Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 655622..656201 Replicon chromosome
Accession NZ_AP023326
Organism Acetobacter aceti strain JCM20276

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag AAJCM20276_RS03145 Protein ID WP_185230000.1
Coordinates 655622..656008 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag AAJCM20276_RS03150 Protein ID WP_099349564.1
Coordinates 655998..656201 (-) Length 68 a.a.

Genomic Context

AAJCM20276_RS03120AAJCM20276_RS03125AAJCM20276_RS03160AAJCM20276_RS03165AAJCM20276_RS03170AAJCM20276_RS03175AAJCM20276_RS03115AAJCM20276_RS03130AAJCM20276_RS03135AAJCM20276_RS03140AAJCM20276_RS03145AAJCM20276_RS03150AAJCM20276_RS03155
Location: 652028..652705 (678 bp)
Type: Others
Protein ID: WP_099349521.1
Location: 652734..653087 (354 bp)
Type: Others
Protein ID: WP_145995996.1
Location: 657119..657442 (324 bp)
Type: Others
Protein ID: WP_180952916.1
Location: 657439..658173 (735 bp)
Type: Others
Protein ID: WP_185230002.1
Location: 658218..659153 (936 bp)
Type: Others
Protein ID: WP_185230003.1
Location: 659486..659947 (462 bp)
Type: Others
Protein ID: WP_185230004.1
Location: 651238..651834 (597 bp)
Type: Others
Protein ID: WP_185229999.1
Location: 653063..653413 (351 bp)
Type: Others
Protein ID: WP_099349523.1
Location: 653779..654042 (264 bp)
Type: Others
Protein ID: WP_099349524.1
Location: 654695..655363 (669 bp)
Type: Others
Protein ID: WP_099349560.1
Location: 655622..656008 (387 bp)
Type: Toxin
Protein ID: WP_185230000.1
Location: 655998..656201 (204 bp)
Type: Antitoxin
Protein ID: WP_099349564.1
Location: 656313..656825 (513 bp)
Type: Others
Protein ID: WP_185230001.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AAJCM20276_RS03115651238..651834-597WP_185229999.1recombinase family protein-
AAJCM20276_RS03120652028..652705+678WP_099349521.1hypothetical protein-
AAJCM20276_RS03125652734..653087+354WP_145995996.1hypothetical protein-
AAJCM20276_RS03130653063..653413-351WP_099349523.1hypothetical protein-
AAJCM20276_RS03135653779..654042-264WP_099349524.1hypothetical protein-
AAJCM20276_RS03140654695..655363-669WP_099349560.1recombinase family protein-
AAJCM20276_RS03145655622..656008-387WP_185230000.1PIN domain-containing proteinToxin
AAJCM20276_RS03150655998..656201-204WP_099349564.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
AAJCM20276_RS03155656313..656825-513WP_185230001.1type II secretion system protein-
AAJCM20276_RS03160657119..657442+324WP_180952916.1MobC family plasmid mobilization relaxosome protein-
AAJCM20276_RS03165657439..658173+735WP_185230002.1hypothetical protein-
AAJCM20276_RS03170658218..659153+936WP_185230003.1hypothetical protein-
AAJCM20276_RS03175659486..659947+462WP_185230004.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--641153..66493923786


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-110)

Antitoxin

SpoVT-AbrB domain

(5-34)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14430.74 Da        Isoelectric Point: 4.8484

>T37606 WP_185230000.1 NZ_AP023326:c656008-655622 [Acetobacter aceti]
MLLDSNVILYGIIQDDRKTPIAARLMEQGGFLSVQTLNEVTNVLRKKKKDWEFINRLLEDLYISFSVLPMDIEVHKAGVK
IAGRYGLSTYDSMIVACAYVNGIETVLSEDMQNGQVIFDTVRIVNPFG

Download         Length: 387 bp

>T37606 NZ_AP023326:c656008-655622 [Acetobacter aceti]
ATGCTTCTTGATTCCAATGTCATTCTGTATGGCATCATTCAGGATGACAGAAAGACGCCAATCGCTGCCAGACTGATGGA
ACAGGGTGGCTTCCTCAGTGTCCAGACACTGAATGAAGTGACCAATGTCCTGCGGAAGAAAAAGAAGGACTGGGAGTTCA
TCAACAGACTTCTGGAAGACCTGTATATCTCCTTTTCCGTTCTACCTATGGATATCGAAGTTCATAAGGCAGGCGTGAAG
ATAGCTGGACGTTATGGTCTGTCTACATATGATTCCATGATTGTGGCCTGTGCTTACGTGAATGGGATTGAGACCGTGCT
GTCCGAGGATATGCAGAATGGACAGGTCATCTTCGATACTGTCAGGATCGTCAATCCATTTGGGTAG

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7684.82 Da        Isoelectric Point: 10.4777

>AT37606 WP_099349564.1 NZ_AP023326:c656201-655998 [Acetobacter aceti]
MQVSKWGNSLAVRIPRHMLKEHGIQEGDNVEITIRRVKSRKEALTDLKELGKQLPADFRIERTSDAS

Download         Length: 204 bp

>AT37606 NZ_AP023326:c656201-655998 [Acetobacter aceti]
ATGCAGGTCTCGAAATGGGGGAACAGTCTGGCCGTTCGTATCCCCCGTCACATGCTGAAGGAGCACGGGATTCAGGAAGG
TGATAACGTGGAGATCACCATCAGACGGGTGAAATCCCGCAAGGAAGCCCTGACTGACCTGAAAGAACTTGGAAAGCAGT
TGCCTGCTGACTTCCGTATCGAACGGACTTCTGATGCTTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References