Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2076124..2076395 Replicon chromosome
Accession NZ_AP024205
Organism Escherichia coli strain TA8571

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2076254..2076357 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2076124..2076395 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG732_RS10015 2072680..2073342 - 663 WP_063084778.1 exodeoxyribonuclease X -
JG732_RS10020 2073366..2074022 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
JG732_RS10025 2074124..2074354 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JG732_RS10030 2074493..2074867 + 375 WP_000168747.1 CopC domain-containing protein YobA -
JG732_RS10035 2074871..2075743 + 873 WP_000879294.1 copper homeostasis membrane protein CopD -
JG732_RS10040 2075756..2076097 + 342 WP_000976472.1 YebY family protein -
- 2076124..2076395 - 272 - - Antitoxin
- 2076254..2076357 + 104 - - Toxin
JG732_RS10045 2076492..2077148 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
JG732_RS10050 2077149..2077340 - 192 WP_001296140.1 YebW family protein -
JG732_RS10055 2077445..2077681 - 237 WP_001295499.1 DUF1480 family protein -
JG732_RS10060 2077799..2079238 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T38156 NZ_AP024205:2076254-2076357 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT38156 NZ_AP024205:c2076395-2076124 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References