37670

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 4117293..4117837 Replicon chromosome
Accession NZ_AP023362
Organism Mycolicibacterium sp. TY81

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag KI240_RS19805 Protein ID WP_073694732.1
Coordinates 4117293..4117589 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag KI240_RS19810 Protein ID WP_073694733.1
Coordinates 4117586..4117837 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI240_RS19790 (MTY81_40430) 4113440..4114168 + 729 WP_073694729.1 phosphatidylserine decarboxylase -
KI240_RS19795 (MTY81_40440) 4114165..4115055 + 891 WP_073694730.1 CDP-diacylglycerol--serine O-phosphatidyltransferase -
KI240_RS19800 (MTY81_40450) 4115052..4117262 + 2211 WP_212807106.1 AAA family ATPase -
KI240_RS19805 (MTY81_40460) 4117293..4117589 - 297 WP_073694732.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KI240_RS19810 4117586..4117837 - 252 WP_073694733.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
KI240_RS19815 (MTY81_40470) 4117898..4118485 - 588 WP_073694734.1 TetR/AcrR family transcriptional regulator -
KI240_RS19820 (MTY81_40490) 4118577..4119851 + 1275 Protein_3937 NADH:flavin oxidoreductase/NADH oxidase family protein -
KI240_RS19825 (MTY81_40500) 4119848..4120474 + 627 WP_212807107.1 hypothetical protein -
KI240_RS19830 (MTY81_40510) 4120437..4121951 - 1515 WP_212807108.1 zinc ribbon domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(4-73)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11436.94 Da        Isoelectric Point: 6.6350

>T37670 WP_073694732.1 NZ_AP023362:c4117589-4117293 [Mycolicibacterium sp. TY81]
VSRYVLSPAARADLEDVWDYTCERWNADQAQAYVREIQHAIERIAESPMIGRACDDVRPGYRKHAVGSHVLYYRLISGEI
IDVVRILHQRMDVPRHFD

Download         Length: 297 bp

>T37670 NZ_AP023362:c4117589-4117293 [Mycolicibacterium sp. TY81]
GTGAGCCGTTATGTACTTTCGCCCGCGGCGCGCGCCGACTTGGAAGATGTCTGGGACTACACATGTGAGCGCTGGAACGC
TGATCAGGCGCAGGCGTACGTTCGGGAGATTCAACATGCCATCGAACGCATCGCGGAGTCGCCGATGATCGGGCGAGCGT
GCGACGACGTTCGCCCGGGTTACCGGAAACATGCGGTGGGATCGCACGTGCTGTATTACCGGCTCATCTCCGGGGAAATC
ATCGACGTCGTGCGCATCCTCCATCAGCGGATGGATGTGCCTCGGCACTTTGACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9510.36 Da        Isoelectric Point: 5.7425

>AT37670 WP_073694733.1 NZ_AP023362:c4117837-4117586 [Mycolicibacterium sp. TY81]
VGRNTSFSLDEHYSAFIETEVASGRYRSASDVVRSALRLLEDRETRLRALRQALVDGERSGESTEFDFDEFVSRKRAEGS
HRQ

Download         Length: 252 bp

>AT37670 NZ_AP023362:c4117837-4117586 [Mycolicibacterium sp. TY81]
GTGGGCAGGAACACCTCATTCAGTCTCGATGAGCACTACAGCGCGTTCATCGAGACTGAAGTCGCGTCCGGTCGTTATCG
ATCGGCCAGTGACGTAGTGCGATCCGCATTGCGACTGCTCGAGGATCGGGAGACTCGACTGAGGGCGTTGCGCCAGGCCC
TTGTGGATGGTGAACGTAGCGGTGAATCAACAGAATTCGACTTTGATGAGTTCGTATCGCGCAAACGGGCCGAGGGTTCC
CATCGTCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References