Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4143662..4144322 Replicon chromosome
Accession NZ_AP024331
Organism Erwinia rhapontici strain MAFF 311154

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag KI233_RS19075 Protein ID WP_159337897.1
Coordinates 4143662..4144075 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag KI233_RS19080 Protein ID WP_133846122.1
Coordinates 4144056..4144322 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI233_RS19055 (ERHA54_39480) 4139490..4140008 + 519 WP_133846139.1 flavodoxin FldB -
KI233_RS19060 (ERHA54_39490) 4140105..4141466 - 1362 WP_133846118.1 cell envelope integrity protein CreD -
KI233_RS19065 (ERHA54_39500) 4141556..4142974 - 1419 WP_133846119.1 two-component system sensor histidine kinase CreC -
KI233_RS19070 (ERHA54_39510) 4142974..4143669 - 696 WP_133846120.1 two-component system response regulator CreB -
KI233_RS19075 (ERHA54_39520) 4143662..4144075 - 414 WP_159337897.1 protein YgfX Toxin
KI233_RS19080 (ERHA54_39530) 4144056..4144322 - 267 WP_133846122.1 FAD assembly factor SdhE Antitoxin
KI233_RS19085 (ERHA54_39540) 4144549..4145535 + 987 WP_212813250.1 tRNA-modifying protein YgfZ -
KI233_RS19090 (ERHA54_39550) 4145547..4146200 - 654 WP_133846124.1 hemolysin III family protein -
KI233_RS19095 (ERHA54_39560) 4146413..4147021 + 609 WP_212813252.1 HD domain-containing protein -
KI233_RS19100 (ERHA54_39570) 4147092..4147814 - 723 WP_133846126.1 class I SAM-dependent methyltransferase -
KI233_RS19105 (ERHA54_39580) 4147860..4148615 + 756 WP_159337894.1 hydroxyacylglutathione hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-130)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16244.17 Da        Isoelectric Point: 11.8917

>T38384 WP_159337897.1 NZ_AP024331:c4144075-4143662 [Erwinia rhapontici]
VVRWRCNLRASRRAQTLSLVLHGTLILALLLAPWPDSVSLPRILLLLLVLLECQCSRHRIRHCRGEITLHKGRVIVWAQC
QWRMTSRPWLTQRAIRLTLQNTAGRRERLWLFADGMDSSEWRLLRQHLLNEKEPRDE

Download         Length: 414 bp

>T38384 NZ_AP024331:c4144075-4143662 [Erwinia rhapontici]
GTGGTCCGGTGGCGATGTAATCTGCGGGCCTCCCGGCGCGCACAAACGTTATCGCTGGTACTGCATGGCACGTTGATCCT
GGCGCTGCTGCTGGCACCCTGGCCGGACAGCGTCTCATTGCCACGCATCCTGTTACTGCTGCTGGTTCTTCTGGAGTGCC
AGTGCAGTCGACATCGTATCCGGCATTGTCGGGGGGAGATCACCCTGCACAAGGGGCGTGTGATAGTCTGGGCGCAGTGC
CAGTGGCGCATGACCTCCCGCCCGTGGCTGACGCAACGGGCGATTCGGCTGACATTACAGAACACGGCAGGCCGTCGCGA
GCGGTTATGGCTATTTGCCGATGGCATGGACAGCAGCGAATGGCGGCTTCTGCGCCAACACCTGCTGAATGAAAAGGAAC
CGCGGGATGAGTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10414.85 Da        Isoelectric Point: 4.6290

>AT38384 WP_133846122.1 NZ_AP024331:c4144322-4144056 [Erwinia rhapontici]
MDISNKSRIHWACRRGMRELDISIMPFFQYEFDSLTDEDKQLFVRLLESDDPDLFNWLMNHGEPADAELQRMVALIQDRN
RARGPVAM

Download         Length: 267 bp

>AT38384 NZ_AP024331:c4144322-4144056 [Erwinia rhapontici]
ATGGATATTTCAAATAAATCACGTATTCACTGGGCATGCCGTCGTGGCATGCGCGAACTCGATATCTCCATCATGCCGTT
TTTCCAGTATGAGTTTGATTCACTGACCGATGAAGACAAACAGCTCTTCGTACGTCTGCTGGAGAGTGATGACCCCGATT
TGTTTAACTGGCTGATGAATCACGGTGAACCCGCTGATGCTGAGCTGCAACGGATGGTGGCATTAATTCAGGACAGAAAC
CGAGCACGTGGTCCGGTGGCGATGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References