Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 1728947..1729521 Replicon chromosome
Accession NZ_AP024238
Organism Rhodoferax sp. MIZ03

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LDN84_RS07980 Protein ID WP_223910858.1
Coordinates 1728947..1729243 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LDN84_RS07985 Protein ID WP_223910861.1
Coordinates 1729231..1729521 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDN84_RS07965 (MIZ03_1697) 1724527..1725294 - 768 WP_223910850.1 transporter substrate-binding domain-containing protein -
LDN84_RS07970 (MIZ03_1698) 1725501..1728125 - 2625 WP_223910853.1 ABC transporter permease -
LDN84_RS07975 (MIZ03_1699) 1728137..1728910 - 774 WP_223910856.1 carbon-nitrogen hydrolase family protein -
LDN84_RS07980 (MIZ03_1700) 1728947..1729243 - 297 WP_223910858.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LDN84_RS07985 (MIZ03_1701) 1729231..1729521 - 291 WP_223910861.1 CopG family ribbon-helix-helix protein Antitoxin
LDN84_RS07990 (MIZ03_1702) 1729737..1730576 + 840 WP_223910864.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -
LDN84_RS07995 (MIZ03_1703) 1730581..1732224 + 1644 WP_223910867.1 diguanylate cyclase -
LDN84_RS08000 (MIZ03_1705) 1732440..1733231 - 792 WP_223910871.1 DUF4349 domain-containing protein -
LDN84_RS08005 (MIZ03_1706) 1733348..1733776 - 429 WP_223910873.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-46)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11273.06 Da        Isoelectric Point: 7.3160

>T38176 WP_223910858.1 NZ_AP024238:c1729243-1728947 [Rhodoferax sp. MIZ03]
MPRLIWSPPALQDVQRLYRFLAVQSSDAAKKAVKTIREGVKVLALQPGMGRPTEEMSPEFREWLIDFGHSGYVILYHFED
DAVMILAVRHQKEVGYKD

Download         Length: 297 bp

>T38176 NZ_AP024238:c1729243-1728947 [Rhodoferax sp. MIZ03]
ATGCCACGTCTGATCTGGTCACCGCCTGCGTTGCAGGATGTGCAGCGCCTCTATCGCTTCCTGGCCGTTCAAAGTTCAGA
TGCTGCAAAAAAAGCCGTCAAAACGATCCGCGAAGGTGTCAAAGTTCTGGCACTGCAGCCAGGCATGGGGCGACCTACCG
AAGAGATGTCCCCTGAGTTTCGTGAGTGGCTGATTGACTTTGGTCACAGTGGTTACGTCATCCTGTATCACTTTGAGGAT
GATGCCGTCATGATTCTGGCTGTACGCCACCAAAAGGAAGTGGGCTACAAGGACTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11211.51 Da        Isoelectric Point: 6.2280

>AT38176 WP_223910861.1 NZ_AP024238:c1729521-1729231 [Rhodoferax sp. MIZ03]
MTTTATRPMTIKIDLDTRERVQRLADARQRTSHWLMREAISQYVEREEKRQAYRQDGINAWKAYQANGLHVTSQEADAWL
DKLEAGQDVEPPECHV

Download         Length: 291 bp

>AT38176 NZ_AP024238:c1729521-1729231 [Rhodoferax sp. MIZ03]
ATGACCACCACAGCCACTCGCCCCATGACCATCAAGATTGATCTGGACACCCGCGAGCGGGTGCAGCGTCTGGCTGATGC
GCGTCAGCGCACCTCTCACTGGCTGATGCGCGAAGCCATCAGCCAATATGTGGAACGCGAAGAAAAGCGCCAGGCTTATC
GGCAAGACGGCATCAACGCATGGAAAGCCTACCAAGCTAACGGCTTGCATGTCACCAGCCAAGAAGCCGATGCCTGGCTG
GACAAGCTGGAAGCAGGGCAGGACGTGGAACCGCCTGAATGCCACGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References