Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 102557..103200 Replicon plasmid pERA54
Accession NZ_AP024332
Organism Erwinia rhapontici strain MAFF 311154

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag KI233_RS24280 Protein ID WP_212816183.1
Coordinates 102784..103200 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag KI233_RS24275 Protein ID WP_212816182.1
Coordinates 102557..102787 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI233_RS24255 (ERHA54_49860) 98242..99552 - 1311 WP_212816181.1 PAS domain-containing methyl-accepting chemotaxis protein -
KI233_RS24260 (ERHA54_49870) 99758..100666 - 909 WP_133846718.1 EamA family transporter -
KI233_RS24265 (ERHA54_49880) 100782..101552 + 771 WP_167863535.1 helix-turn-helix transcriptional regulator -
KI233_RS24270 (ERHA54_49890) 101924..102070 - 147 WP_166653768.1 hypothetical protein -
KI233_RS24275 (ERHA54_49900) 102557..102787 + 231 WP_212816182.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
KI233_RS24280 (ERHA54_49910) 102784..103200 + 417 WP_212816183.1 type II toxin-antitoxin system VapC family toxin Toxin
KI233_RS24285 103241..104118 - 878 Protein_98 restriction endonuclease -
KI233_RS24290 (ERHA54_49940) 104493..104996 - 504 WP_212816184.1 GrpB family protein -
KI233_RS24295 (ERHA54_49950) 105627..106046 + 420 WP_212816185.1 VOC family protein -
KI233_RS24300 (ERHA54_49960) 106080..106427 - 348 WP_212816256.1 NIPSNAP family protein -
KI233_RS24305 (ERHA54_49970) 106787..107215 + 429 WP_212816257.1 GFA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..192843 192843


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-129)

Antitoxin

SpoVT-AbrB domain

(7-44)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15159.60 Da        Isoelectric Point: 7.2159

>T38386 WP_212816183.1 NZ_AP024332:102784-103200 [Erwinia rhapontici]
VNKMYMLDTCICSFIMREQPEAVLRRLEQAVLRGHRIVVSAITYSEMRFGATGPKASPRHVPLVDEFCARLDAVLPWDRA
AVDATTDIKVALRLVGTPIGPNDTAIAGHAMAAGAVLVTNNTREFERVPGLVLEDWSK

Download         Length: 417 bp

>T38386 NZ_AP024332:102784-103200 [Erwinia rhapontici]
GTGAACAAAATGTATATGCTCGACACCTGTATCTGCTCGTTCATCATGCGCGAGCAGCCGGAAGCGGTGCTGAGGCGCCT
GGAGCAGGCGGTGCTGCGCGGCCACCGTATCGTGGTCTCGGCCATTACTTACTCTGAAATGCGCTTCGGGGCCACCGGCC
CGAAGGCCTCGCCGCGTCACGTCCCGCTGGTCGACGAATTCTGCGCCCGCCTCGATGCCGTCCTTCCATGGGACCGGGCC
GCGGTGGACGCCACCACGGACATTAAAGTGGCGCTGCGCCTGGTCGGAACGCCGATCGGCCCGAACGACACGGCGATTGC
CGGACACGCCATGGCCGCCGGTGCCGTGCTGGTGACTAACAATACGCGGGAGTTTGAGCGGGTGCCGGGGTTAGTACTTG
AAGACTGGTCGAAGTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8674.73 Da        Isoelectric Point: 4.4857

>AT38386 WP_212816182.1 NZ_AP024332:102557-102787 [Erwinia rhapontici]
MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDSIILRPVRPTWGSFADHEKADPDFMAERGDVVVDEGRFDL

Download         Length: 231 bp

>AT38386 NZ_AP024332:102557-102787 [Erwinia rhapontici]
ATGAGAACCGTATCCATTTTTAAAAATGGCAACAACCGCGCCATCCGTCTGCCCCGCGATCTGGATTTTGAGGGTGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATCCTGCGCCCAGTCCGGCCGACCTGGGGCTCGTTCGCTGACCACG
AAAAGGCCGATCCGGACTTCATGGCGGAGCGCGGGGACGTTGTCGTCGACGAAGGACGATTTGACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References