Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 49931..50460 Replicon plasmid pMAFF211471
Accession NZ_AP024098
Organism Ralstonia solanacearum strain MAFF 211471

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MAFF211471_RS18765 Protein ID WP_016722340.1
Coordinates 50233..50460 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MAFF211471_RS18760 Protein ID WP_016722339.1
Coordinates 49931..50236 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MAFF211471_RS18725 45193..45342 + 150 WP_155738951.1 hypothetical protein -
MAFF211471_RS18730 45431..45916 + 486 WP_016726511.1 hypothetical protein -
MAFF211471_RS18735 46247..46528 - 282 WP_016722336.1 hypothetical protein -
MAFF211471_RS18740 46659..46943 - 285 WP_011003391.1 hypothetical protein -
MAFF211471_RS18745 47248..47465 + 218 Protein_45 transposase -
MAFF211471_RS18750 47632..48300 + 669 WP_038938024.1 hypothetical protein -
MAFF211471_RS18755 48405..49718 - 1314 WP_038938025.1 metabolite/H+ symporter -
MAFF211471_RS18760 49931..50236 - 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
MAFF211471_RS18765 50233..50460 - 228 WP_016722340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MAFF211471_RS18770 50615..51814 - 1200 WP_016726513.1 MFS transporter -
MAFF211471_RS18775 51941..52762 - 822 WP_021154993.1 GntR family transcriptional regulator -
MAFF211471_RS18780 52940..53491 - 552 WP_016722343.1 helix-turn-helix transcriptional regulator -
MAFF211471_RS18785 53624..54223 + 600 WP_016722344.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - motA / cheW / cheB / cheY / adeG / htpB / acrB / fliI / fliG / fliM / flgG / flgC / cyaB 1..2139380 2139380
- flank IS/Tn - - 44231..45196 965


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-67)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8566.85 Da        Isoelectric Point: 7.2789

>T37835 WP_016722340.1 NZ_AP024098:c50460-50233 [Ralstonia solanacearum]
VRIDRLQMGHPGNMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCGGDKSTQETDIRRAIDLSRRLDVDDME

Download         Length: 228 bp

>T37835 NZ_AP024098:c50460-50233 [Ralstonia solanacearum]
GTGCGCATCGACCGCCTGCAGATGGGCCACCCAGGCAACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCGA
TCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCGA
CGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT37835 WP_016722339.1 NZ_AP024098:c50236-49931 [Ralstonia solanacearum]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT37835 NZ_AP024098:c50236-49931 [Ralstonia solanacearum]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAGGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References