Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4122757..4123391 Replicon chromosome
Accession NZ_AP024172
Organism Alicycliphilus denitrificans strain I51

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ALDI51_RS19500 Protein ID WP_201396213.1
Coordinates 4122987..4123391 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ALDI51_RS19495 Protein ID WP_201396212.1
Coordinates 4122757..4122990 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ALDI51_RS19470 4118395..4118814 + 420 WP_201396207.1 hypothetical protein -
ALDI51_RS19475 4118881..4120227 + 1347 WP_201396208.1 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB -
ALDI51_RS19480 4120419..4121180 - 762 WP_201396209.1 hypothetical protein -
ALDI51_RS19485 4121271..4121795 - 525 WP_201396210.1 pilin -
ALDI51_RS19490 4122019..4122465 + 447 WP_201396211.1 hypothetical protein -
ALDI51_RS19495 4122757..4122990 + 234 WP_201396212.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
ALDI51_RS19500 4122987..4123391 + 405 WP_201396213.1 type II toxin-antitoxin system VapC family toxin Toxin
ALDI51_RS19505 4123465..4124844 - 1380 WP_013722921.1 signal recognition particle protein -
ALDI51_RS19510 4124934..4125731 + 798 WP_094438286.1 cytochrome c biogenesis protein CcsA -
ALDI51_RS19515 4125728..4125955 + 228 WP_201396214.1 hypothetical protein -
ALDI51_RS19520 4125968..4127671 + 1704 WP_094438288.1 HAMP domain-containing histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14973.42 Da        Isoelectric Point: 7.0273

>T38082 WP_201396213.1 NZ_AP024172:4122987-4123391 [Alicycliphilus denitrificans]
VMRYMLDTNICIYVINQRPAHVLPIFNAHHSQMCISEITRFELLSGAYKSKAPHKALYDISTFCAMLDVLPLDAAACDHA
AQIRAMLEQKGQKIGPFDTLIAGHARSLAAILVTNNVREFERVGSLMIEDWTQG

Download         Length: 405 bp

>T38082 NZ_AP024172:4122987-4123391 [Alicycliphilus denitrificans]
GTGATGCGCTACATGCTCGACACCAACATTTGCATCTACGTCATCAACCAGCGGCCCGCTCATGTGCTGCCCATCTTCAA
TGCGCATCACAGCCAGATGTGCATCTCCGAGATCACGCGTTTCGAGCTTTTGAGCGGCGCCTACAAGTCCAAGGCGCCGC
ACAAGGCCCTGTACGACATCAGTACCTTTTGCGCCATGCTCGATGTGCTGCCACTCGATGCCGCCGCCTGCGACCATGCG
GCGCAGATTCGCGCCATGCTGGAGCAAAAGGGCCAGAAGATCGGCCCCTTCGATACGCTCATCGCGGGCCATGCGCGCAG
CCTCGCCGCCATCCTCGTCACCAACAACGTGCGCGAGTTCGAGCGCGTCGGCAGCCTGATGATCGAGGACTGGACGCAGG
GCTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8665.89 Da        Isoelectric Point: 6.2096

>AT38082 WP_201396212.1 NZ_AP024172:4122757-4122990 [Alicycliphilus denitrificans]
MVHSKLFLNHKSQSVRFHKSVAFAPEVQEVTIVAVGNTRIIAPVGKTWDAWFAQPVDDDALLPERDQPPMQEREALA

Download         Length: 234 bp

>AT38082 NZ_AP024172:4122757-4122990 [Alicycliphilus denitrificans]
ATGGTCCACTCCAAGCTGTTCCTGAATCACAAGAGCCAGTCCGTCCGCTTTCACAAGTCGGTGGCATTCGCACCCGAGGT
GCAGGAGGTCACCATTGTGGCGGTGGGCAACACCCGCATCATTGCGCCTGTCGGCAAGACCTGGGATGCCTGGTTTGCAC
AGCCGGTGGATGATGACGCCCTGCTGCCCGAGCGCGATCAGCCCCCCATGCAAGAGCGAGAGGCGCTGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References