Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-DUF971
Location 1807391..1807991 Replicon chromosome
Accession NZ_AP023348
Organism Pseudomonas sp. RtIB026

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PRtIB026_RS08295 Protein ID WP_203651484.1
Coordinates 1807689..1807991 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PRtIB026_RS08290 Protein ID WP_203651483.1
Coordinates 1807391..1807696 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PRtIB026_RS08260 1802697..1803146 + 450 WP_203651477.1 hypothetical protein -
PRtIB026_RS08265 1803416..1803739 + 324 WP_186600151.1 hypothetical protein -
PRtIB026_RS08270 1804174..1804413 + 240 WP_203651478.1 hypothetical protein -
PRtIB026_RS08275 1804916..1805515 + 600 WP_203651479.1 hypothetical protein -
PRtIB026_RS08280 1805596..1806117 + 522 WP_203651481.1 pentapeptide repeat-containing protein -
PRtIB026_RS08285 1806392..1807317 + 926 Protein_1617 DMT family transporter -
PRtIB026_RS08290 1807391..1807696 - 306 WP_203651483.1 putative addiction module antidote protein Antitoxin
PRtIB026_RS08295 1807689..1807991 - 303 WP_203651484.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PRtIB026_RS08300 1808069..1809235 - 1167 WP_203651485.1 MFS transporter -
PRtIB026_RS08305 1809342..1810235 + 894 WP_203651486.1 LysR family transcriptional regulator -
PRtIB026_RS08310 1810699..1812078 - 1380 WP_203651487.1 sodium:solute symporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(18-90)

Antitoxin

Cro/C1-type helix-turn-helix domain

(45-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11311.00 Da        Isoelectric Point: 10.6106

>T37647 WP_203651484.1 NZ_AP023348:c1807991-1807689 [Pseudomonas sp. RtIB026]
MKTIESSSFRRWLIGLRDTTARARIVARINRLKEGLAGDVSPVGHGMSELRVHYGPGYRVYFHQCGDTLIILLCGGDKGS
QQRDIKAARQILQSWRIQND

Download         Length: 303 bp

>T37647 NZ_AP023348:c1807991-1807689 [Pseudomonas sp. RtIB026]
ATGAAAACCATCGAATCCAGCAGTTTCAGGCGTTGGCTGATCGGGCTTAGGGATACCACGGCAAGGGCCAGAATCGTCGC
TCGTATCAACCGGCTCAAGGAAGGGCTAGCGGGTGACGTTTCACCGGTCGGCCATGGTATGAGTGAGCTGAGAGTCCATT
ACGGCCCAGGCTATCGGGTGTACTTTCACCAATGCGGCGATACCTTGATCATCCTGCTTTGCGGCGGCGACAAAGGCAGC
CAGCAGCGGGACATCAAGGCAGCCCGACAGATCCTGCAGTCGTGGAGGATACAAAATGACTGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10939.42 Da        Isoelectric Point: 5.5900

>AT37647 WP_203651483.1 NZ_AP023348:c1807696-1807391 [Pseudomonas sp. RtIB026]
MTETFHEFDAAAYLTSPETIAQFMTDALETGDAAYVAKAVGVVARARGMSELAKETGLSREQLYRSFSEHGNPTLKSFLT
VMKALGIDMAARPHLVQQGVS

Download         Length: 306 bp

>AT37647 NZ_AP023348:c1807696-1807391 [Pseudomonas sp. RtIB026]
ATGACTGAAACGTTCCATGAGTTCGACGCCGCCGCCTATCTGACTTCCCCGGAAACCATCGCGCAGTTCATGACCGATGC
ATTGGAGACAGGGGATGCAGCCTACGTGGCAAAAGCTGTGGGCGTGGTGGCTCGCGCCAGGGGCATGAGTGAACTGGCAA
AGGAAACAGGCCTGTCTCGCGAACAGCTTTACCGCTCATTCAGTGAACACGGCAATCCAACGCTCAAGTCGTTCCTGACT
GTGATGAAAGCGCTGGGAATAGACATGGCTGCCAGACCTCACCTGGTCCAGCAAGGCGTGAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References