Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 2177..2708 Replicon plasmid pMM59_02
Accession NZ_AP023422
Organism Pusillibacter faecalis strain MM59

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KJS55_RS17205 Protein ID WP_118626743.1
Coordinates 2177..2449 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KJS55_RS17210 Protein ID WP_118626744.1
Coordinates 2436..2708 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJS55_RS17185 1..214 + 214 WP_213543945.1 hypothetical protein -
KJS55_RS17190 (MM59RIKEN_34750) 477..1436 + 960 WP_118626741.1 hypothetical protein -
KJS55_RS17195 (MM59RIKEN_34760) 1488..1637 - 150 WP_177610831.1 hypothetical protein -
KJS55_RS17200 (MM59RIKEN_34770) 1654..2148 - 495 WP_118626742.1 hypothetical protein -
KJS55_RS17205 (MM59RIKEN_34780) 2177..2449 - 273 WP_118626743.1 type II toxin-antitoxin system YafQ family toxin Toxin
KJS55_RS17210 (MM59RIKEN_34790) 2436..2708 - 273 WP_118626744.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
KJS55_RS17215 (MM59RIKEN_34800) 2942..4444 - 1503 WP_177610833.1 hypothetical protein -
KJS55_RS17220 (MM59RIKEN_34810) 4830..6134 - 1305 WP_228300620.1 plasmid recombination protein -
KJS55_RS17225 (MM59RIKEN_34820) 6530..7489 + 960 WP_118626741.1 hypothetical protein -
KJS55_RS17230 (MM59RIKEN_34830) 7541..7690 - 150 WP_177610831.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-86)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10688.38 Da        Isoelectric Point: 6.7016

>T37698 WP_118626743.1 NZ_AP023422:c2449-2177 [Pusillibacter faecalis]
MLTIKYQTAFKKDYKRIVRRGYDVRLLEEVISILAEQKPLPEIYRDHNLSGDYIGCRECHITPDWLLIYEIKNDELVLCL
TRTGTHSDLF

Download         Length: 273 bp

>T37698 NZ_AP023422:c2449-2177 [Pusillibacter faecalis]
ATGCTGACGATTAAGTATCAGACGGCCTTTAAGAAGGACTATAAGAGAATTGTCCGGAGAGGCTATGACGTGCGGCTGCT
GGAGGAAGTAATTAGTATTTTGGCGGAACAAAAGCCGCTGCCGGAGATATATCGGGATCATAACTTGTCCGGAGATTATA
TCGGGTGCAGGGAATGCCATATAACTCCGGACTGGCTTTTGATCTATGAAATCAAGAATGATGAGCTTGTTCTCTGCTTG
ACCAGAACGGGAACGCATAGTGACTTGTTCTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10078.52 Da        Isoelectric Point: 4.3322

>AT37698 WP_118626744.1 NZ_AP023422:c2708-2436 [Pusillibacter faecalis]
MASTNINIRMDTDLKMQFEAFCADMGMTMTTAFNVFAKKAVREYRIPFEISGEVPNAVTRKAIEDVENGIGMSRAFSSVK
ELMEDLNADD

Download         Length: 273 bp

>AT37698 NZ_AP023422:c2708-2436 [Pusillibacter faecalis]
ATGGCAAGCACGAATATCAATATCCGCATGGATACTGACTTGAAGATGCAGTTTGAGGCTTTTTGCGCTGATATGGGAAT
GACGATGACAACCGCTTTCAATGTTTTTGCAAAAAAGGCGGTGCGTGAGTATCGTATTCCCTTTGAGATCAGCGGCGAAG
TGCCGAATGCTGTCACGAGAAAAGCAATCGAGGACGTAGAGAATGGGATTGGAATGAGCAGGGCTTTTTCCTCCGTAAAA
GAGCTGATGGAGGATCTGAATGCTGACGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References