Detailed information of TA system TA038174

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacT-ataR/DUF1778(antitoxin)
• Location: 1075268..1076019
• Replicon: chromosome
• Accession: NZ_AP024238
• Organism: Rhodoferax sp. MIZ03

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: -
• Locus tag: LDN84_RS05070
• Protein ID: WP_223909373.1
• Coordinates: 1075531..1076019 (+)
• Length: 163 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: LDN84_RS05065
• Protein ID: WP_223912766.1
• Coordinates: 1075268..1075534 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LDN84_RS05030	1071601..1072356	+	756	WP_223909351.1	hypothetical protein	-
LDN84_RS05035 (MIZ03_1070)	1072632..1072856	+	225	WP_223909356.1	addiction module protein	-
LDN84_RS22830	1072869..1073249	+	381	WP_228745496.1	hypothetical protein	-
LDN84_RS05045 (MIZ03_1073)	1073284..1073511	+	228	WP_223909361.1	addiction module protein	-
LDN84_RS05050 (MIZ03_1074)	1073508..1073804	+	297	WP_223909366.1	type II toxin-antitoxin system RelE/ParE family toxin	-
LDN84_RS05055 (MIZ03_1076)	1073995..1074318	+	324	WP_223909369.1	hypothetical protein	-
LDN84_RS05060 (MIZ03_1077)	1074380..1074643	+	264	WP_223909371.1	hypothetical protein	-
LDN84_RS05065 (MIZ03_1079)	1075268..1075534	+	267	WP_223912766.1	DUF1778 domain-containing protein	Antitoxin
LDN84_RS05070 (MIZ03_1080)	1075531..1076019	+	489	WP_223909373.1	GNAT family N-acetyltransferase	Toxin
LDN84_RS05075 (MIZ03_1082)	1077101..1077604	+	504	WP_223909375.1	hypothetical protein	-
LDN84_RS05080 (MIZ03_1083)	1077636..1078072	+	437	Protein_995	transposase	-
LDN84_RS05085 (MIZ03_1085)	1079037..1079567	+	531	WP_223909377.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1055608..1081058	25450

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (38-148)

Antitoxin

• Vibrio phage ICP1, Orf50 (6-80)

Sequences

Toxin

Protein

• Length: 163 a.a.
• Molecular weight: 17604.38 Da
• Isoelectric Point: 9.8397

>T38174 WP_223909373.1 NZ_AP024238:1075531-1076019 [Rhodoferax sp. MIZ03]
MSLGLQAPQPLLATHRCDGFASSEPELDAWLMRRAYANQLSGASRTFVVVDAQQAVVGYYALAAGAVSHPIATPAVRRNM
PDPIPVMVLARLAVDQRAQGQKLGASLLQDAVKRCALVSQHAGIRALLVHALHDRAKQFYEHYGFQASAIHPMTLLLRLQ
QS

Nucleotide

• Length: 489 bp

>T38174 NZ_AP024238:1075531-1076019 [Rhodoferax sp. MIZ03]
ATGAGTCTGGGTTTGCAGGCCCCGCAGCCGCTGCTGGCAACGCATCGCTGCGACGGGTTTGCCAGCTCTGAGCCCGAGCT
TGATGCCTGGCTCATGCGCCGCGCCTACGCCAACCAGCTCAGTGGGGCCAGTCGCACGTTTGTGGTGGTCGATGCGCAGC
AAGCTGTGGTGGGCTACTACGCCTTGGCGGCTGGGGCGGTGTCGCATCCAATCGCCACCCCGGCGGTGCGACGCAACATG
CCAGACCCGATACCGGTCATGGTGCTGGCCAGGCTGGCCGTTGACCAACGCGCCCAAGGTCAAAAGCTGGGTGCATCGCT
GTTGCAAGATGCTGTCAAGCGCTGTGCGCTGGTGTCGCAACATGCGGGTATCCGGGCCTTGCTGGTGCACGCCCTGCATG
ACCGCGCCAAACAGTTTTATGAACACTACGGTTTTCAGGCATCAGCCATTCACCCAATGACTTTATTGCTGCGACTGCAA
CAAAGTTGA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9860.34 Da
• Isoelectric Point: 5.0175

>AT38174 WP_223912766.1 NZ_AP024238:1075268-1075534 [Rhodoferax sp. MIZ03]
MRDAAINLRARPAQRDLIDHAAQLLGKNRSDFMLEAACDKARSVLLDQVFFSLDEAQFQSFVQMLDAPLTANEGLERLMA
VKPVWQAA

Nucleotide

• Length: 267 bp

>AT38174 NZ_AP024238:1075268-1075534 [Rhodoferax sp. MIZ03]
ATGCGTGATGCCGCCATCAATTTACGCGCCAGACCCGCGCAGCGTGATCTGATTGACCACGCCGCCCAGTTGCTGGGCAA
AAACCGGTCTGACTTCATGCTGGAAGCCGCTTGCGACAAAGCTCGCAGCGTTTTGCTTGACCAGGTGTTTTTCAGCTTGG
ACGAAGCCCAGTTTCAAAGCTTTGTCCAGATGCTCGATGCGCCCTTGACTGCCAACGAGGGGCTGGAGCGGCTGATGGCT
GTCAAGCCGGTTTGGCAAGCGGCATGA