Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 39492..40174 Replicon plasmid pFMUON74
Accession NZ_AP023397
Organism Nocardia wallacei strain FMUON74

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NWFMUON74_RS35430 Protein ID WP_187689643.1
Coordinates 39492..39920 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NWFMUON74_RS35435 Protein ID WP_187689644.1
Coordinates 39917..40174 (-) Length 86 a.a.

Genomic Context

NWFMUON74_RS35395NWFMUON74_RS35400NWFMUON74_RS35405NWFMUON74_RS35445NWFMUON74_RS35470NWFMUON74_RS35410NWFMUON74_RS35415NWFMUON74_RS35420NWFMUON74_RS35425NWFMUON74_RS35430NWFMUON74_RS35435NWFMUON74_RS35440NWFMUON74_RS35450NWFMUON74_RS35455NWFMUON74_RS35460NWFMUON74_RS35465NWFMUON74_RS35475NWFMUON74_RS35480NWFMUON74_RS35485
Location: 35159..35746 (588 bp)
Type: Others
Protein ID: WP_187689636.1
Location: 36001..36594 (594 bp)
Type: Others
Protein ID: WP_187689637.1
Location: 36607..37041 (435 bp)
Type: Others
Protein ID: WP_187689638.1
Location: 40843..41025 (183 bp)
Type: Others
Protein ID: WP_187689646.1
Location: 43400..43684 (285 bp)
Type: Others
Protein ID: WP_187689651.1
Location: 37038..37274 (237 bp)
Type: Others
Protein ID: WP_187689639.1
Location: 37364..38383 (1020 bp)
Type: Others
Protein ID: WP_187689640.1
Location: 38449..38838 (390 bp)
Type: Others
Protein ID: WP_187689641.1
Location: 39025..39432 (408 bp)
Type: Others
Protein ID: WP_187689642.1
Location: 39492..39920 (429 bp)
Type: Toxin
Protein ID: WP_187689643.1
Location: 39917..40174 (258 bp)
Type: Antitoxin
Protein ID: WP_187689644.1
Location: 40363..40707 (345 bp)
Type: Others
Protein ID: WP_187689645.1
Location: 41109..41282 (174 bp)
Type: Others
Protein ID: WP_187689647.1
Location: 41506..42069 (564 bp)
Type: Others
Protein ID: WP_187689648.1
Location: 42171..42596 (426 bp)
Type: Others
Protein ID: WP_187689649.1
Location: 42625..42861 (237 bp)
Type: Others
Protein ID: WP_187689650.1
Location: 43704..44009 (306 bp)
Type: Others
Protein ID: WP_187689652.1
Location: 44111..44536 (426 bp)
Type: Others
Protein ID: WP_187689653.1
Location: 44626..44847 (222 bp)
Type: Others
Protein ID: WP_187689654.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NWFMUON74_RS3539535159..35746+588WP_187689636.1HD domain-containing protein-
NWFMUON74_RS3540036001..36594+594WP_187689637.1GNAT family N-acetyltransferase-
NWFMUON74_RS3540536607..37041+435WP_187689638.1hypothetical protein-
NWFMUON74_RS3541037038..37274-237WP_187689639.1hypothetical protein-
NWFMUON74_RS3541537364..38383-1020WP_187689640.1site-specific integrase-
NWFMUON74_RS3542038449..38838-390WP_187689641.1hypothetical protein-
NWFMUON74_RS3542539025..39432-408WP_187689642.1hypothetical protein-
NWFMUON74_RS3543039492..39920-429WP_187689643.1PIN domain-containing proteinToxin
NWFMUON74_RS3543539917..40174-258WP_187689644.1hypothetical proteinAntitoxin
NWFMUON74_RS3544040363..40707-345WP_187689645.1hypothetical protein-
NWFMUON74_RS3544540843..41025+183WP_187689646.1hypothetical protein-
NWFMUON74_RS3545041109..41282-174WP_187689647.1hypothetical protein-
NWFMUON74_RS3545541506..42069-564WP_187689648.1hypothetical protein-
NWFMUON74_RS3546042171..42596-426WP_187689649.1hypothetical protein-
NWFMUON74_RS3546542625..42861-237WP_187689650.1hypothetical protein-
NWFMUON74_RS3547043400..43684+285WP_187689651.1hypothetical protein-
NWFMUON74_RS3547543704..44009-306WP_187689652.1hypothetical protein-
NWFMUON74_RS3548044111..44536-426WP_187689653.1hypothetical protein-
NWFMUON74_RS3548544626..44847-222WP_187689654.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..6043460434


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15182.09 Da        Isoelectric Point: 4.5271

>T37693 WP_187689643.1 NZ_AP023397:c39920-39492 [Nocardia wallacei]
VIILDTNVISEPFAKNPDLRVAAWFDAQSAETLYLTTVTVGELRYGIAAMPAGRRRDEYAAWLEDRTLPAFSGRILSYDL
AATTEYARLRAAARAAGLAVATADGMIAATAAAAGFTVATRDTSPFEAAGVPTIDPWQSEQR

Download         Length: 429 bp

>T37693 NZ_AP023397:c39920-39492 [Nocardia wallacei]
GTGATCATCCTGGACACCAACGTCATCAGCGAACCGTTCGCCAAGAACCCCGACCTGCGGGTAGCGGCATGGTTCGACGC
ACAGAGCGCCGAAACCCTCTACCTGACCACCGTCACCGTCGGCGAACTCCGCTACGGGATCGCGGCCATGCCCGCCGGCC
GACGCCGCGACGAATACGCCGCATGGCTCGAAGACCGCACCCTGCCCGCGTTCTCCGGCCGCATCCTCTCCTATGACCTG
GCCGCCACCACCGAATACGCGCGCCTGCGCGCCGCCGCCCGCGCCGCAGGGCTCGCCGTCGCCACCGCGGACGGCATGAT
CGCCGCCACGGCGGCCGCCGCAGGCTTCACCGTCGCCACCCGCGACACCTCGCCGTTCGAGGCCGCCGGAGTGCCCACCA
TCGACCCGTGGCAATCGGAGCAACGATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9701.84 Da        Isoelectric Point: 5.2082

>AT37693 WP_187689644.1 NZ_AP023397:c40174-39917 [Nocardia wallacei]
MKNVTIRNLSDEVHRAIRQRAAGNERSIEAEMRAILSDAVQPAERIKLGSLLFAGISEENRLTDDERETYFGRDRTPSEP
LEFGR

Download         Length: 258 bp

>AT37693 NZ_AP023397:c40174-39917 [Nocardia wallacei]
ATGAAGAACGTGACGATCCGAAATCTGTCCGACGAAGTGCACCGCGCCATCCGCCAGCGCGCGGCCGGGAACGAACGCAG
CATCGAAGCCGAGATGCGCGCCATCCTCAGCGACGCCGTACAACCGGCCGAGCGGATCAAACTCGGCAGCCTCCTGTTCG
CGGGCATCAGCGAAGAGAACCGGCTCACCGACGACGAACGCGAAACCTACTTCGGCCGCGACCGCACCCCGTCCGAACCG
CTGGAGTTCGGCCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References