38179

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 4081334..4082028 Replicon chromosome
Accession NZ_AP024238
Organism Rhodoferax sp. MIZ03

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag LDN84_RS18780 Protein ID WP_223913129.1
Coordinates 4081666..4082028 (-) Length 121 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag LDN84_RS18775 Protein ID WP_223904946.1
Coordinates 4081334..4081669 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDN84_RS18755 (MIZ03_3959) 4076944..4077225 - 282 WP_223904942.1 hypothetical protein -
LDN84_RS18760 (MIZ03_3962) 4078686..4079402 - 717 WP_223904943.1 inovirus-type Gp2 protein -
LDN84_RS18765 (MIZ03_3963) 4080605..4080853 + 249 WP_223904944.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
LDN84_RS18770 (MIZ03_3964) 4080850..4081236 + 387 WP_223904945.1 type II toxin-antitoxin system VapC family toxin -
LDN84_RS18775 (MIZ03_3965) 4081334..4081669 - 336 WP_223904946.1 helix-turn-helix transcriptional regulator Antitoxin
LDN84_RS18780 (MIZ03_3966) 4081666..4082028 - 363 WP_223913129.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LDN84_RS18785 (MIZ03_3968) 4082565..4083989 - 1425 WP_223904947.1 tyrosine-type recombinase/integrase -
LDN84_RS18795 (MIZ03_3971) 4084479..4084943 + 465 WP_223904948.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-109)

Antitoxin

Cro/C1-type helix-turn-helix domain

(40-93)


Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13217.37 Da        Isoelectric Point: 9.8505

>T38179 WP_223913129.1 NZ_AP024238:c4082028-4081666 [Rhodoferax sp. MIZ03]
MLRNEKSLEWIGSSHKDLMALPADVRRLFGFALSLAQAGDKHDAAKVLKGFGGAGVLEVVEDDAGGTYRAVYTVKFAEAV
FVLHCFQKKSKRGIATPKEDMDIIHARLKIAEAFAKELRK

Download         Length: 363 bp

>T38179 NZ_AP024238:c4082028-4081666 [Rhodoferax sp. MIZ03]
ATGCTCAGAAACGAAAAATCCCTTGAATGGATAGGTAGCAGCCATAAAGACTTGATGGCCTTGCCTGCGGACGTAAGGCG
ACTTTTTGGCTTCGCTTTGTCGTTGGCACAGGCTGGCGATAAGCACGACGCGGCCAAAGTGCTCAAGGGTTTTGGCGGTG
CTGGTGTGCTTGAGGTGGTGGAAGACGATGCTGGCGGCACCTACCGTGCCGTATATACCGTCAAATTTGCCGAGGCAGTG
TTTGTCCTTCACTGCTTCCAGAAGAAAAGCAAGCGCGGCATCGCCACGCCGAAAGAAGATATGGACATCATCCACGCAAG
GCTGAAAATAGCTGAAGCGTTTGCAAAGGAGTTGCGGAAATGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12228.38 Da        Isoelectric Point: 9.7147

>AT38179 WP_223904946.1 NZ_AP024238:c4081669-4081334 [Rhodoferax sp. MIZ03]
MKIRLIDGIEVQRGSDNVFADLGLPDADKLKIKTGLVIEIRKAMSNGGLTQQEAAKRMGITQPKVSDMMRGDFTNLSERK
LMDCLTRLGYDIEIKVRPAKAEVGHLMLAAA

Download         Length: 336 bp

>AT38179 NZ_AP024238:c4081669-4081334 [Rhodoferax sp. MIZ03]
ATGAAAATCCGACTGATTGATGGCATTGAAGTGCAACGGGGTTCTGATAACGTGTTTGCCGACCTTGGTCTGCCTGATGC
TGACAAGCTCAAGATCAAAACAGGTTTGGTCATAGAGATCAGGAAAGCCATGAGCAACGGGGGCTTGACACAACAAGAAG
CAGCCAAACGCATGGGCATCACGCAACCCAAAGTCTCTGACATGATGCGCGGCGACTTTACAAACCTGTCTGAGCGCAAA
TTAATGGATTGCCTTACCCGACTTGGCTACGACATTGAGATCAAAGTCCGACCTGCCAAGGCAGAAGTTGGACATCTGAT
GCTGGCTGCGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References