Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 859183..859886 Replicon chromosome
Accession NZ_AP023452
Organism Citrobacter koseri strain MPUCK001

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag MPUCK001_RS03945 Protein ID WP_032728834.1
Coordinates 859545..859886 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag MPUCK001_RS03940 Protein ID WP_096810298.1
Coordinates 859183..859524 (+) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPUCK001_RS03910 854979..855854 + 876 WP_114262838.1 GTPase family protein -
MPUCK001_RS03915 856163..856627 + 465 WP_114262839.1 hypothetical protein -
MPUCK001_RS03920 856729..857202 + 474 WP_190286928.1 hypothetical protein -
MPUCK001_RS03925 857322..858143 + 822 WP_190286929.1 DUF945 domain-containing protein -
MPUCK001_RS03930 858174..858617 + 444 WP_190286930.1 antirestriction protein -
MPUCK001_RS03935 858630..859172 + 543 WP_190286931.1 DNA repair protein RadC -
MPUCK001_RS03940 859183..859524 + 342 WP_096810298.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
MPUCK001_RS03945 859545..859886 + 342 WP_032728834.1 TA system toxin CbtA family protein Toxin
MPUCK001_RS03950 860145..861152 + 1008 WP_049017154.1 restriction endonuclease -
MPUCK001_RS03955 862175..863545 + 1371 WP_049010418.1 tyrosine phenol-lyase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-109)

Antitoxin

Antitoxin CbeA

(13-112)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12777.71 Da        Isoelectric Point: 7.1648

>T37784 WP_032728834.1 NZ_AP023452:859545-859886 [Citrobacter koseri]
MKTLPATTPQAATLCLSPVAVWQMLLARLLEQHYGLTLNDTPFSDETVIQEHIDAGITLADAVNFLVEKYELVRIDRRGF
NWQEQSPYLRAVDILRARQATGLLKRNRISAAQ

Download         Length: 342 bp

>T37784 NZ_AP023452:859545-859886 [Citrobacter koseri]
ATGAAAACTCTACCTGCAACAACTCCGCAGGCGGCGACGCTATGTCTATCGCCCGTGGCAGTGTGGCAAATGCTGCTTGC
ACGCCTGCTGGAACAACATTATGGCCTGACACTCAACGACACACCATTCAGTGATGAAACGGTAATTCAGGAACATATCG
ATGCCGGTATAACTTTGGCCGATGCCGTTAACTTTTTGGTAGAAAAGTACGAACTGGTTCGTATCGATCGCAGGGGATTC
AACTGGCAGGAACAGTCCCCATATCTGCGGGCAGTCGATATTCTGCGGGCGCGGCAGGCAACTGGTTTATTGAAAAGAAA
TCGTATTAGCGCGGCACAGTGA

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12758.31 Da        Isoelectric Point: 5.0491

>AT37784 WP_096810298.1 NZ_AP023452:859183-859524 [Citrobacter koseri]
MKSTGSENDSFLQWGLNRNVTPCFGARLVQEGNQLHYLADRVSITGEFSNAESLKLDEVFPRFISQMESMLTTSEMNPRY
AHCVTLYHNGFTCEADTLGSCGYVYIAVYPTQR

Download         Length: 342 bp

>AT37784 NZ_AP023452:859183-859524 [Citrobacter koseri]
ATGAAATCTACTGGCTCAGAGAACGATTCATTTCTCCAGTGGGGGCTGAATCGTAATGTGACGCCTTGCTTTGGCGCTCG
TCTGGTACAGGAGGGAAACCAACTGCACTATCTGGCTGACCGGGTCAGCATTACCGGTGAATTCAGTAACGCAGAATCTT
TGAAGTTGGATGAAGTATTCCCACGTTTTATCAGCCAGATGGAATCGATGTTGACCACTAGTGAAATGAATCCTCGCTAT
GCCCACTGCGTCACCCTGTACCACAACGGTTTCACCTGCGAAGCCGATACACTTGGCAGTTGCGGCTATGTATACATCGC
CGTTTACCCCACTCAACGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References