Detailed information of TA system TA037859

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-pasA/RelE-HTH
• Location: 2448241..2448712
• Replicon: chromosome
• Accession: NZ_AP024109
• Organism: Mesorhizobium sp. J8

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: MJ8_RS11235
• Protein ID: WP_201414429.1
• Coordinates: 2448446..2448712 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: MJ8_RS11230
• Protein ID: WP_127864915.1
• Coordinates: 2448241..2448462 (+)
• Length: 74 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MJ8_RS11220	2445029..2446957	-	1929	WP_201414427.1	LTA synthase family protein	-
MJ8_RS11225	2447235..2448176	+	942	WP_201414428.1	ACP S-malonyltransferase	-
MJ8_RS11230	2448241..2448462	+	222	WP_127864915.1	ribbon-helix-helix protein, CopG family	Antitoxin
MJ8_RS11235	2448446..2448712	+	267	WP_201414429.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
MJ8_RS11240	2448750..2449487	+	738	WP_201414430.1	3-oxoacyl-[acyl-carrier-protein] reductase	-
MJ8_RS11245	2449710..2449946	+	237	WP_006203723.1	acyl carrier protein	-
MJ8_RS11250	2449981..2451243	+	1263	WP_201414431.1	beta-ketoacyl-ACP synthase II	-
MJ8_RS11255	2451401..2452654	+	1254	WP_201414432.1	endolytic transglycosylase MltG	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-87)

Antitoxin

• Ribbon-helix-helix protein, CopG (3-39)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10439.05 Da
• Isoelectric Point: 10.1808

>T37859 WP_201414429.1 NZ_AP024109:2448446-2448712 [Mesorhizobium sp. J8]
VAWTLEYARSARKFVEKLDPHTRNRIRDFIENRLAELDNPRELGKPLKGPLATFWRYRVGDYRIICDVQDTRLVILVVTI
GHRGDVYR

Nucleotide

• Length: 267 bp

>T37859 NZ_AP024109:2448446-2448712 [Mesorhizobium sp. J8]
GTGGCCTGGACGCTTGAGTATGCTCGTTCGGCTCGCAAGTTTGTCGAGAAACTAGACCCGCACACACGCAACCGCATCCG
CGATTTCATCGAAAACCGACTTGCCGAGCTCGACAATCCGCGTGAGCTGGGCAAACCACTGAAAGGTCCGTTGGCGACAT
TCTGGAGATACCGAGTTGGGGACTACCGGATTATCTGCGATGTGCAAGACACGCGGCTGGTCATTCTTGTTGTGACGATC
GGCCATCGAGGCGACGTCTACAGATAG

Antitoxin

Protein

• Length: 74 a.a.
• Molecular weight: 8563.65 Da
• Isoelectric Point: 4.3543

>AT37859 WP_127864915.1 NZ_AP024109:2448241-2448462 [Mesorhizobium sp. J8]
MPTSIRLAPEIEERLDFLAAKTGRSKAYYLRELIERGLEDVEDYYLAAEVLERIRRGEEDVVKSEDFWRGLDA

Nucleotide

• Length: 222 bp

>AT37859 NZ_AP024109:2448241-2448462 [Mesorhizobium sp. J8]
ATGCCGACATCCATCCGCCTGGCACCAGAGATTGAAGAACGCCTGGACTTTCTTGCCGCCAAGACCGGCCGCAGCAAAGC
CTATTATCTGCGTGAACTCATTGAGCGCGGGCTCGAAGACGTGGAGGACTATTATCTTGCTGCCGAGGTGCTTGAGCGGA
TCAGGCGAGGTGAGGAGGATGTCGTAAAGAGCGAGGATTTCTGGCGTGGCCTGGACGCTTGA