38042

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 1026114..1026706 Replicon chromosome
Accession NZ_AP024145
Organism Methylobacterium indicum strain VL1

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag miv_RS04670 Protein ID WP_207181656.1
Coordinates 1026114..1026368 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag miv_RS04675 Protein ID WP_207181658.1
Coordinates 1026365..1026706 (+) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
miv_RS04655 1021825..1022940 + 1116 WP_207181650.1 magnesium chelatase ATPase subunit I -
miv_RS04660 1022937..1024691 + 1755 WP_207181652.1 magnesium chelatase subunit D -
miv_RS04665 1024699..1025604 + 906 WP_207181654.1 alpha/beta fold hydrolase -
miv_RS04670 1026114..1026368 + 255 WP_207181656.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
miv_RS04675 1026365..1026706 + 342 WP_207181658.1 helix-turn-helix domain-containing protein Antitoxin
miv_RS04680 1026803..1028329 + 1527 WP_207181660.1 phytoene desaturase -
miv_RS04685 1028310..1029380 + 1071 WP_207181662.1 phytoene/squalene synthase family protein -
miv_RS04690 1029377..1029526 + 150 WP_207183694.1 hypothetical protein -
miv_RS04695 1029617..1030633 + 1017 WP_207183398.1 DUF3616 domain-containing protein -
miv_RS04700 1030665..1030982 - 318 WP_207181664.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-68)

Antitoxin

HigA2-like, helix-turn-helix domain

(16-95)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9257.72 Da        Isoelectric Point: 10.3181

>T38042 WP_207181656.1 NZ_AP024145:1026114-1026368 [Methylobacterium indicum]
MAARFPARVVYRGRGVLEVVESDVSGTYRAVYTVRFADCVYVLHCFQKKSTKGIATQQHDVELIKARLHAAAADHAKRIG
GAKP

Download         Length: 255 bp

>T38042 NZ_AP024145:1026114-1026368 [Methylobacterium indicum]
TTGGCTGCACGGTTCCCGGCCAGGGTCGTGTACCGTGGTCGCGGCGTTCTCGAAGTCGTCGAAAGCGACGTGAGCGGGAC
CTATCGGGCCGTCTACACGGTTCGCTTCGCCGACTGCGTGTACGTTCTGCATTGCTTCCAGAAGAAGTCGACCAAGGGTA
TCGCGACGCAACAGCACGACGTCGAGTTGATCAAAGCTCGGCTGCACGCGGCCGCGGCGGATCATGCCAAGCGCATTGGA
GGAGCCAAGCCATGA

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12273.94 Da        Isoelectric Point: 4.5641

>AT38042 WP_207181658.1 NZ_AP024145:1026365-1026706 [Methylobacterium indicum]
MNDSDEIEVVEGSGNVFADLELPDAGEWLLKADLAAELRRLIGERNLTQTRAAAILGIAQPDLSRLLRGSLRGCSVERLM
GFLTAFDRDVEVTVRPRSGPGDRGRITVTLAPN

Download         Length: 342 bp

>AT38042 NZ_AP024145:1026365-1026706 [Methylobacterium indicum]
ATGAACGACTCCGACGAGATCGAGGTCGTGGAGGGTAGCGGAAACGTCTTTGCGGATCTCGAACTTCCCGATGCGGGAGA
ATGGCTTCTCAAGGCCGATCTGGCGGCCGAGCTCCGGCGGCTGATCGGCGAGCGGAACCTGACCCAGACCCGGGCGGCCG
CGATCCTCGGTATCGCACAGCCCGATCTATCCAGGCTGCTGCGGGGAAGCCTGCGCGGATGCTCGGTCGAGCGGCTGATG
GGCTTCCTCACCGCCTTCGACCGGGATGTCGAGGTGACGGTACGCCCTCGCTCCGGGCCTGGTGATCGGGGGCGGATCAC
CGTCACGCTGGCGCCGAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References