Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 5367451..5367595 | Replicon | chromosome |
| Accession | NZ_AP023453 | ||
| Organism | Klebsiella pneumoniae strain M941 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 5367487..5367589 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 5367451..5367595 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JLF44_RS26225 | 5362581..5364641 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| JLF44_RS26230 | 5364645..5365304 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| JLF44_RS26235 | 5365383..5365613 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| JLF44_RS26240 | 5365726..5366100 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| JLF44_RS26245 | 5366104..5366973 | + | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| JLF44_RS26250 | 5366990..5367328 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 5367451..5367595 | - | 145 | - | - | Antitoxin |
| - | 5367487..5367589 | + | 103 | - | - | Toxin |
| JLF44_RS26255 | 5367722..5368081 | - | 360 | WP_077253379.1 | tyrosine-type recombinase/integrase | - |
| JLF44_RS26260 | 5368080..5368559 | + | 480 | WP_032419797.1 | lysis protein | - |
| JLF44_RS26265 | 5369348..5370853 | + | 1506 | WP_020956680.1 | hypothetical protein | - |
| JLF44_RS26270 | 5371103..5371531 | - | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| JLF44_RS26275 | 5371541..5371822 | - | 282 | WP_032419786.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 5362614..5389893 | 27279 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T37810 NZ_AP023453:5367487-5367589 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT37810 NZ_AP023453:c5367595-5367451 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
