Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2133265..2133536 Replicon chromosome
Accession NZ_AP024114
Organism Escherichia coli strain JML285

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2133395..2133498 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2133265..2133536 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFF71_RS10285 2129820..2130482 - 663 WP_000944256.1 exodeoxyribonuclease X -
FFF71_RS10290 2130506..2131162 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
FFF71_RS10295 2131264..2131494 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FFF71_RS10300 2131633..2132007 + 375 WP_000204699.1 CopC domain-containing protein YobA -
FFF71_RS10305 2132011..2132883 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
FFF71_RS10310 2132896..2133237 + 342 WP_000976492.1 YebY family protein -
- 2133265..2133536 - 272 - - Antitoxin
- 2133395..2133498 + 104 - - Toxin
FFF71_RS10315 2133633..2134289 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
FFF71_RS10320 2134290..2134481 - 192 WP_001296140.1 YebW family protein -
FFF71_RS10325 2134586..2134822 - 237 WP_001295499.1 YebV family protein -
FFF71_RS10330 2134940..2136379 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T37909 NZ_AP024114:2133395-2133498 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT37909 NZ_AP024114:c2133536-2133265 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References