Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Fic(toxin)
Location 6152269..6152849 Replicon chromosome
Accession NZ_AP023355
Organism Actinocatenispora thailandica strain NBRC 105041

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag Athai_RS27545 Protein ID WP_203966327.1
Coordinates 6152490..6152849 (+) Length 120 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag Athai_RS27540 Protein ID WP_203964173.1
Coordinates 6152269..6152466 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Athai_RS27515 6148968..6149591 + 624 WP_203964169.1 putative glycolipid-binding domain-containing protein -
Athai_RS27520 6149686..6150777 - 1092 WP_203964170.1 PLP-dependent cysteine synthase family protein -
Athai_RS27525 6150837..6151388 - 552 WP_203964171.1 Clp protease -
Athai_RS27530 6151391..6151612 - 222 WP_203964172.1 helix-turn-helix domain-containing protein -
Athai_RS27535 6151772..6152227 + 456 WP_203966325.1 methylglyoxal synthase -
Athai_RS27540 6152269..6152466 + 198 WP_203964173.1 hypothetical protein Antitoxin
Athai_RS27545 6152490..6152849 + 360 WP_203966327.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
Athai_RS27550 6152839..6153387 - 549 WP_203964174.1 Lrp/AsnC family transcriptional regulator -
Athai_RS27555 6153469..6154668 + 1200 WP_203964175.1 4-hydroxyphenylpyruvate dioxygenase -
Athai_RS27560 6154959..6155303 + 345 WP_203964176.1 DUF2510 domain-containing protein -
Athai_RS27565 6155264..6155812 + 549 WP_203964177.1 RDD family protein -
Athai_RS27570 6155805..6156893 + 1089 WP_203964178.1 histidinol-phosphate transaminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(17-116)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 12426.24 Da        Isoelectric Point: 5.4905

>T37657 WP_203966327.1 NZ_AP023355:6152490-6152849 [Actinocatenispora thailandica]
IEDIVAIASTIAGERIAPRDLGLLASAVARPQASMFGQDAYPDLHVKAAALLHSLAANHAFVDGNKRTALNSAIVFLDIN
GHPLSKPVDIDAMVKLTLAAAQSQLDLAAIADGLRTFTD

Download         Length: 360 bp

>T37657 NZ_AP023355:6152490-6152849 [Actinocatenispora thailandica]
ATCGAGGACATTGTCGCCATCGCGAGCACGATCGCCGGCGAGCGAATCGCGCCACGTGACCTCGGCCTGCTCGCCTCGGC
AGTGGCCCGGCCGCAAGCGAGCATGTTCGGGCAGGATGCCTATCCCGACCTACACGTGAAGGCCGCCGCGCTGCTGCATT
CACTGGCCGCCAACCATGCCTTCGTGGACGGGAACAAGCGCACCGCGCTCAACTCCGCGATCGTGTTCCTCGACATCAAT
GGTCATCCGTTGAGCAAGCCGGTTGACATCGATGCCATGGTGAAGCTGACCCTTGCCGCGGCTCAATCGCAGCTTGATCT
CGCCGCGATCGCCGACGGGCTTCGCACATTCACCGATTGA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7272.30 Da        Isoelectric Point: 6.2180

>AT37657 WP_203964173.1 NZ_AP023355:6152269-6152466 [Actinocatenispora thailandica]
MAALNVAFDDDEMDELRRVAEAEGVSMKALVHKATIHSLHERRVQTATKRTVDALAEVNKRLAEL

Download         Length: 198 bp

>AT37657 NZ_AP023355:6152269-6152466 [Actinocatenispora thailandica]
ATGGCAGCACTCAACGTGGCTTTCGACGATGATGAGATGGACGAGCTGCGCCGAGTCGCCGAAGCAGAGGGCGTCAGCAT
GAAGGCCCTGGTGCACAAGGCGACGATTCATTCTCTGCACGAGCGCAGGGTGCAGACGGCGACGAAACGTACGGTCGACG
CGCTGGCCGAGGTGAACAAGCGGCTGGCCGAGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References