Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | TsaAT/- |
Location | 809401..809877 | Replicon | chromosome |
Accession | NZ_AP024318 | ||
Organism | Staphylococcus aureus strain S36 |
Toxin (Protein)
Gene name | TsaT | Uniprot ID | T1Y7S2 |
Locus tag | K5606_RS03775 | Protein ID | WP_000052076.1 |
Coordinates | 809401..809589 (-) | Length | 63 a.a. |
Antitoxin (Protein)
Gene name | TsaA | Uniprot ID | T1Y6P8 |
Locus tag | K5606_RS03780 | Protein ID | WP_001059690.1 |
Coordinates | 809617..809877 (-) | Length | 87 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
K5606_RS03745 (805429) | 805429..805911 | + | 483 | WP_000824489.1 | hypothetical protein | - |
K5606_RS03750 (806252) | 806252..806938 | + | 687 | WP_001574556.1 | thermonuclease family protein | - |
K5606_RS03755 (807295) | 807295..807495 | + | 201 | WP_001059082.1 | cold-shock protein | - |
K5606_RS03760 (807992) | 807992..808210 | - | 219 | WP_000005881.1 | hypothetical protein | - |
K5606_RS03765 (808271) | 808271..808555 | - | 285 | WP_001004403.1 | hypothetical protein | - |
K5606_RS03770 (808643) | 808643..809212 | - | 570 | WP_001106655.1 | lipoprotein N-acylation protein LnsA | - |
K5606_RS03775 (809401) | 809401..809589 | - | 189 | WP_000052076.1 | hypothetical protein | Toxin |
K5606_RS03780 (809617) | 809617..809877 | - | 261 | WP_001059690.1 | hypothetical protein | Antitoxin |
K5606_RS03785 (810219) | 810219..810422 | + | 204 | WP_000145163.1 | sterile alpha motif-like domain-containing protein | - |
K5606_RS03790 (810419) | 810419..810655 | - | 237 | WP_000368687.1 | hypothetical protein | - |
K5606_RS03795 (810880) | 810880..811461 | + | 582 | WP_001140696.1 | histidine phosphatase family protein | - |
K5606_RS03800 (811534) | 811534..812151 | - | 618 | WP_000255562.1 | LysE/ArgO family amino acid transporter | - |
K5606_RS03805 (812300) | 812300..812794 | - | 495 | WP_000569881.1 | GNAT family N-acetyltransferase | - |
K5606_RS03810 (813193) | 813193..813615 | - | 423 | WP_000974452.1 | organic hydroperoxide resistance protein | - |
K5606_RS03815 (813763) | 813763..814479 | + | 717 | WP_000150026.1 | type I 3-dehydroquinate dehydratase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 63 a.a. Molecular weight: 7142.82 Da Isoelectric Point: 9.9971
>T38356 WP_000052076.1 NZ_AP024318:c809589-809401 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL
Download Length: 189 bp
>T38356 NZ_AP024318:c809589-809401 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA
Antitoxin
Download Length: 87 a.a. Molecular weight: 9940.09 Da Isoelectric Point: 4.0624
>AT38356 WP_001059690.1 NZ_AP024318:c809877-809617 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG
Download Length: 261 bp
>AT38356 NZ_AP024318:c809877-809617 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATAGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATAGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0E0VP18 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0E0VN56 |