Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 1982261..1982851 Replicon chromosome
Accession NZ_AP024238
Organism Rhodoferax sp. MIZ03

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LDN84_RS09175 Protein ID WP_223911499.1
Coordinates 1982261..1982560 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LDN84_RS09180 Protein ID WP_223911502.1
Coordinates 1982564..1982851 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDN84_RS09160 (MIZ03_1942) 1978802..1980244 + 1443 WP_223911489.1 exodeoxyribonuclease I -
LDN84_RS09165 (MIZ03_1944) 1980866..1981498 + 633 WP_223911493.1 HEPN domain-containing protein -
LDN84_RS09170 (MIZ03_1945) 1981593..1981883 + 291 WP_223911496.1 hypothetical protein -
LDN84_RS09175 (MIZ03_1947) 1982261..1982560 + 300 WP_223911499.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LDN84_RS09180 (MIZ03_1948) 1982564..1982851 + 288 WP_223911502.1 putative addiction module antidote protein Antitoxin
LDN84_RS09185 (MIZ03_1949) 1982967..1983887 - 921 WP_223911506.1 AEC family transporter -
LDN84_RS09190 (MIZ03_1950) 1983907..1984836 + 930 WP_223911509.1 site-specific tyrosine recombinase XerD -
LDN84_RS09195 (MIZ03_1951) 1984853..1986109 - 1257 WP_223911512.1 HDOD domain-containing protein -
LDN84_RS09200 (MIZ03_1952) 1986109..1986975 - 867 WP_223911515.1 ferritin-like domain-containing protein -
LDN84_RS09205 (MIZ03_1953) 1987017..1987541 + 525 WP_223911518.1 gamma carbonic anhydrase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(5-92)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11341.02 Da        Isoelectric Point: 9.5963

>T38177 WP_223911499.1 NZ_AP024238:1982261-1982560 [Rhodoferax sp. MIZ03]
MITFHRSDEFDTWLAALKDKIGRARIALRIRSAEHGNFGDCEPVGEGVSEMRIHFGPGYRVYFTRRGEVLYLLLLGGDKS
SQKRDIKRAIEMARALDKE

Download         Length: 300 bp

>T38177 NZ_AP024238:1982261-1982560 [Rhodoferax sp. MIZ03]
ATGATCACCTTTCACCGCTCAGACGAATTTGACACTTGGCTTGCGGCATTGAAGGACAAGATAGGCCGTGCTCGTATCGC
TCTTCGCATCCGCTCTGCCGAGCATGGCAACTTCGGAGACTGTGAACCCGTCGGCGAGGGAGTTTCTGAAATGCGTATTC
ATTTCGGTCCTGGCTATCGTGTTTATTTCACCCGTCGTGGTGAGGTGCTCTATCTGCTTCTGTTGGGTGGCGACAAGTCT
TCGCAGAAGCGCGACATCAAACGCGCCATTGAGATGGCGCGGGCTTTGGACAAGGAGTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10299.72 Da        Isoelectric Point: 5.0745

>AT38177 WP_223911502.1 NZ_AP024238:1982564-1982851 [Rhodoferax sp. MIZ03]
MAKFSPFDAADYLDDEETISEYITAALEDSNPDVFLTAVRDVARARGMAQLAKDAGLGRESLYKALTPGAKPRYDTMLKL
LHALGVKLSASPIHS

Download         Length: 288 bp

>AT38177 NZ_AP024238:1982564-1982851 [Rhodoferax sp. MIZ03]
ATGGCCAAATTTTCCCCATTCGATGCAGCCGACTATCTCGACGATGAAGAAACCATCTCGGAATACATCACCGCTGCGCT
GGAAGATTCCAATCCTGATGTATTTTTAACCGCCGTGCGTGATGTGGCTCGCGCCCGTGGCATGGCACAACTCGCTAAAG
ATGCCGGTCTTGGGCGTGAAAGCCTCTACAAGGCACTTACGCCCGGCGCAAAGCCTCGCTATGACACGATGCTCAAGTTG
CTTCATGCTCTCGGCGTAAAGCTCTCCGCTTCCCCCATTCATTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References