Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 4536885..4538338 Replicon chromosome
Accession NZ_AP024172
Organism Alicycliphilus denitrificans strain I51

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag ALDI51_RS21435 Protein ID WP_201396477.1
Coordinates 4536885..4537736 (-) Length 284 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag ALDI51_RS21440 Protein ID WP_201396478.1
Coordinates 4537733..4538338 (-) Length 202 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ALDI51_RS21415 4532192..4532974 - 783 WP_106447349.1 IS21-like element helper ATPase IstB -
ALDI51_RS21420 4532971..4533978 - 1008 WP_201398426.1 IS21 family transposase -
ALDI51_RS21430 4535515..4536807 - 1293 WP_201396476.1 hypothetical protein -
ALDI51_RS21435 4536885..4537736 - 852 WP_201396477.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
ALDI51_RS21440 4537733..4538338 - 606 WP_201396478.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
ALDI51_RS21445 4538829..4539170 - 342 WP_201396479.1 chorismate mutase -
ALDI51_RS21450 4539167..4540666 - 1500 WP_201396480.1 anthranilate synthase component I -
ALDI51_RS21455 4541009..4542778 + 1770 WP_201396481.1 MCP four helix bundle domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(34-262)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(8-55)


Sequences

Toxin        


Download         Length: 284 a.a.        Molecular weight: 30802.52 Da        Isoelectric Point: 6.8692

>T38084 WP_201396477.1 NZ_AP024172:c4537736-4536885 [Alicycliphilus denitrificans]
MSNSAASIRARLLNVAKAQGVDFNQVLVRFALERILYRLTQSPHANRFLLKGALLFTLWYDMPHRATRDADLLGFGASDL
ESVAQIFREIAAVAVDDGIVFDPASVSVEEIRKEAGYGGVRVVVAGVLAKARCKTQIDVGFGDAVTPGPVDSIYPVLLGD
MPAPRLRAYPSYTVVAEKLHAIALLGMTNSRVKDYFDLSVLLQRETFDTDLLAQAIKATCERRGMVVPAGLPVGLTDEFA
HDSSRQALWQAFVRKNELDPEPLATVVARLRVALEPALNAAAQ

Download         Length: 852 bp

>T38084 NZ_AP024172:c4537736-4536885 [Alicycliphilus denitrificans]
ATGAGCAACAGTGCGGCCTCCATTCGTGCTCGCCTGCTCAACGTGGCCAAGGCGCAAGGCGTGGATTTCAATCAGGTTCT
GGTGCGCTTCGCCCTCGAGCGCATTCTCTACCGTTTGACCCAATCGCCGCATGCAAATCGCTTTCTGCTCAAGGGTGCAC
TACTGTTCACGCTTTGGTACGACATGCCGCATCGGGCTACGCGTGACGCCGACCTGCTGGGCTTCGGTGCGAGCGATCTG
GAATCGGTCGCGCAGATCTTTCGTGAGATCGCAGCCGTCGCTGTGGACGACGGCATCGTGTTCGACCCTGCTTCTGTCAG
CGTCGAAGAAATCCGCAAGGAAGCGGGCTATGGCGGCGTGCGCGTGGTCGTTGCAGGCGTTTTGGCCAAGGCACGCTGCA
AGACGCAGATCGACGTCGGCTTTGGAGATGCCGTTACGCCTGGCCCAGTGGACTCGATCTACCCGGTGCTCTTGGGCGAC
ATGCCTGCACCGCGACTACGAGCCTATCCAAGCTACACCGTTGTCGCGGAAAAGCTTCATGCTATTGCGCTGCTGGGCAT
GACGAACAGCCGCGTGAAGGACTACTTCGACCTGTCGGTGCTATTGCAGCGCGAAACCTTCGATACCGATCTGCTGGCCC
AGGCGATCAAGGCCACCTGCGAGCGGCGCGGCATGGTTGTACCCGCCGGACTGCCGGTCGGCCTCACGGACGAATTCGCG
CACGATTCCTCACGGCAGGCACTGTGGCAGGCATTCGTCAGGAAGAACGAACTCGATCCCGAACCGTTGGCCACTGTTGT
GGCTCGGCTGCGGGTGGCGTTGGAACCAGCGTTGAATGCAGCTGCGCAATAG

Antitoxin


Download         Length: 202 a.a.        Molecular weight: 22353.07 Da        Isoelectric Point: 9.6131

>AT38084 WP_201396478.1 NZ_AP024172:c4538338-4537733 [Alicycliphilus denitrificans]
MVADTHTQRVLDLVHQKGLLRTSDLDAIEAPRVVLTRLISAGLLDKVGRGLYRLPSHEGSEHEGLAVVATKVPQAVFCLL
TALQFHELTTQLPRQVWIAMPRGSHVPRVAYPPLKMVQMTGDVYAAGVEEHQRDGVTLRVYGAAKTVVDCFKHRNKIGLD
VALEALKDARAKKKATADDLWRYAKLCRVANVMRPYLEAIE

Download         Length: 606 bp

>AT38084 NZ_AP024172:c4538338-4537733 [Alicycliphilus denitrificans]
ATGGTCGCCGACACCCACACCCAGCGCGTCCTCGATCTGGTTCATCAGAAGGGGCTGCTGCGCACGAGTGATCTGGATGC
CATTGAAGCACCTCGGGTTGTGCTGACGCGGCTGATATCCGCTGGCCTGCTCGACAAGGTCGGACGCGGCCTCTACCGTT
TGCCCAGTCACGAGGGTTCGGAGCATGAGGGCCTTGCCGTTGTGGCAACCAAGGTGCCGCAGGCCGTGTTCTGCCTGCTG
ACCGCCCTCCAGTTCCACGAACTGACCACGCAGCTACCCAGGCAGGTCTGGATTGCCATGCCGCGCGGCAGCCATGTTCC
GCGCGTCGCCTACCCGCCCCTCAAGATGGTGCAGATGACGGGCGATGTCTACGCCGCTGGCGTCGAGGAGCATCAGCGAG
ATGGCGTGACGCTGCGTGTGTACGGTGCGGCTAAGACGGTCGTGGACTGCTTCAAGCACCGCAACAAGATCGGTTTGGAC
GTGGCGCTGGAGGCGCTGAAGGATGCACGCGCCAAGAAAAAGGCCACGGCGGACGATCTGTGGCGCTACGCGAAGCTTTG
CCGCGTGGCCAATGTGATGCGCCCTTATCTAGAAGCCATCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References