Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 283861..284396 Replicon plasmid pVNTG1
Accession NZ_AP024089
Organism Vibrio nigripulchritudo strain TUMSAT-TG-2018

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag VNTUMSATTG_RS29690 Protein ID WP_200768858.1
Coordinates 283861..284136 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag VNTUMSATTG_RS29695 Protein ID WP_200768859.1
Coordinates 284136..284396 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VNTUMSATTG_RS29675 279694..281421 - 1728 WP_200768857.1 AAA family ATPase -
VNTUMSATTG_RS29680 282228..283243 + 1016 Protein_257 IS3 family transposase -
VNTUMSATTG_RS29685 283238..283810 - 573 Protein_258 ATP-dependent helicase -
VNTUMSATTG_RS29690 283861..284136 - 276 WP_200768858.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
VNTUMSATTG_RS29695 284136..284396 - 261 WP_200768859.1 ribbon-helix-helix domain-containing protein Antitoxin
VNTUMSATTG_RS29700 284601..285137 + 537 WP_200768860.1 recombinase family protein -
VNTUMSATTG_RS29705 285158..288034 + 2877 Protein_262 Tn3 family transposase -
VNTUMSATTG_RS29710 288425..288946 - 522 WP_200768861.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..351712 351712
- inside IScluster/Tn - - 268332..288034 19702


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-41)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10718.34 Da        Isoelectric Point: 8.4198

>T37828 WP_200768858.1 NZ_AP024089:c284136-283861 [Vibrio nigripulchritudo]
MEIKWTSKALSDLSRLYEFLALADAIAAAKTVRSLTSAPDILSDQPRLGERLDAFEPREVRRLLVGSYEMRYEIQEYTLY
VLRIWHTREKR

Download         Length: 276 bp

>T37828 NZ_AP024089:c284136-283861 [Vibrio nigripulchritudo]
ATGGAAATAAAATGGACCAGTAAAGCCCTTTCCGATTTAAGCCGACTCTATGAATTCCTTGCCCTCGCAGATGCCATCGC
TGCGGCAAAGACAGTTCGCTCATTGACCAGTGCGCCTGACATACTGTCAGATCAGCCAAGACTGGGGGAGCGGCTTGATG
CTTTTGAGCCCAGGGAAGTTCGCAGGCTTTTGGTTGGCAGCTATGAAATGCGATATGAAATACAGGAATATACCCTGTAT
GTGCTTCGTATCTGGCATACGCGAGAGAAGCGCTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9730.01 Da        Isoelectric Point: 5.1408

>AT37828 WP_200768859.1 NZ_AP024089:c284396-284136 [Vibrio nigripulchritudo]
MNTKVVTAHVPLQLADKVDELAQRLERSKAWVVKQALADWVVMEEERHKLTLEALADVDNDRVTDHQSVKAWAESLGSES
PKDVPR

Download         Length: 261 bp

>AT37828 NZ_AP024089:c284396-284136 [Vibrio nigripulchritudo]
ATGAATACCAAGGTTGTCACTGCACATGTTCCTTTGCAGCTAGCTGATAAAGTTGATGAGTTAGCACAGCGTCTCGAACG
CTCTAAAGCCTGGGTTGTCAAACAGGCTCTGGCGGATTGGGTCGTCATGGAAGAAGAGCGTCATAAACTGACACTGGAAG
CGTTGGCTGATGTTGACAATGACCGGGTTACTGATCACCAGTCTGTTAAGGCCTGGGCAGAAAGTTTGGGGAGTGAGTCT
CCCAAGGACGTGCCAAGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References