Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1511972..1512573 Replicon chromosome
Accession NZ_AP024094
Organism Jeongeupia sp. HS-3

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag JLC71_RS07155 Protein ID WP_200918058.1
Coordinates 1512283..1512573 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag JLC71_RS07150 Protein ID WP_200918290.1
Coordinates 1511972..1512265 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLC71_RS07130 1507525..1508274 - 750 WP_200918054.1 disulfide bond formation protein B -
JLC71_RS07135 1508218..1509687 + 1470 WP_200918055.1 IMP dehydrogenase -
JLC71_RS07140 1509875..1511158 + 1284 WP_200918056.1 tyrosine-type recombinase/integrase -
JLC71_RS07145 1511698..1511943 + 246 WP_200918057.1 hypothetical protein -
JLC71_RS07150 1511972..1512265 - 294 WP_200918290.1 putative addiction module antidote protein Antitoxin
JLC71_RS07155 1512283..1512573 - 291 WP_200918058.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JLC71_RS07160 1512849..1514033 + 1185 WP_200918059.1 hypothetical protein -
JLC71_RS07165 1514090..1514296 + 207 WP_200918060.1 helix-turn-helix domain-containing protein -
JLC71_RS07170 1514293..1514520 + 228 WP_200918061.1 AlpA family transcriptional regulator -
JLC71_RS07175 1514517..1514732 + 216 WP_200918062.1 hypothetical protein -
JLC71_RS07180 1514729..1515250 + 522 WP_200918063.1 hypothetical protein -
JLC71_RS07185 1515237..1515476 + 240 WP_200918064.1 hypothetical protein -
JLC71_RS07190 1515690..1516703 + 1014 WP_200918065.1 toprim domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-89)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10778.41 Da        Isoelectric Point: 7.1653

>T37832 WP_200918058.1 NZ_AP024094:c1512573-1512283 [Jeongeupia sp. HS-3]
MKTILTTDIFDAWLAGLRDKQAARRIHMRIDRAEDGNFGDCEPVGEGVAEMRIHYGPGYRVYFAQRGMEIVILLAGGDKS
TQPKDIKTALELARQL

Download         Length: 291 bp

>T37832 NZ_AP024094:c1512573-1512283 [Jeongeupia sp. HS-3]
ATGAAGACCATCCTCACTACCGACATTTTCGATGCTTGGCTGGCCGGACTACGGGATAAGCAGGCCGCGCGCAGAATCCA
TATGCGGATTGACCGGGCCGAAGACGGCAACTTCGGCGACTGCGAACCGGTCGGTGAAGGCGTGGCAGAAATGCGTATTC
ACTACGGGCCGGGTTATCGGGTGTACTTCGCGCAGCGCGGCATGGAAATCGTGATTCTGCTGGCGGGCGGGGATAAATCC
ACCCAGCCCAAGGACATCAAAACCGCGCTTGAGCTGGCGCGGCAACTGTAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10417.97 Da        Isoelectric Point: 7.1656

>AT37832 WP_200918290.1 NZ_AP024094:c1512265-1511972 [Jeongeupia sp. HS-3]
IKLRKWDSAEHLKTEEDMLMYLDACLEEAGDDAAFIAKALGTIARARGMTQLAKDTGLGRESLYKALSGEGNPSFATILK
VTRALGISLHAQARPAG

Download         Length: 294 bp

>AT37832 NZ_AP024094:c1512265-1511972 [Jeongeupia sp. HS-3]
ATCAAACTACGTAAGTGGGACAGCGCCGAGCACCTCAAAACTGAGGAAGACATGCTGATGTATCTCGACGCCTGCTTGGA
AGAAGCCGGCGATGATGCCGCTTTCATTGCCAAGGCGCTCGGCACTATCGCCCGCGCGCGCGGCATGACCCAGCTCGCCA
AGGACACCGGTCTCGGCCGAGAAAGCCTATATAAAGCGCTGTCCGGCGAGGGAAACCCTAGCTTTGCAACCATCCTGAAG
GTAACGCGGGCACTGGGCATCTCGTTGCACGCGCAGGCACGGCCGGCAGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References