Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1973075..1973346 Replicon chromosome
Accession NZ_AP023286
Organism Escherichia coli strain 2018-18.25PC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1973205..1973308 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1973075..1973346 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMH23_RS09355 1969630..1970292 - 663 WP_000944258.1 exodeoxyribonuclease X -
JMH23_RS09360 1970316..1970972 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
JMH23_RS09365 1971074..1971304 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JMH23_RS09370 1971443..1971817 + 375 WP_000168747.1 CopC domain-containing protein YobA -
JMH23_RS09375 1971821..1972693 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
JMH23_RS09380 1972706..1973047 + 342 WP_000976472.1 YebY family protein -
- 1973075..1973346 - 272 - - Antitoxin
- 1973205..1973308 + 104 - - Toxin
JMH23_RS09385 1973443..1974099 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
JMH23_RS09390 1974100..1974291 - 192 WP_001338167.1 YebW family protein -
JMH23_RS09395 1974396..1974632 - 237 WP_001338166.1 DUF1480 family protein -
JMH23_RS09400 1974750..1976189 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T37149 NZ_AP023286:1973205-1973308 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT37149 NZ_AP023286:c1973346-1973075 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References