Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 3156874..3157400 Replicon chromosome
Accession NZ_AP024331
Organism Erwinia rhapontici strain MAFF 311154

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag KI233_RS14680 Protein ID WP_212815477.1
Coordinates 3157095..3157400 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag KI233_RS14675 Protein ID WP_133841674.1
Coordinates 3156874..3157092 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI233_RS14650 (ERHA54_30420) 3152526..3153383 + 858 WP_212815476.1 iron/manganese ABC transporter permease subunit SitC -
KI233_RS14655 (ERHA54_30430) 3153380..3154216 + 837 WP_167863850.1 metal ABC transporter permease -
KI233_RS14660 (ERHA54_30440) 3154262..3155698 - 1437 WP_200643307.1 glycoside hydrolase family 1 protein -
KI233_RS14670 (ERHA54_30470) 3156485..3156736 - 252 WP_159336428.1 hypothetical protein -
KI233_RS14675 (ERHA54_30480) 3156874..3157092 + 219 WP_133841674.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
KI233_RS14680 (ERHA54_30490) 3157095..3157400 + 306 WP_212815477.1 type II toxin-antitoxin system toxin CcdB Toxin
KI233_RS14685 (ERHA54_30500) 3157557..3157994 - 438 WP_212812957.1 hypothetical protein -
KI233_RS14690 (ERHA54_30510) 3158045..3159433 - 1389 WP_167863719.1 ATP-binding protein -
KI233_RS14695 (ERHA54_30520) 3159433..3160110 - 678 WP_167863718.1 response regulator -
KI233_RS14700 (ERHA54_30530) 3160315..3161151 + 837 WP_212815478.1 MipA/OmpV family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11656.61 Da        Isoelectric Point: 6.8688

>T38383 WP_212815477.1 NZ_AP024331:3157095-3157400 [Erwinia rhapontici]
MQFIVYQYKRTSHYKIFVDVQSDIVDTPGRRMVIPLIESHHLSEKVNKTLFPLILIEGKNHRLMTTELSSVPVEVIGDAV
VDITRCQDDIKNAINLMFWGV

Download         Length: 306 bp

>T38383 NZ_AP024331:3157095-3157400 [Erwinia rhapontici]
ATGCAATTTATTGTTTATCAATATAAACGCACCAGCCATTACAAAATTTTTGTCGATGTGCAAAGTGATATTGTCGATAC
CCCTGGGCGACGCATGGTTATCCCGCTCATTGAATCGCACCATCTTTCTGAGAAAGTGAATAAAACCTTGTTCCCGCTGA
TCCTCATCGAGGGAAAAAATCACCGATTGATGACCACGGAACTTTCTAGTGTCCCTGTCGAGGTTATCGGTGATGCAGTA
GTGGATATCACCCGGTGTCAGGATGATATCAAAAATGCCATCAACCTCATGTTTTGGGGTGTTTGA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8149.12 Da        Isoelectric Point: 5.8316

>AT38383 WP_133841674.1 NZ_AP024331:3156874-3157092 [Erwinia rhapontici]
MKHRVSVTVDKENYLVLNAAGVNISGLVNDVIGKEARRIKAEEWKDQNREGMEEVASFIAKNGSFADENRNW

Download         Length: 219 bp

>AT38383 NZ_AP024331:3156874-3157092 [Erwinia rhapontici]
ATGAAACACAGAGTCAGCGTGACTGTAGACAAAGAGAACTATCTGGTTCTGAATGCTGCGGGCGTCAATATTTCTGGTCT
GGTGAATGATGTCATCGGCAAGGAAGCTCGTCGTATAAAGGCAGAAGAGTGGAAAGACCAGAACCGTGAAGGGATGGAGG
AAGTCGCCAGCTTTATCGCAAAGAATGGCTCTTTCGCCGATGAAAACAGGAACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References