Detailed information of TA system TA037650

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 5231739..5232081
• Replicon: chromosome
• Accession: NZ_AP023348
• Organism: Pseudomonas sp. RtIB026

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PRtIB026_RS23515
• Protein ID: WP_203648017.1
• Coordinates: 5231968..5232081 (+)
• Length: 38 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: PRtIB026_RS23510
• Protein ID: WP_203648016.1
• Coordinates: 5231739..5231978 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PRtIB026_RS23500	5229310..5230791	+	1482	WP_203648015.1	methylenetetrahydrofolate reductase C-terminal domain-containing protein	-
PRtIB026_RS23505	5231229..5231636	+	408	WP_203652708.1	DUF2846 domain-containing protein	-
PRtIB026_RS23510	5231739..5231978	+	240	WP_203648016.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
PRtIB026_RS23515	5231968..5232081	+	114	WP_203648017.1	stability protein StbE	Toxin
PRtIB026_RS23520	5232044..5234401	-	2358	WP_203648018.1	transporter substrate-binding domain-containing protein	-
PRtIB026_RS23525	5234401..5235093	-	693	WP_203652709.1	response regulator transcription factor	-
PRtIB026_RS23530	5235319..5236764	-	1446	WP_203648019.1	YadA-like family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	5221794..5257081	35287

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-64)

Sequences

Toxin

Protein

• Length: 38 a.a.
• Molecular weight: 4419.26 Da
• Isoelectric Point: 11.3085

>T37650 WP_203648017.1 NZ_AP023348:5231968-5232081 [Pseudomonas sp. RtIB026]
MTYNLDFNARALKEWRKLGDTIRQPLKKKRFLLPVSA

Nucleotide

• Length: 114 bp

>T37650 NZ_AP023348:5231968-5232081 [Pseudomonas sp. RtIB026]
ATGACCTATAACCTCGACTTTAATGCGCGCGCGCTCAAGGAATGGCGAAAGCTCGGCGACACCATTCGCCAGCCGCTCAA
GAAGAAGCGCTTTCTTTTGCCAGTATCAGCCTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9034.45 Da
• Isoelectric Point: 4.8146

>AT37650 WP_203648016.1 NZ_AP023348:5231739-5231978 [Pseudomonas sp. RtIB026]
MASINVRIDDDLKVRAYRELEKLGVTPSELMRQALQYVAERGQLPFKPVLLTEEDEALLATVRERLAAPQRVRVTLDDL

Nucleotide

• Length: 240 bp

>AT37650 NZ_AP023348:5231739-5231978 [Pseudomonas sp. RtIB026]
ATGGCGTCCATCAATGTGCGTATCGACGACGACCTCAAAGTGCGCGCCTACCGTGAGCTGGAAAAACTGGGTGTAACCCC
TTCCGAGCTGATGCGCCAGGCACTGCAATACGTCGCTGAGCGTGGGCAACTGCCGTTCAAACCCGTGTTGCTGACCGAAG
AGGATGAAGCATTGCTCGCCACGGTACGCGAACGCCTGGCCGCGCCGCAGAGGGTAAGGGTAACGCTGGATGACCTATAA