Detailed information of TA system TA038377

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-MqsA
• Location: 851735..852440
• Replicon: chromosome
• Accession: NZ_AP024331
• Organism: Erwinia rhapontici strain MAFF 311154

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: KI233_RS03940
• Protein ID: WP_242462129.1
• Coordinates: 852048..852440 (-)
• Length: 131 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: KI233_RS03935
• Protein ID: WP_238337068.1
• Coordinates: 851735..852061 (-)
• Length: 109 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KI233_RS03900 (ERHA54_07950)	847697..848482	+	786	WP_133843655.1	DeoR/GlpR family DNA-binding transcription regulator	-
KI233_RS03905 (ERHA54_07960)	848499..848771	-	273	WP_133843653.1	type II toxin-antitoxin system RelE/ParE family toxin	-
KI233_RS03910 (ERHA54_07970)	848774..849208	-	435	WP_212813718.1	hypothetical protein	-
KI233_RS03915 (ERHA54_07980)	849290..849757	-	468	WP_133843649.1	Lrp/AsnC family transcriptional regulator	-
KI233_RS03920 (ERHA54_07990)	849903..850325	+	423	WP_212813720.1	DUF2000 domain-containing protein	-
KI233_RS03925 (ERHA54_08000)	850334..850786	+	453	WP_133843645.1	acyltransferase	-
KI233_RS03930 (ERHA54_08010)	851074..851646	+	573	WP_212813722.1	MepB family protein	-
KI233_RS03935 (ERHA54_08020)	851735..852061	-	327	WP_238337068.1	helix-turn-helix domain-containing protein	Antitoxin
KI233_RS03940 (ERHA54_08030)	852048..852440	-	393	WP_242462129.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
KI233_RS03945 (ERHA54_08040)	852973..854211	+	1239	WP_133843643.1	transporter substrate-binding protein	-
KI233_RS03950 (ERHA54_08050)	854221..855090	+	870	WP_133843641.1	branched-chain amino acid ABC transporter permease	-
KI233_RS03955 (ERHA54_08060)	855090..856112	+	1023	WP_167863870.1	branched-chain amino acid ABC transporter permease	-
KI233_RS03960 (ERHA54_08070)	856109..856840	+	732	WP_192933189.1	ATP-binding cassette domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (3-124)

Antitoxin

• Cro/C1-type helix-turn-helix domain (49-95)

Sequences

Toxin

Protein

• Length: 131 a.a.
• Molecular weight: 14650.67 Da
• Isoelectric Point: 7.8480

>T38377 WP_242462129.1 NZ_AP024331:c852440-852048 [Erwinia rhapontici]
VGIYVTNLFERSLKKQNIPDTTLCKIAQEIVSGLFDADLGGNVYKKRIPLQRGKSGGSRSIVAFRLGENLFFIDGWIKSD
VSKRGQKEIPDDDLETYRDIAHDFLSMSAQTINKAIETGRLREVHCYEPS

Nucleotide

• Length: 393 bp

>T38377 NZ_AP024331:c852440-852048 [Erwinia rhapontici]
GTGGGTATTTATGTGACCAACCTTTTCGAAAGAAGCCTTAAGAAGCAAAATATCCCAGACACAACACTGTGCAAAATCGC
TCAGGAAATTGTCAGCGGACTTTTCGATGCAGATTTAGGCGGAAATGTTTACAAAAAGCGCATCCCTTTACAGCGAGGCA
AAAGCGGAGGGTCGCGCTCAATTGTTGCCTTCAGATTGGGCGAAAACCTATTTTTCATTGATGGCTGGATTAAAAGCGAT
GTCAGCAAACGCGGACAGAAAGAAATTCCAGATGATGATTTGGAAACCTATCGCGATATTGCTCACGATTTTCTCAGCAT
GTCAGCTCAGACTATTAATAAGGCAATAGAGACAGGCAGATTAAGAGAGGTACATTGTTATGAGCCGTCTTAA

Antitoxin

Protein

• Length: 109 a.a.
• Molecular weight: 12259.30 Da
• Isoelectric Point: 10.5319

>AT38377 WP_238337068.1 NZ_AP024331:c852061-851735 [Erwinia rhapontici]
MSRLKQLQEMAHSFNEIGAVSDETVKRLDARIRAQEIREKLPKIMVMEGKDIRAMRDRLGISQAGLAYTMNMTVASISKW
ERGEKKPNGAALRLLNTLDRKGIEVFAE

Nucleotide

• Length: 327 bp

>AT38377 NZ_AP024331:c852061-851735 [Erwinia rhapontici]
ATGAGCCGTCTTAAACAACTACAGGAAATGGCGCACAGTTTTAATGAAATAGGTGCCGTTTCAGATGAGACAGTGAAACG
CCTGGATGCTCGCATCAGAGCGCAGGAAATTCGCGAAAAGTTGCCAAAAATCATGGTAATGGAAGGCAAAGATATCCGGG
CGATGCGTGACCGTTTGGGGATCAGCCAGGCCGGACTTGCCTATACGATGAATATGACAGTAGCCAGCATCTCAAAATGG
GAACGTGGAGAGAAAAAGCCAAATGGTGCCGCACTTCGCCTGTTAAACACCCTTGATCGTAAAGGGATTGAGGTTTTTGC
GGAGTAA