37604

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 125577..126609 Replicon chromosome
Accession NZ_AP023326
Organism Acetobacter aceti strain JCM20276

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag AAJCM20276_RS00580 Protein ID WP_099348021.1
Coordinates 126046..126609 (+) Length 188 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag AAJCM20276_RS00575 Protein ID WP_180952801.1
Coordinates 125577..126041 (+) Length 155 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AAJCM20276_RS00565 121362..123551 - 2190 WP_099348023.1 prolyl oligopeptidase family protein -
AAJCM20276_RS00570 124132..125442 + 1311 WP_099348022.1 site-specific integrase -
AAJCM20276_RS00575 125577..126041 + 465 WP_180952801.1 helix-turn-helix domain-containing protein Antitoxin
AAJCM20276_RS00580 126046..126609 + 564 WP_099348021.1 PIN domain-containing protein Toxin
AAJCM20276_RS00585 126852..128099 + 1248 WP_099348020.1 glycosyl transferase family 2 -
AAJCM20276_RS00590 128240..128443 - 204 WP_099348019.1 helix-turn-helix domain-containing protein -
AAJCM20276_RS00595 128604..128774 + 171 WP_180952800.1 hypothetical protein -
AAJCM20276_RS00600 128837..129061 + 225 WP_099348018.1 hypothetical protein -
AAJCM20276_RS00605 129058..129480 + 423 WP_099348017.1 hypothetical protein -
AAJCM20276_RS00610 129648..130493 + 846 WP_180952799.1 hypothetical protein -
AAJCM20276_RS00615 130755..131009 + 255 WP_099348015.1 DNA-binding protein -
AAJCM20276_RS00620 131006..131485 + 480 WP_099348014.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-111)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 188 a.a.        Molecular weight: 21323.61 Da        Isoelectric Point: 5.6791

>T37604 WP_099348021.1 NZ_AP023326:126046-126609 [Acetobacter aceti]
MAFVALLDACVLYPAPLRDLLMRLAVTGLFRARWSERIHEEWTRGVLRERPELKDRLPRTCQRMNDAVPDALVSDYESIA
EGLSLPDPDDRHVLAAAIVGRADVVVTFNLKDFPADVLRLYGIEAQHPDIFVRHTLSLDPPMALSAIRAQRQALKNPPQT
VSEFLDTLRRQQLPETVAFLRDWVDFL

Download         Length: 564 bp

>T37604 NZ_AP023326:126046-126609 [Acetobacter aceti]
ATGGCCTTCGTCGCCCTGCTGGATGCCTGTGTCCTATATCCTGCGCCACTCCGTGATCTGCTCATGCGTCTTGCGGTTAC
TGGATTGTTCCGGGCTCGATGGAGTGAGCGCATTCATGAAGAATGGACGCGTGGCGTGCTGCGGGAACGCCCTGAACTGA
AAGACCGTTTGCCTCGCACCTGCCAGCGCATGAATGATGCCGTTCCGGATGCTCTCGTATCTGATTATGAGAGCATTGCG
GAGGGCCTGTCCCTGCCAGATCCTGATGACCGGCATGTCCTTGCTGCTGCCATCGTTGGACGGGCTGATGTGGTTGTCAC
ATTTAATCTGAAAGACTTCCCGGCAGATGTCCTCCGTCTCTATGGAATAGAGGCGCAACATCCTGACATTTTCGTCCGTC
ACACACTTTCCCTTGACCCGCCGATGGCTCTTTCTGCCATTCGGGCGCAACGCCAAGCACTGAAGAACCCACCTCAGACT
GTATCAGAATTCTTGGATACTCTCCGGCGACAACAGCTACCGGAAACAGTCGCTTTTCTGCGGGACTGGGTGGATTTTCT
ATAA

Antitoxin


Download         Length: 155 a.a.        Molecular weight: 16976.44 Da        Isoelectric Point: 4.8744

>AT37604 WP_180952801.1 NZ_AP023326:125577-126041 [Acetobacter aceti]
MAMTALKAIDPGFPSEKDRQAAQEASRALSRLSGRGCVQVEAVADHEEKQTFVLPAEAVRLLTDILSLLAEGRPVVVTPK
DVMVTTQEAADMLNVSRPYVVKLIEDGRLKHQMVGTHRRILMGDLLAYKAEQDEKSRNALDALTDEAQELDMGY

Download         Length: 465 bp

>AT37604 NZ_AP023326:125577-126041 [Acetobacter aceti]
ATGGCTATGACCGCTTTGAAGGCGATTGATCCGGGCTTTCCCTCCGAAAAAGATCGTCAAGCTGCACAGGAGGCAAGCCG
CGCCCTATCCAGATTGAGTGGACGTGGATGTGTGCAAGTTGAGGCTGTAGCCGACCACGAGGAAAAACAGACCTTCGTGT
TACCTGCCGAAGCCGTAAGATTGCTGACGGACATATTGTCCTTGCTGGCTGAAGGCAGGCCCGTTGTTGTTACGCCAAAA
GACGTGATGGTGACGACGCAGGAAGCTGCCGACATGCTGAATGTGTCCAGACCCTATGTCGTCAAACTGATTGAGGATGG
CCGGTTGAAACACCAGATGGTCGGCACACATCGGAGAATTCTGATGGGTGATCTGCTGGCCTATAAGGCGGAACAGGATG
AGAAAAGCCGCAATGCTCTGGATGCTCTGACGGACGAGGCTCAGGAACTGGATATGGGCTACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References