Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 140839..141339 Replicon plasmid pVNTG1
Accession NZ_AP024089
Organism Vibrio nigripulchritudo strain TUMSAT-TG-2018

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag VNTUMSATTG_RS29000 Protein ID WP_200768978.1
Coordinates 140839..141093 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag VNTUMSATTG_RS29005 Protein ID WP_200768979.1
Coordinates 141094..141339 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VNTUMSATTG_RS28970 135859..136794 - 936 WP_200768974.1 LysR family transcriptional regulator -
VNTUMSATTG_RS28975 137207..137575 - 369 WP_200768975.1 hypothetical protein -
VNTUMSATTG_RS28980 137720..138298 - 579 WP_200768976.1 DUF2913 family protein -
VNTUMSATTG_RS28985 138635..139453 - 819 Protein_118 NupC/NupG family nucleoside CNT transporter -
VNTUMSATTG_RS28990 139619..139891 - 273 Protein_119 helix-turn-helix domain-containing protein -
VNTUMSATTG_RS28995 140079..140414 - 336 WP_200768977.1 hypothetical protein -
VNTUMSATTG_RS29000 140839..141093 - 255 WP_200768978.1 Txe/YoeB family addiction module toxin Toxin
VNTUMSATTG_RS29005 141094..141339 - 246 WP_200768979.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
VNTUMSATTG_RS29010 142020..142658 - 639 WP_200768980.1 phosphatidylinositol kinase -
VNTUMSATTG_RS29015 142675..142863 + 189 WP_200768981.1 hypothetical protein -
VNTUMSATTG_RS29020 143353..144336 + 984 WP_200768982.1 patatin-like phospholipase family protein -
VNTUMSATTG_RS29025 144352..145692 + 1341 WP_200768983.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..351712 351712


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10085.46 Da        Isoelectric Point: 9.7319

>T37825 WP_200768978.1 NZ_AP024089:c141093-140839 [Vibrio nigripulchritudo]
VNLLFTSHAWEDYQYWQSQDKKTLKRINKLIKDAQRTPDNGIGKPERLKGNLSGCWSRRIDSEHRMVYLFNEDTLTIIAL
RYHY

Download         Length: 255 bp

>T37825 NZ_AP024089:c141093-140839 [Vibrio nigripulchritudo]
GTGAATCTGTTGTTTACTTCTCACGCTTGGGAAGATTATCAATACTGGCAGTCTCAGGATAAAAAGACTCTAAAGAGAAT
AAATAAATTAATCAAAGATGCTCAAAGAACCCCAGATAATGGGATAGGTAAACCTGAAAGACTGAAAGGGAATCTATCTG
GCTGCTGGTCTAGACGAATAGACAGCGAGCACCGAATGGTTTACCTCTTCAATGAAGATACGCTAACAATAATAGCACTT
CGGTATCACTACTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9357.44 Da        Isoelectric Point: 4.7672

>AT37825 WP_200768979.1 NZ_AP024089:c141339-141094 [Vibrio nigripulchritudo]
MNFINYTEARSRLKQVFDSVVDDCDQVTIHRRDSENVVVMSESEFNSWKETVYLLSNPNNSKRLMESLAQASNGEVVKKD
I

Download         Length: 246 bp

>AT37825 NZ_AP024089:c141339-141094 [Vibrio nigripulchritudo]
ATGAACTTTATAAATTATACCGAGGCAAGGTCTAGGCTTAAGCAAGTCTTTGATAGTGTTGTCGATGATTGTGATCAGGT
TACAATACATAGGCGTGACTCTGAAAATGTTGTGGTAATGAGCGAATCTGAGTTTAATTCTTGGAAAGAAACTGTTTATC
TACTGTCCAATCCAAACAATTCAAAAAGACTTATGGAGTCCTTAGCCCAAGCCAGTAATGGTGAAGTGGTTAAAAAGGAT
ATCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References