTGGGGCTCG
CGTTTCGGCCGGCGCCATGAGCCGAGCCTGTTCTACGCCGCCTGCCGGCTGGAGACGGCGATGGCCGAGACCGCCTTCTA
TCGTTTCGTGCTGTGGTACGGCATGGTCGAGCCGCCGCCGAGCGGGCGCATCCTTTCCGAGCATTCGTCCTTCGAGGCGC
GCTACCAGGTGCAGCGCGGGGTGCGCCTGCAGCTACCGCCATTCGACGGCCATCGCGCGCTGCTGACCCATCGCAGTGAC
TATCGCGCCACCCACAGCCTGGGAAGCGCGATGCGCGAAGCGGGGGTGGAAGCGTTCGAGTATCCCTCGGCGCGCTGCCC
GCAGGGGGGCAACAACGTTGCCCTGTATGCGCCGACGGCGTTCAGCGAGAAGCGGCCGCGCAACCTGCAGCCGTGGCTAT
GCGAAACCACCGCAGGCTACGTGGCTTTCAAGAACGCCCAGGCGCCTGATACACCGCGCCTGTACGCCCTTGATCTGTAT
CTCGAGGATGGCGTGCTGCCGCAGCCACCCTGA
ATGGATATCTGGCAGGCCTGTGCCGGCGTAGAGCAGATCATTCCCCTGCGCGGCCGCCTGGTGCGCCTGGTCGAGAACCA
GGGCCAGGTGGCGACTCTGCAGCTGGTGGATACGCTGGAGGAGCAGGCGCTGCTCGAACAGTTGCTGGAGAGCAGCAAGC
CGCCGCTGCCGCCCGGTGACGAGCCGCTGCACTACCTGTTGCGCACGCCGTTTCGCTACCCGCCGCTGCGCTGGGGCTCG
CGTTTCGGCCGGCGCCATGAGCCGAGCCTGTTCTACGCCGCCTGCCGGCTGGAGACGGCGATGGCCGAGACCGCCTTCTA
TCGTTTCGTGCTGTGGTACGGCATGGTCGAGCCGCCGCCGAGCGGGCGCATCCTTTCCGAGCATTCGTCCTTCGAGGCGC
GCTACCAGGTGCAGCGCGGGGTGCGCCTGCAGCTACCGCCATTCGACGGCCATCGCGCGCTGCTGACCCATCGCAGTGAC
TATCGCGCCACCCACAGCCTGGGAAGCGCGATGCGCGAAGCGGGGGTGGAAGCGTTCGAGTATCCCTCGGCGCGCTGCCC
GCAGGGGGGCAACAACGTTGCCCTGTATGCGCCGACGGCGTTCAGCGAGAAGCGGCCGCGCAACCTGCAGCCGTGGCTAT
GCGAAACCACCGCAGGCTACGTGGCTTTCAAGAACGCCCAGGCGCCTGATACACCGCGCCTGTACGCCCTTGATCTGTAT
CTCGAGGATGGCGTGCTGCCGCAGCCACCCTGA
Antitoxin
Download Length: 124 a.a. Molecular weight: 13394.56 Da Isoelectric Point: 10.8344
>AT38430 WP_203791757.1 NZ_AP024354:1464415-1464786 [Pseudomonas alcaligenes]
MSALSKPGVDAGTVLLKALLNSREQLGLTQQELAAIVGVNRSAISRWSDSGGLRPESKTGELALLLIRAYRALFALFGGN
LQDMRHFLRTENRHLAGVPLQQMGQVQGLVRVVEYLDAIRGKV
MSALSKPGVDAGTVLLKALLNSREQLGLTQQELAAIVGVNRSAISRWSDSGGLRPESKTGELALLLIRAYRALFALFGGN
LQDMRHFLRTENRHLAGVPLQQMGQVQGLVRVVEYLDAIRGKV
Download Length: 372 bp
>AT38430 NZ_AP024354:1464415-1464786 [Pseudomonas alcaligenes]
ATGAGCGCACTCAGCAAGCCAGGTGTCGATGCCGGCACCGTCCTGCTCAAGGCCCTGCTCAACAGCCGTGAGCAGCTGGG
CCTGACCCAGCAGGAGCTGGCGGCGATAGTCGGCGTCAACCGTTCCGCCATCAGTCGCTGGAGCGACAGCGGCGGCCTGC
GTCCGGAGAGCAAGACCGGTGAGCTGGCCTTGCTGCTGATCCGCGCCTATCGCGCCCTGTTCGCCCTGTTCGGCGGCAAT
CTGCAGGACATGCGGCATTTCCTGCGCACCGAGAATCGCCATCTGGCCGGTGTGCCCTTGCAGCAGATGGGGCAGGTACA
GGGGCTGGTGCGGGTGGTCGAGTACCTGGACGCCATCCGCGGCAAGGTCTGA
ATGAGCGCACTCAGCAAGCCAGGTGTCGATGCCGGCACCGTCCTGCTCAAGGCCCTGCTCAACAGCCGTGAGCAGCTGGG
CCTGACCCAGCAGGAGCTGGCGGCGATAGTCGGCGTCAACCGTTCCGCCATCAGTCGCTGGAGCGACAGCGGCGGCCTGC
GTCCGGAGAGCAAGACCGGTGAGCTGGCCTTGCTGCTGATCCGCGCCTATCGCGCCCTGTTCGCCCTGTTCGGCGGCAAT
CTGCAGGACATGCGGCATTTCCTGCGCACCGAGAATCGCCATCTGGCCGGTGTGCCCTTGCAGCAGATGGGGCAGGTACA
GGGGCTGGTGCGGGTGGTCGAGTACCTGGACGCCATCCGCGGCAAGGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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