Detailed information of TA system TA037652

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PfiT-PfiA/ParE(toxin)
• Location: 5845378..5845984
• Replicon: chromosome
• Accession: NZ_AP023348
• Organism: Pseudomonas sp. RtIB026

Toxin (Protein)

• Gene name: PfiT
• Uniprot ID: -
• Locus tag: PRtIB026_RS26315
• Protein ID: WP_186712059.1
• Coordinates: 5845637..5845984 (+)
• Length: 116 a.a.

Antitoxin (Protein)

• Gene name: PfiA
• Uniprot ID: -
• Locus tag: PRtIB026_RS26310
• Protein ID: WP_203648638.1
• Coordinates: 5845378..5845626 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PRtIB026_RS26290	5842069..5842767	+	699	WP_203648630.1	HNH endonuclease	-
PRtIB026_RS26295	5842769..5843167	+	399	WP_203648632.1	hypothetical protein	-
PRtIB026_RS26300	5843863..5845008	+	1146	WP_203648634.1	nitrite reductase, copper-containing	-
PRtIB026_RS26305	5845086..5845298	+	213	WP_203648636.1	DUF3079 domain-containing protein	-
PRtIB026_RS26310	5845378..5845626	+	249	WP_203648638.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
PRtIB026_RS26315	5845637..5845984	+	348	WP_186712059.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PRtIB026_RS26320	5846187..5846600	-	414	WP_203648640.1	type II toxin-antitoxin system HicB family antitoxin	-
PRtIB026_RS26325	5846618..5846809	-	192	WP_050703388.1	type II toxin-antitoxin system HicA family toxin	-
PRtIB026_RS26330	5847339..5848364	-	1026	WP_203646634.1	IS110 family transposase	-
PRtIB026_RS26335	5848694..5849239	-	546	WP_203648642.1	HDIG domain-containing protein	-
PRtIB026_RS26340	5849312..5850367	-	1056	WP_203648644.1	haloacid dehalogenase-like hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	5839723..5848364	8641

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-99)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 116 a.a.
• Molecular weight: 12685.52 Da
• Isoelectric Point: 5.5378

>T37652 WP_186712059.1 NZ_AP023348:5845637-5845984 [Pseudomonas sp. RtIB026]
MAKPSIRFTDSASQSLEDQVHHLAVYNGAAAALDTITNLIDAIEHKLSMAPAAYPISPQASELGVAHYRELNLAGYRVFY
EIVEDGRVVAVELVVRQKQSIEQALVRYCLIYPLA

Nucleotide

• Length: 348 bp

>T37652 NZ_AP023348:5845637-5845984 [Pseudomonas sp. RtIB026]
ATGGCCAAGCCAAGTATTCGTTTCACCGACTCCGCGTCACAAAGCCTTGAGGACCAGGTTCATCATCTGGCGGTCTACAA
CGGCGCCGCGGCAGCACTCGACACGATCACCAACCTGATCGATGCCATTGAGCACAAGCTCTCGATGGCCCCCGCCGCCT
ATCCCATCAGTCCTCAGGCCAGCGAGCTGGGCGTGGCGCACTACCGGGAACTGAATCTTGCGGGTTACCGTGTGTTCTAC
GAGATCGTCGAGGACGGGCGAGTGGTGGCCGTGGAGCTGGTCGTGAGGCAGAAGCAAAGCATCGAGCAGGCGCTTGTCCG
TTACTGCCTCATCTATCCCCTGGCCTGA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9297.55 Da
• Isoelectric Point: 7.2013

>AT37652 WP_203648638.1 NZ_AP023348:5845378-5845626 [Pseudomonas sp. RtIB026]
MRVETISYLKRHAADLDLEEPMVVTQNGTPAYVIESYADRKRRDEAIALVKLLAMGSREYAQGKHSSADDLKARLSRKFA
ED

Nucleotide

• Length: 249 bp

>AT37652 NZ_AP023348:5845378-5845626 [Pseudomonas sp. RtIB026]
ATGAGAGTCGAAACTATCAGCTACCTGAAGCGCCATGCCGCAGACCTCGACCTGGAAGAGCCCATGGTGGTCACCCAAAA
TGGCACACCCGCGTATGTGATTGAATCCTATGCAGATCGCAAACGTCGCGACGAAGCCATCGCCCTGGTCAAGCTTCTGG
CCATGGGCTCACGCGAGTACGCTCAAGGCAAACACAGCTCTGCGGACGATCTCAAGGCGCGTCTTTCCAGGAAGTTCGCC
GAGGACTAA