Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1898000..1898145 Replicon chromosome
Accession NZ_AP023337
Organism Klebsiella pneumoniae strain MH15-269M

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1898036..1898138 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1898000..1898145 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRS02_RS09170 1893130..1895190 + 2061 WP_004151449.1 oligopeptidase B -
HRS02_RS09175 1895194..1895853 - 660 WP_002911407.1 exodeoxyribonuclease X -
HRS02_RS09180 1895932..1896162 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HRS02_RS09185 1896275..1896649 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HRS02_RS09190 1896653..1897522 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
HRS02_RS09195 1897539..1897877 + 339 WP_004189269.1 YebY family protein -
- 1898000..1898145 - 146 - - Antitoxin
- 1898036..1898138 + 103 - - Toxin
HRS02_RS09200 1898512..1898655 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HRS02_RS09205 1898760..1899728 - 969 WP_004151446.1 VirK/YbjX family protein -
HRS02_RS09210 1899885..1900538 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
HRS02_RS09215 1900535..1900726 - 192 WP_002911395.1 YebW family protein -
HRS02_RS09220 1900824..1901063 - 240 WP_002911393.1 YebV family protein -
HRS02_RS09225 1901179..1902612 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T37621 NZ_AP023337:1898036-1898138 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT37621 NZ_AP023337:c1898145-1898000 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References