Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | yfjZ-ypjF/CbtA-CbeA |
Location | 859183..859886 | Replicon | chromosome |
Accession | NZ_AP023452 | ||
Organism | Citrobacter koseri strain MPUCK001 |
Toxin (Protein)
Gene name | ypjF | Uniprot ID | - |
Locus tag | MPUCK001_RS03945 | Protein ID | WP_032728834.1 |
Coordinates | 859545..859886 (+) | Length | 114 a.a. |
Antitoxin (Protein)
Gene name | yfjZ | Uniprot ID | - |
Locus tag | MPUCK001_RS03940 | Protein ID | WP_096810298.1 |
Coordinates | 859183..859524 (+) | Length | 114 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MPUCK001_RS03910 | 854979..855854 | + | 876 | WP_114262838.1 | GTPase family protein | - |
MPUCK001_RS03915 | 856163..856627 | + | 465 | WP_114262839.1 | hypothetical protein | - |
MPUCK001_RS03920 | 856729..857202 | + | 474 | WP_190286928.1 | hypothetical protein | - |
MPUCK001_RS03925 | 857322..858143 | + | 822 | WP_190286929.1 | DUF945 domain-containing protein | - |
MPUCK001_RS03930 | 858174..858617 | + | 444 | WP_190286930.1 | antirestriction protein | - |
MPUCK001_RS03935 | 858630..859172 | + | 543 | WP_190286931.1 | DNA repair protein RadC | - |
MPUCK001_RS03940 | 859183..859524 | + | 342 | WP_096810298.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin |
MPUCK001_RS03945 | 859545..859886 | + | 342 | WP_032728834.1 | TA system toxin CbtA family protein | Toxin |
MPUCK001_RS03950 | 860145..861152 | + | 1008 | WP_049017154.1 | restriction endonuclease | - |
MPUCK001_RS03955 | 862175..863545 | + | 1371 | WP_049010418.1 | tyrosine phenol-lyase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 114 a.a. Molecular weight: 12777.71 Da Isoelectric Point: 7.1648
>T37784 WP_032728834.1 NZ_AP023452:859545-859886 [Citrobacter koseri]
MKTLPATTPQAATLCLSPVAVWQMLLARLLEQHYGLTLNDTPFSDETVIQEHIDAGITLADAVNFLVEKYELVRIDRRGF
NWQEQSPYLRAVDILRARQATGLLKRNRISAAQ
MKTLPATTPQAATLCLSPVAVWQMLLARLLEQHYGLTLNDTPFSDETVIQEHIDAGITLADAVNFLVEKYELVRIDRRGF
NWQEQSPYLRAVDILRARQATGLLKRNRISAAQ
Download Length: 342 bp
>T37784 NZ_AP023452:859545-859886 [Citrobacter koseri]
ATGAAAACTCTACCTGCAACAACTCCGCAGGCGGCGACGCTATGTCTATCGCCCGTGGCAGTGTGGCAAATGCTGCTTGC
ACGCCTGCTGGAACAACATTATGGCCTGACACTCAACGACACACCATTCAGTGATGAAACGGTAATTCAGGAACATATCG
ATGCCGGTATAACTTTGGCCGATGCCGTTAACTTTTTGGTAGAAAAGTACGAACTGGTTCGTATCGATCGCAGGGGATTC
AACTGGCAGGAACAGTCCCCATATCTGCGGGCAGTCGATATTCTGCGGGCGCGGCAGGCAACTGGTTTATTGAAAAGAAA
TCGTATTAGCGCGGCACAGTGA
ATGAAAACTCTACCTGCAACAACTCCGCAGGCGGCGACGCTATGTCTATCGCCCGTGGCAGTGTGGCAAATGCTGCTTGC
ACGCCTGCTGGAACAACATTATGGCCTGACACTCAACGACACACCATTCAGTGATGAAACGGTAATTCAGGAACATATCG
ATGCCGGTATAACTTTGGCCGATGCCGTTAACTTTTTGGTAGAAAAGTACGAACTGGTTCGTATCGATCGCAGGGGATTC
AACTGGCAGGAACAGTCCCCATATCTGCGGGCAGTCGATATTCTGCGGGCGCGGCAGGCAACTGGTTTATTGAAAAGAAA
TCGTATTAGCGCGGCACAGTGA
Antitoxin
Download Length: 114 a.a. Molecular weight: 12758.31 Da Isoelectric Point: 5.0491
>AT37784 WP_096810298.1 NZ_AP023452:859183-859524 [Citrobacter koseri]
MKSTGSENDSFLQWGLNRNVTPCFGARLVQEGNQLHYLADRVSITGEFSNAESLKLDEVFPRFISQMESMLTTSEMNPRY
AHCVTLYHNGFTCEADTLGSCGYVYIAVYPTQR
MKSTGSENDSFLQWGLNRNVTPCFGARLVQEGNQLHYLADRVSITGEFSNAESLKLDEVFPRFISQMESMLTTSEMNPRY
AHCVTLYHNGFTCEADTLGSCGYVYIAVYPTQR
Download Length: 342 bp
>AT37784 NZ_AP023452:859183-859524 [Citrobacter koseri]
ATGAAATCTACTGGCTCAGAGAACGATTCATTTCTCCAGTGGGGGCTGAATCGTAATGTGACGCCTTGCTTTGGCGCTCG
TCTGGTACAGGAGGGAAACCAACTGCACTATCTGGCTGACCGGGTCAGCATTACCGGTGAATTCAGTAACGCAGAATCTT
TGAAGTTGGATGAAGTATTCCCACGTTTTATCAGCCAGATGGAATCGATGTTGACCACTAGTGAAATGAATCCTCGCTAT
GCCCACTGCGTCACCCTGTACCACAACGGTTTCACCTGCGAAGCCGATACACTTGGCAGTTGCGGCTATGTATACATCGC
CGTTTACCCCACTCAACGTTAA
ATGAAATCTACTGGCTCAGAGAACGATTCATTTCTCCAGTGGGGGCTGAATCGTAATGTGACGCCTTGCTTTGGCGCTCG
TCTGGTACAGGAGGGAAACCAACTGCACTATCTGGCTGACCGGGTCAGCATTACCGGTGAATTCAGTAACGCAGAATCTT
TGAAGTTGGATGAAGTATTCCCACGTTTTATCAGCCAGATGGAATCGATGTTGACCACTAGTGAAATGAATCCTCGCTAT
GCCCACTGCGTCACCCTGTACCACAACGGTTTCACCTGCGAAGCCGATACACTTGGCAGTTGCGGCTATGTATACATCGC
CGTTTACCCCACTCAACGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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