Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3084666..3085941 Replicon chromosome
Accession NZ_AP024342
Organism Pseudomonas sp. Eqa60

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KI242_RS14310 Protein ID WP_212806279.1
Coordinates 3085342..3085941 (+) Length 200 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KI242_RS14305 Protein ID WP_123725179.1
Coordinates 3084666..3085223 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI242_RS14275 (PEQA60_28400) 3079918..3080568 + 651 WP_103291076.1 DUF2239 family protein -
KI242_RS14280 (PEQA60_28410) 3080656..3081276 + 621 WP_011060979.1 LysE family translocator -
KI242_RS14285 (PEQA60_28420) 3081322..3081909 - 588 WP_011060980.1 AidA/PixA family protein -
KI242_RS14290 (PEQA60_28430) 3082321..3083508 + 1188 WP_161466914.1 PrpF domain-containing protein -
KI242_RS14295 (PEQA60_28440) 3083687..3084133 - 447 WP_228102409.1 hypothetical protein -
KI242_RS14300 (PEQA60_28450) 3084135..3084476 - 342 WP_212806278.1 low molecular weight protein tyrosine phosphatase family protein -
KI242_RS14305 (PEQA60_28460) 3084666..3085223 + 558 WP_123725179.1 helix-turn-helix transcriptional regulator Antitoxin
KI242_RS14310 (PEQA60_28470) 3085342..3085941 + 600 WP_212806279.1 HD domain-containing protein Toxin
KI242_RS14315 (PEQA60_28480) 3086156..3088336 + 2181 WP_212806280.1 catalase/peroxidase HPI -
KI242_RS14320 (PEQA60_28490) 3088464..3088892 - 429 WP_011060992.1 hypothetical protein -
KI242_RS14325 (PEQA60_28500) 3089127..3090041 + 915 WP_212806281.1 SGNH/GDSL hydrolase family protein -
KI242_RS14330 (PEQA60_28510) 3090389..3090652 + 264 WP_072442108.1 hypothetical protein -
KI242_RS14335 (PEQA60_28520) 3090655..3090843 + 189 WP_244868199.1 DUF6360 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(8-191)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 200 a.a.        Molecular weight: 22415.23 Da        Isoelectric Point: 5.8364

>T38403 WP_212806279.1 NZ_AP024342:3085342-3085941 [Pseudomonas sp. Eqa60]
MNSELLSGRLDFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGDLDLLRVLKLCIVHDLGEAIHGDIP
AVAQAAHPDKSQQERADLQLLARALDAPAREHLLELWDEYEGAASAEARAVKALDKLETLLQHTQGQNPAGFDYRFNLGY
GRRYTDASPLFQALRQQIDVDTQRRLDAQAQAAVQHRLR

Download         Length: 600 bp

>T38403 NZ_AP024342:3085342-3085941 [Pseudomonas sp. Eqa60]
ATGAACAGTGAACTTCTCAGCGGCCGTCTCGACTTTCTCCGTGAAGCGGAAAAACTCAAGGACGTGCTGCGCAGCGCCCA
CACCTCCAGCGGCCGCCAGGAAAGCACGGCCGAGCACAGCTGGCGCCTGTGCCTGATGGCGCTGCTGTTCGAAGACCAAC
TGGGGGACCTGGACCTGCTGCGGGTGCTGAAACTGTGCATCGTCCACGACCTGGGGGAGGCCATTCATGGCGACATCCCG
GCGGTGGCCCAGGCCGCCCACCCGGACAAGAGCCAGCAGGAGCGCGCGGACCTGCAACTGCTGGCCCGAGCCCTGGACGC
CCCGGCCCGCGAGCACCTGCTGGAGCTGTGGGACGAATACGAAGGCGCCGCCAGCGCCGAGGCGCGCGCGGTCAAGGCCC
TGGACAAGCTGGAAACCCTGCTGCAACACACCCAGGGCCAGAACCCGGCGGGTTTCGACTACCGCTTCAACCTCGGCTAC
GGCCGCCGCTACACCGACGCCAGCCCACTGTTCCAGGCCCTGCGCCAGCAGATCGACGTCGATACCCAGCGCCGCCTGGA
CGCCCAGGCTCAGGCCGCGGTTCAGCATCGGCTGCGCTAA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20397.32 Da        Isoelectric Point: 7.0307

>AT38403 WP_123725179.1 NZ_AP024342:3084666-3085223 [Pseudomonas sp. Eqa60]
MSVALFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGQQAMEPAERVRLEQLLAANLSAAADQALARLVND
SPRAVHLVCDLTHRLLACSATRAGQFGVPLSELLGQSLWGFCTEEITRKEAALDDLGWREVLAPPSLEFFSGHNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL

Download         Length: 558 bp

>AT38403 NZ_AP024342:3084666-3085223 [Pseudomonas sp. Eqa60]
ATGTCCGTAGCTCTGTTCACCTCCCCCCATCTGGGCCTGGCCCTCAGGCGCTGGCGCCTGTTGCACCGGGTCAAGCAGCA
GCACGCCGCCGAACTGTTCGGCGTGGCGCAGTCGAGCATTTCCCGTTGGGAAAACGGCCAGCAGGCCATGGAACCGGCCG
AGCGTGTGCGCCTGGAACAACTGCTGGCGGCCAACCTCAGCGCCGCCGCCGACCAGGCCCTGGCGCGGCTGGTGAACGAC
AGCCCGCGCGCCGTGCACCTGGTGTGCGACCTGACCCACCGCCTGCTGGCCTGTTCAGCGACCCGCGCCGGGCAGTTCGG
CGTGCCCCTGAGTGAGCTGCTGGGCCAGTCCCTGTGGGGCTTTTGCACCGAGGAAATCACCCGCAAGGAAGCCGCCCTGG
ATGACCTGGGCTGGCGTGAAGTGCTGGCGCCGCCGTCCCTGGAGTTCTTCAGCGGCCACAACGATTCGGCCATCGTGCCC
ATCGCCCCCAGCCAGTGCCGCTGGACCCGCCTCAACCTGTCCGACGGCAACGCCGTGCGGCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References