Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 52584..53113 Replicon plasmid pMAFF241647
Accession NZ_AP024106
Organism Ralstonia solanacearum strain MAFF 241647

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JK149_RS17995 Protein ID WP_016722340.1
Coordinates 52886..53113 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JK149_RS17990 Protein ID WP_016722339.1
Coordinates 52584..52889 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JK149_RS17955 47698..47979 - 282 WP_016722336.1 hypothetical protein -
JK149_RS17960 48110..48394 - 285 WP_043897982.1 hypothetical protein -
JK149_RS17965 48727..48914 + 188 Protein_44 IS5/IS1182 family transposase -
JK149_RS17970 49238..49462 + 225 WP_144061921.1 hypothetical protein -
JK149_RS17975 49959..50267 + 309 WP_043897983.1 hypothetical protein -
JK149_RS17980 50601..50888 - 288 WP_043898169.1 barstar family protein -
JK149_RS17985 51058..52371 - 1314 WP_043897984.1 metabolite/H+ symporter -
JK149_RS17990 52584..52889 - 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
JK149_RS17995 52886..53113 - 228 WP_016722340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JK149_RS18000 53268..54467 - 1200 WP_016726513.1 MFS transporter -
JK149_RS18005 54594..55415 - 822 WP_011003398.1 GntR family transcriptional regulator -
JK149_RS18010 55593..56144 - 552 WP_011003399.1 helix-turn-helix transcriptional regulator -
JK149_RS18015 56277..56876 + 600 WP_016722344.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cyaB / flgC / flgG / fliM / fliG / fliI / acrB / htpB / adeG / cheY / cheB / cheW / motA 1..2077684 2077684


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-67)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8566.85 Da        Isoelectric Point: 7.2789

>T37853 WP_016722340.1 NZ_AP024106:c53113-52886 [Ralstonia solanacearum]
VRIDRLQMGHPGNMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCGGDKSTQETDIRRAIDLSRRLDVDDME

Download         Length: 228 bp

>T37853 NZ_AP024106:c53113-52886 [Ralstonia solanacearum]
GTGCGCATCGACCGCCTGCAGATGGGCCACCCAGGCAACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCGA
TCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCGA
CGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT37853 WP_016722339.1 NZ_AP024106:c52889-52584 [Ralstonia solanacearum]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT37853 NZ_AP024106:c52889-52584 [Ralstonia solanacearum]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAGGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References