38175

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1176430..1178183 Replicon chromosome
Accession NZ_AP024238
Organism Rhodoferax sp. MIZ03

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag LDN84_RS05495 Protein ID WP_223909555.1
Coordinates 1177539..1178183 (-) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag LDN84_RS05490 Protein ID WP_223909552.1
Coordinates 1176430..1177539 (-) Length 370 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDN84_RS05485 (MIZ03_1172) 1174985..1176214 + 1230 WP_223909549.1 alpha/beta fold hydrolase -
LDN84_RS05490 (MIZ03_1174) 1176430..1177539 - 1110 WP_223909552.1 macro domain-containing protein Antitoxin
LDN84_RS05495 (MIZ03_1175) 1177539..1178183 - 645 WP_223909555.1 DUF4433 domain-containing protein Toxin
LDN84_RS05500 (MIZ03_1176) 1178180..1178752 - 573 WP_223909559.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
LDN84_RS05505 (MIZ03_1178) 1178991..1181219 - 2229 WP_223909561.1 malate synthase G -
LDN84_RS05510 (MIZ03_1179) 1181244..1182005 - 762 WP_223909564.1 haloacid dehalogenase type II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-214)

Antitoxin

Macro domain

(18-128)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24582.07 Da        Isoelectric Point: 7.6313

>T38175 WP_223909555.1 NZ_AP024238:c1178183-1177539 [Rhodoferax sp. MIZ03]
MIYKNLNPEKALIWRIIHRDNLPWVLAHGLHCGNGVQQAPNWVHIGNSELIDKRAHHTVPLPPGGVLNDYVPFYFTPFSV
MMRNIRSGRGGVQQRDNDEIVILVSSLHHVAQQGLPFLFTDMHAYYRWATYYNDLAHLDKVDWALLQARDFKRDENDPAK
FERYQAEALIHRHCPVSGLIGMVCHSEEGKMQAQTQVAAQGLNLPVHARPGWYF

Download         Length: 645 bp

>T38175 NZ_AP024238:c1178183-1177539 [Rhodoferax sp. MIZ03]
ATGATCTACAAAAACCTCAATCCCGAGAAAGCGCTGATCTGGCGCATCATCCATCGCGACAACCTGCCATGGGTGCTGGC
GCACGGCCTGCACTGCGGCAACGGTGTTCAACAAGCGCCGAACTGGGTACACATTGGTAATTCGGAGTTGATTGACAAGC
GGGCTCACCATACCGTGCCGCTGCCACCAGGTGGCGTGCTGAACGACTATGTGCCGTTTTACTTCACGCCCTTCTCGGTG
ATGATGCGCAACATACGCTCTGGGCGTGGTGGTGTGCAACAGCGGGACAACGATGAAATTGTGATTCTGGTATCGAGCCT
GCATCATGTGGCGCAGCAAGGGCTGCCGTTTTTGTTCACCGACATGCACGCCTACTACCGCTGGGCCACTTACTACAACG
ATCTGGCTCACCTGGACAAAGTGGATTGGGCGCTACTGCAAGCGAGGGACTTCAAACGTGACGAAAACGACCCCGCCAAA
TTCGAGCGCTACCAAGCCGAAGCGCTGATCCATCGGCACTGCCCGGTGTCCGGGTTGATTGGGATGGTTTGCCATTCAGA
AGAAGGCAAAATGCAGGCTCAAACGCAAGTTGCGGCTCAAGGGCTGAATTTGCCGGTTCATGCACGTCCGGGGTGGTATT
TCTGA

Antitoxin


Download         Length: 370 a.a.        Molecular weight: 41636.01 Da        Isoelectric Point: 6.7503

>AT38175 WP_223909552.1 NZ_AP024238:c1177539-1176430 [Rhodoferax sp. MIZ03]
MLNFTTGNLLEARAQALVNTVNTVGVMGKGIALMFKERFADNYRQYAAACKSGQVKTGHMFVTKTTELDGPRWIINFPTK
QHWRSPSQLEWVVEGLQDLRRFLIDNEVKSVAIPPLGAGNGGLDWNHVRPEIERALGDLTEIDITVFEPTRQYQNVAKRA
GIEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERSIERFMPGNNPLALQFEANRYGPYANRLDKLLDKLDGSYL
HCEKRIADADKLDVIWFDDGRKDLVQAYLQSEAKAYLPALEATAELIDGFESPFGMELLATVDWLLTREQVTPTVPALRE
ALKRWPIPGAAQRKTHLFHDQAISIALERLTTSPLCNAVPPQPICVLPA

Download         Length: 1110 bp

>AT38175 NZ_AP024238:c1177539-1176430 [Rhodoferax sp. MIZ03]
ATGCTCAATTTCACAACAGGTAATTTGCTGGAAGCCCGCGCCCAGGCGCTGGTGAACACGGTGAACACCGTCGGCGTGAT
GGGCAAAGGCATTGCGCTGATGTTCAAAGAGCGCTTTGCTGACAACTATCGCCAATACGCCGCTGCTTGCAAAAGCGGAC
AAGTCAAAACCGGCCACATGTTTGTCACCAAGACGACCGAGCTGGACGGCCCGCGCTGGATCATTAACTTTCCCACCAAG
CAGCATTGGCGCTCACCCTCCCAACTGGAATGGGTGGTTGAAGGTTTGCAGGATCTGCGCCGCTTTCTCATCGACAACGA
GGTCAAGTCCGTTGCCATTCCCCCCCTCGGTGCGGGCAATGGCGGGCTGGACTGGAACCACGTCAGGCCGGAGATCGAGC
GTGCATTGGGCGATTTGACTGAGATCGACATCACCGTGTTTGAGCCAACCAGGCAATACCAGAATGTGGCCAAGCGCGCC
GGTATTGAAAAACTGACCCCAGCCCGCGCACTGATTGCCGAGTTGGTCCGCCGCTACTGGGTGCTGGGCATGGAATGCAG
CTTGCTGGAAATCCAAAAGCTGGCCTGGTTTCTGGAGCGCTCCATTGAACGCTTCATGCCAGGCAACAATCCGCTGGCAC
TTCAATTCGAAGCCAACCGGTATGGCCCCTATGCCAACCGCCTGGACAAGCTTTTGGACAAACTCGACGGCAGCTACCTG
CATTGCGAAAAGCGCATTGCCGATGCCGACAAACTTGACGTGATCTGGTTTGATGATGGTCGCAAAGACTTGGTACAAGC
CTATTTGCAGAGCGAAGCCAAGGCTTACCTCCCGGCACTGGAGGCCACCGCCGAGCTGATTGACGGCTTTGAATCTCCCT
TTGGTATGGAGTTGCTGGCAACCGTGGATTGGCTTTTAACCCGCGAGCAGGTTACCCCCACCGTGCCTGCCCTGCGTGAA
GCCCTGAAGCGCTGGCCCATTCCAGGCGCGGCGCAACGCAAGACCCACCTCTTCCATGACCAAGCCATCAGCATTGCGCT
GGAGCGTTTGACCACGTCCCCGCTGTGCAACGCCGTACCACCACAGCCAATCTGCGTTTTGCCTGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References