Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4631093..4631646 Replicon chromosome
Accession NZ_AP024269
Organism Kaistia sp. 32K

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K32_RS21345 Protein ID WP_201401438.1
Coordinates 4631353..4631646 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K32_RS21340 Protein ID WP_201401437.1
Coordinates 4631093..4631365 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K32_RS21320 4626303..4628051 - 1749 WP_201401435.1 heparinase II/III family protein -
K32_RS21325 4628283..4629560 - 1278 WP_201404602.1 methyltransferase domain-containing protein -
K32_RS21330 4629644..4630657 - 1014 WP_201401436.1 zinc metalloprotease HtpX -
K32_RS21335 4630835..4631029 + 195 WP_201404603.1 DUF1674 domain-containing protein -
K32_RS21340 4631093..4631365 + 273 WP_201401437.1 CopG family transcriptional regulator Antitoxin
K32_RS21345 4631353..4631646 + 294 WP_201401438.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K32_RS21350 4631668..4633608 - 1941 WP_201401439.1 acetate--CoA ligase -
K32_RS21355 4633698..4634360 - 663 WP_201401440.1 50S ribosomal protein L11 methyltransferase -
K32_RS21360 4634368..4634796 - 429 WP_201401441.1 EVE domain-containing protein -
K32_RS21365 4634842..4635120 - 279 WP_201401442.1 YciI family protein -
K32_RS21370 4635327..4636226 - 900 WP_201401443.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10943.67 Da        Isoelectric Point: 9.7651

>T38275 WP_201401438.1 NZ_AP024269:4631353-4631646 [Kaistia sp. 32K]
MPQIILTAGALAGIERCRSHLSARDPEAARRAASAIRERLQKLTLSPEIGRRVAEAPELRELVIPFGRLGYVALYHHDME
SDRLLILAFRHQREAGY

Download         Length: 294 bp

>T38275 NZ_AP024269:4631353-4631646 [Kaistia sp. 32K]
TTGCCACAAATAATCCTGACAGCCGGCGCGCTTGCCGGCATCGAGCGCTGCCGCAGCCACCTTTCTGCGCGCGATCCCGA
AGCAGCGCGCCGAGCCGCATCGGCAATCCGGGAACGACTGCAGAAACTGACCTTGTCGCCCGAAATCGGCCGCCGCGTCG
CCGAGGCGCCGGAACTGCGCGAGCTCGTGATCCCGTTTGGCAGGCTCGGCTATGTCGCGCTCTACCATCACGACATGGAA
TCGGACCGCCTGCTGATCCTTGCCTTTCGCCATCAGCGGGAGGCCGGCTACTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9943.12 Da        Isoelectric Point: 4.1955

>AT38275 WP_201401437.1 NZ_AP024269:4631093-4631365 [Kaistia sp. 32K]
MTLSVKLDPDAEARLKALAETRRLDPDVMLHEAIVEYLDREEARQAFKAEALASLSAFGEDGLHLTLDETEAWLDGWGTD
ADAPPPPCHK

Download         Length: 273 bp

>AT38275 NZ_AP024269:4631093-4631365 [Kaistia sp. 32K]
ATGACGTTGTCAGTCAAGCTGGATCCTGATGCCGAGGCGCGCCTGAAGGCGCTGGCCGAGACGCGTCGTCTCGATCCGGA
TGTCATGCTGCACGAGGCGATCGTGGAATATCTCGATCGCGAGGAGGCGCGTCAGGCCTTCAAGGCGGAGGCGTTGGCCT
CGCTCAGCGCCTTTGGCGAGGACGGGTTGCATCTGACCCTCGACGAGACCGAGGCCTGGCTCGACGGCTGGGGCACGGAT
GCGGATGCGCCTCCGCCGCCTTGCCACAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References